Values CatLog read from this paper
A single amino acid limits the substrate specificity of Thermus thermophilus uridine-cytidine kinase to cytidine
PMID 21539325doi:10.1021/bi102054nOpen in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 12 records (32 values) from this paper: uridine-cytidine kinase homologue (ttCK), thymidine phosphorylase / pyrimidine-nucleoside phosphorylase (ttTP) from Thermus thermophilus.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| thymidine phosphorylase / pyrimidine-nucleoside phosphorylase (ttTP) | Thermus thermophilus | thymidine | 0.9 | 0.045 | 22 | pH 7.2 | Open record: thymidine phosphorylase / pyrimidine-nucleoside phosphorylase (ttTP), thymidine |
| thymidine phosphorylase / pyrimidine-nucleoside phosphorylase (ttTP) | Thermus thermophilus | uridine | 2.6 | 0.016 | 100 | pH 7.2 | Open record: thymidine phosphorylase / pyrimidine-nucleoside phosphorylase (ttTP), uridine |
| uridine-cytidine kinase homologue (ttCK) | Thermus thermophilus | cytidine | 4.1 | 0.072 | 57 | pH 7.2, 25 °C | Open record: uridine-cytidine kinase homologue (ttCK), cytidine |
| uridine-cytidine kinase homologue (ttCK)variant Y59F | Thermus thermophilus | cytidine | 6.4 | 0.2 | 32 | pH 7.2, 25 °C | Open record: uridine-cytidine kinase homologue (ttCK) variant Y59F, cytidine |
| uridine-cytidine kinase homologue (ttCK)variant Y93F | Thermus thermophilus | cytidine | 5.9 | 0.1 | 57 | pH 7.2, 25 °C | Open record: uridine-cytidine kinase homologue (ttCK) variant Y93F, cytidine |
| uridine-cytidine kinase homologue (ttCK)variant Y93F | Thermus thermophilus | uridine | — | — | 1.2 × 10⁻⁵ | pH 7.2, 25 °C | Open record: uridine-cytidine kinase homologue (ttCK) variant Y93F, uridine |
| uridine-cytidine kinase homologue (ttCK)variant Y93H | Thermus thermophilus | cytidine | 8.4 | 0.22 | 38 | pH 7.2, 25 °C | Open record: uridine-cytidine kinase homologue (ttCK) variant Y93H, cytidine |
| uridine-cytidine kinase homologue (ttCK)variant Y93H | Thermus thermophilus | uridine | 9.2 | 0.36 | 26 | pH 7.2, 25 °C | Open record: uridine-cytidine kinase homologue (ttCK) variant Y93H, uridine |
| uridine-cytidine kinase homologue (ttCK)variant Y93L | Thermus thermophilus | cytidine | 10 | 0.42 | 24 | pH 7.2, 25 °C | Open record: uridine-cytidine kinase homologue (ttCK) variant Y93L, cytidine |
| uridine-cytidine kinase homologue (ttCK)variant Y93L | Thermus thermophilus | uridine | — | — | 6.6 × 10⁻⁶ | pH 7.2, 25 °C | Open record: uridine-cytidine kinase homologue (ttCK) variant Y93L, uridine |
| uridine-cytidine kinase homologue (ttCK)variant Y93Q | Thermus thermophilus | cytidine | 2.8 | 0.23 | 12 | pH 7.2, 25 °C | Open record: uridine-cytidine kinase homologue (ttCK) variant Y93Q, cytidine |
| uridine-cytidine kinase homologue (ttCK)variant Y93Q | Thermus thermophilus | uridine | 1.1 | 1.6 | 0.72 | pH 7.2, 25 °C | Open record: uridine-cytidine kinase homologue (ttCK) variant Y93Q, uridine |