EC 2.4.2.2: pyrimidine-nucleoside phosphorylase
TransferasesOpen in Browse
CatLog read 11 records for EC 2.4.2.2 from 2 papers, for 2 organisms. Names in these papers: TPHyor (M. hyorhinis thymidine phosphorylase / pyrimidine nucleoside phosphorylase, PyNP), thymidine phosphorylase / pyrimidine-nucleoside phosphorylase (ttTP).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 10 records for EC 2.4.2.2 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.4.2.2 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Characterization of pyrimidine nucleoside phosphorylase of Mycoplasma hyorhinis: implications for the clinical efficacy of nucleoside analogues | Mycoplasma hyorhinis | 9 |
| A single amino acid limits the substrate specificity of Thermus thermophilus uridine-cytidine kinase to cytidine | Thermus thermophilus | 2 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| thymidine phosphorylase / pyrimidine-nucleoside phosphorylase (ttTP) | Thermus thermophilus | thymidine | 0.9 | 0.045 | 22 | pH 7.2 | PMID 21539325 | Open record: thymidine phosphorylase / pyrimidine-nucleoside phosphorylase (ttTP), thymidine |
| thymidine phosphorylase / pyrimidine-nucleoside phosphorylase (ttTP) | Thermus thermophilus | uridine | 2.6 | 0.016 | 100 | pH 7.2 | PMID 21539325 | Open record: thymidine phosphorylase / pyrimidine-nucleoside phosphorylase (ttTP), uridine |
| TPHyor (M. hyorhinis thymidine phosphorylase / pyrimidine nucleoside phosphorylase, PyNP) | Mycoplasma hyorhinis | 2'-deoxyuridine | 24.6 | 0.578 | 43 | pH 7.6, 37 °C | PMID 22475552 | Open record: TPHyor (M. hyorhinis thymidine phosphorylase / pyrimidine nucleoside phosphorylase, PyNP), 2'-deoxyuridine |
| TPHyor (M. hyorhinis thymidine phosphorylase / pyrimidine nucleoside phosphorylase, PyNP) | Mycoplasma hyorhinis | 5-fluoro-2'-deoxyuridine (floxuridine) | 11.9 | 0.169 | 70 | pH 7.6, 37 °C | PMID 22475552 | Open record: TPHyor (M. hyorhinis thymidine phosphorylase / pyrimidine nucleoside phosphorylase, PyNP), 5-fluoro-2'-deoxyuridine (floxuridine) |
| TPHyor (M. hyorhinis thymidine phosphorylase / pyrimidine nucleoside phosphorylase, PyNP) | Mycoplasma hyorhinis | 5-fluorouridine | 6.1 | 0.047 | 130 | pH 7.6, 37 °C | PMID 22475552 | Open record: TPHyor (M. hyorhinis thymidine phosphorylase / pyrimidine nucleoside phosphorylase, PyNP), 5-fluorouridine |
| TPHyor (M. hyorhinis thymidine phosphorylase / pyrimidine nucleoside phosphorylase, PyNP) | Mycoplasma hyorhinis | 5-iodo-2'-deoxyuridine (idoxuridine) | 9.5 | 0.144 | 66 | pH 7.6, 37 °C | PMID 22475552 | Open record: TPHyor (M. hyorhinis thymidine phosphorylase / pyrimidine nucleoside phosphorylase, PyNP), 5-iodo-2'-deoxyuridine (idoxuridine) |
| TPHyor (M. hyorhinis thymidine phosphorylase / pyrimidine nucleoside phosphorylase, PyNP) | Mycoplasma hyorhinis | 5-iodouridine | 6.4 | 0.069 | 93 | pH 7.6, 37 °C | PMID 22475552 | Open record: TPHyor (M. hyorhinis thymidine phosphorylase / pyrimidine nucleoside phosphorylase, PyNP), 5-iodouridine |
| TPHyor (M. hyorhinis thymidine phosphorylase / pyrimidine nucleoside phosphorylase, PyNP) | Mycoplasma hyorhinis | inorganic phosphatecosubstrate dThd (fixed at 10x Km) | 17.5 | 0.797 | 22 | pH 7.6, 37 °C | PMID 22475552 | Open record: TPHyor (M. hyorhinis thymidine phosphorylase / pyrimidine nucleoside phosphorylase, PyNP), inorganic phosphate |
| TPHyor (M. hyorhinis thymidine phosphorylase / pyrimidine nucleoside phosphorylase, PyNP) | Mycoplasma hyorhinis | inorganic phosphatecosubstrate Urd (fixed at 10x Km) | 8.6 | 0.388 | 22 | pH 7.6, 37 °C | PMID 22475552 | Open record: TPHyor (M. hyorhinis thymidine phosphorylase / pyrimidine nucleoside phosphorylase, PyNP), inorganic phosphate |
| TPHyor (M. hyorhinis thymidine phosphorylase / pyrimidine nucleoside phosphorylase, PyNP) | Mycoplasma hyorhinis | thymidine | 21.6 | 0.473 | 46 | pH 7.6, 37 °C | PMID 22475552 | Open record: TPHyor (M. hyorhinis thymidine phosphorylase / pyrimidine nucleoside phosphorylase, PyNP), thymidine |
| TPHyor (M. hyorhinis thymidine phosphorylase / pyrimidine nucleoside phosphorylase, PyNP) | Mycoplasma hyorhinis | uridine | 8.5 | 0.092 | 92 | pH 7.6, 37 °C | PMID 22475552 | Open record: TPHyor (M. hyorhinis thymidine phosphorylase / pyrimidine nucleoside phosphorylase, PyNP), uridine |