Values CatLog read from this paper
Mutagenesis of a conserved glutamate reveals the contribution of electrostatic energy to adenosylcobalamin co-C bond homolysis in ornithine 4,5-aminomutase and methylmalonyl-CoA mutase
PMID 23311430doi:10.1021/bi3012719Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 7 records (13 values) from this paper: methylmalonyl-CoA mutase (MCM), ornithine 4,5-aminomutase (OAM) from Homo sapiens, Clostridium sticklandii.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| methylmalonyl-CoA mutase (MCM) | Homo sapiens | (R,S)-methylmalonyl-CoA | 3.95 | — | — | pH 7.5, 30 °C | Open record: methylmalonyl-CoA mutase (MCM), (R,S)-methylmalonyl-CoA |
| methylmalonyl-CoA mutase (MCM)variant E392A | Homo sapiens | (R,S)-methylmalonyl-CoA | 0.32 | — | — | pH 7.5, 30 °C | Open record: methylmalonyl-CoA mutase (MCM) variant E392A, (R,S)-methylmalonyl-CoA |
| methylmalonyl-CoA mutase (MCM)variant E392D | Homo sapiens | (R,S)-methylmalonyl-CoA | 0.012 | — | — | pH 7.5, 30 °C | Open record: methylmalonyl-CoA mutase (MCM) variant E392D, (R,S)-methylmalonyl-CoA |
| methylmalonyl-CoA mutase (MCM)variant E392Q | Homo sapiens | (R,S)-methylmalonyl-CoA | 0.25 | — | — | pH 7.5, 30 °C | Open record: methylmalonyl-CoA mutase (MCM) variant E392Q, (R,S)-methylmalonyl-CoA |
| ornithine 4,5-aminomutase (OAM)variant E338A | Clostridium sticklandii | D-ornithine | 0.0043 | 0.0606 | 0.07 | Open record: ornithine 4,5-aminomutase (OAM) variant E338A, D-ornithine | |
| ornithine 4,5-aminomutase (OAM)variant E338D | Clostridium sticklandii | D-ornithine | 0.0076 | 0.0302 | 0.25 | Open record: ornithine 4,5-aminomutase (OAM) variant E338D, D-ornithine | |
| ornithine 4,5-aminomutase (OAM)variant E338Q | Clostridium sticklandii | D-ornithine | 0.032 | 0.0427 | 0.75 | Open record: ornithine 4,5-aminomutase (OAM) variant E338Q, D-ornithine |