CatLogenzyme kinetics catalog

Values CatLog read from this paper

Human hereditary glutathione synthetase deficiency: kinetic properties of mutant enzymes

PMID 15056072doi:10.1042/bj20040114Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 16 records (16 values) from this paper: glutathione synthetase from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 6.3.2.3

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
glutathione synthetaseHomo sapiensATP—0.07—pH 8.2, 37 °COpen
glutathione synthetaseHomo sapiensglycine—1.75—pH 8.2, 37 °COpen
glutathione synthetasevariant D219AHomo sapiensATP—1.05—pH 8.2, 37 °COpen
glutathione synthetasevariant D219AHomo sapiensglycine—2.07—pH 8.2, 37 °COpen
glutathione synthetasevariant D219GHomo sapiensATP—0.04—pH 8.2, 37 °COpen
glutathione synthetasevariant D219GHomo sapiensglycine—1.51—pH 8.2, 37 °COpen
glutathione synthetasevariant L188PHomo sapiensATP—0.73—pH 8.2, 37 °COpen
glutathione synthetasevariant L188PHomo sapiensglycine—2.25—pH 8.2, 37 °COpen
glutathione synthetasevariant P314LHomo sapiensATP—0.05—pH 8.2, 37 °COpen
glutathione synthetasevariant P314LHomo sapiensglycine—1.64—pH 8.2, 37 °COpen
glutathione synthetasevariant R283CHomo sapiensATP—0.09—pH 8.2, 37 °COpen
glutathione synthetasevariant R283CHomo sapiensglycine—1.02—pH 8.2, 37 °COpen
glutathione synthetasevariant Y270CHomo sapiensATP—0.05—pH 8.2, 37 °COpen
glutathione synthetasevariant Y270CHomo sapiensglycine—1.43—pH 8.2, 37 °COpen
glutathione synthetasevariant Y270HHomo sapiensATP—0.02—pH 8.2, 37 °COpen
glutathione synthetasevariant Y270HHomo sapiensglycine—1.24—pH 8.2, 37 °COpen