Values CatLog read from this paper
Human histone demethylase LSD1 reads the histone code
PMID 16223729doi:10.1074/jbc.m509549200Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 6 records (18 values) from this paper: histone demethylase LSD1 (lysine-specific demethylase 1) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| histone demethylase LSD1 (lysine-specific demethylase 1) | Homo sapiens | histone H3 N-terminal 21-amino-acid peptide (H3 residues 1-21) dimethylated on Lys450 mM Hepes/NaOH; no added salt (ionic strength 22 mM) | 0.135 | 0.0042 | 32 | pH 7.5, 25 °C | Open record: histone demethylase LSD1 (lysine-specific demethylase 1), histone H3 N-terminal 21-amino-acid peptide (H3 residues 1-21) dimethylated on Lys4 |
| histone demethylase LSD1 (lysine-specific demethylase 1) | Homo sapiens | histone H3 N-terminal 21-amino-acid peptide (H3 residues 1-21) dimethylated on Lys450 mM Hepes/NaOH plus 80 mM NaCl | 0.118 | 0.0128 | 9.2 | pH 7.5, 25 °C | Open record: histone demethylase LSD1 (lysine-specific demethylase 1), histone H3 N-terminal 21-amino-acid peptide (H3 residues 1-21) dimethylated on Lys4 |
| histone demethylase LSD1 (lysine-specific demethylase 1) | Homo sapiens | histone H3 N-terminal 21-amino-acid peptide (H3 residues 1-21) monomethylated on Lys4 | 0.053 | 0.003 | 18 | pH 7.5, 25 °C | Open record: histone demethylase LSD1 (lysine-specific demethylase 1), histone H3 N-terminal 21-amino-acid peptide (H3 residues 1-21) monomethylated on Lys4 |
| histone demethylase LSD1 (lysine-specific demethylase 1) | Homo sapiens | histone H3 N-terminal 21-amino-acid peptide (H3 residues 1-21) monomethylated on Lys4 and acetylated on Lys9 | 0.068 | 0.0175 | 3.8 | pH 7.5, 25 °C | Open record: histone demethylase LSD1 (lysine-specific demethylase 1), histone H3 N-terminal 21-amino-acid peptide (H3 residues 1-21) monomethylated on Lys4 and acetylated on Lys9 |
| histone demethylase LSD1 (lysine-specific demethylase 1) | Homo sapiens | histone H3 N-terminal 21-amino-acid peptide (H3 residues 1-21) monomethylated on Lys4 and monomethylated on Lys9 | 0.093 | 0.0039 | 23 | pH 7.5, 25 °C | Open record: histone demethylase LSD1 (lysine-specific demethylase 1), histone H3 N-terminal 21-amino-acid peptide (H3 residues 1-21) monomethylated on Lys4 and monomethylated on Lys9 |
| histone demethylase LSD1 (lysine-specific demethylase 1) | Homo sapiens | histone H3 N-terminal 30-amino-acid peptide (H3 residues 1-30) monomethylated on Lys4 | 0.048 | 0.0034 | 13 | pH 7.5, 25 °C | Open record: histone demethylase LSD1 (lysine-specific demethylase 1), histone H3 N-terminal 30-amino-acid peptide (H3 residues 1-30) monomethylated on Lys4 |