Values CatLog read from this paper
Synthesis of N3-substituted carboranyl thymidine bioconjugates and their evaluation as substrates of recombinant human thymidine kinase 1
PMID 23318906doi:10.1016/j.ejmech.2012.11.041Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 10 records (20 values) from this paper: thymidine kinase 1 (hTK1) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 10 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| thymidine kinase 1 (hTK1) | Homo sapiens | 3-[1(2)-closo-1,7-carboranylbutyltetrazol-5-yl]thymidine | 0.32 | 0.0174 | 18 calc. | pH 7.6, 37 °C | Open record: thymidine kinase 1 (hTK1), 3-[1(2)-closo-1,7-carboranylbutyltetrazol-5-yl]thymidine |
| thymidine kinase 1 (hTK1) | Homo sapiens | 3-[1(2)-closo-1,7-carboranylbutyltetrazol-5-ylmethyl]thymidine | 0.47 | 0.0563 | 8.3 calc. | pH 7.6, 37 °C | Open record: thymidine kinase 1 (hTK1), 3-[1(2)-closo-1,7-carboranylbutyltetrazol-5-ylmethyl]thymidine |
| thymidine kinase 1 (hTK1) | Homo sapiens | 3-[1(2)-closo-1,7-carboranylethyltetrazol-5-yl]thymidine | 0.35 | 0.0356 | 9.8 calc. | pH 7.6, 37 °C | Open record: thymidine kinase 1 (hTK1), 3-[1(2)-closo-1,7-carboranylethyltetrazol-5-yl]thymidine |
| thymidine kinase 1 (hTK1) | Homo sapiens | 3-[1(2)-closo-1,7-carboranylethyltetrazol-5-ylmethyl]thymidine | 0.44 | 0.0318 | 14 calc. | pH 7.6, 37 °C | Open record: thymidine kinase 1 (hTK1), 3-[1(2)-closo-1,7-carboranylethyltetrazol-5-ylmethyl]thymidine |
| thymidine kinase 1 (hTK1) | Homo sapiens | 3-[1(2)-closo-1,7-carboranylpropyltetrazol-5-yl]thymidine | 0.37 | 0.0799 | 4.6 calc. | pH 7.6, 37 °C | Open record: thymidine kinase 1 (hTK1), 3-[1(2)-closo-1,7-carboranylpropyltetrazol-5-yl]thymidine |
| thymidine kinase 1 (hTK1) | Homo sapiens | 3-[1(2)-closo-1,7-carboranylpropyltetrazol-5-ylmethyl]thymidine | 0.39 | 0.0552 | 7.1 calc. | pH 7.6, 37 °C | Open record: thymidine kinase 1 (hTK1), 3-[1(2)-closo-1,7-carboranylpropyltetrazol-5-ylmethyl]thymidine |
| thymidine kinase 1 (hTK1) | Homo sapiens | 3-[1(2)-propyltetrazol-5-yl]thymidine | 0.34 | 0.014 | 24 calc. | pH 7.6, 37 °C | Open record: thymidine kinase 1 (hTK1), 3-[1(2)-propyltetrazol-5-yl]thymidine |
| thymidine kinase 1 (hTK1) | Homo sapiens | 3-[1(2)-propyltetrazol-5-ylmethyl]thymidine | 0.45 | 0.0373 | 12 calc. | pH 7.6, 37 °C | Open record: thymidine kinase 1 (hTK1), 3-[1(2)-propyltetrazol-5-ylmethyl]thymidine |
| thymidine kinase 1 (hTK1) | Homo sapiens | N5-2OH | 0.42 | 0.0415 | 10 calc. | pH 7.6, 37 °C | Open record: thymidine kinase 1 (hTK1), N5-2OH |
| thymidine kinase 1 (hTK1) | Homo sapiens | thymidine | 0.46 | 0.0049 | 94 calc. | pH 7.6, 37 °C | Open record: thymidine kinase 1 (hTK1), thymidine |