Values CatLog read from this paper
Research Resource: Correlating Human Cytochrome P450 21A2 Crystal Structure and Phenotypes of Mutations in Congenital Adrenal Hyperplasia
PMID 26172259doi:10.1210/me.2015-1127Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 4 records (12 values) from this paper: cytochrome P450 21A2 (steroid 21-hydroxylase) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| cytochrome P450 21A2 (steroid 21-hydroxylase)variant G65E | Homo sapiens | 17α-hydroxyprogesterone | 0.032 | 0.013 | 2.3 | Open record: cytochrome P450 21A2 (steroid 21-hydroxylase) variant G65E, 17α-hydroxyprogesterone | |
| cytochrome P450 21A2 (steroid 21-hydroxylase)variant G65E | Homo sapiens | progesterone | 0.062 | 0.0055 | 11.2 | Open record: cytochrome P450 21A2 (steroid 21-hydroxylase) variant G65E, progesterone | |
| cytochrome P450 21A2 (steroid 21-hydroxylase)variant T296N | Homo sapiens | 17α-hydroxyprogesterone | 0.045 | 4.6 × 10⁻⁴ | 100 | Open record: cytochrome P450 21A2 (steroid 21-hydroxylase) variant T296N, 17α-hydroxyprogesterone | |
| cytochrome P450 21A2 (steroid 21-hydroxylase)variant T296N | Homo sapiens | progesterone | 0.0077 | 0.0011 | 7 | Open record: cytochrome P450 21A2 (steroid 21-hydroxylase) variant T296N, progesterone |