Values CatLog read from this paper
Critical role of the cysteine 323 residue in the catalytic activity of human glutamate dehydrogenase isozymes
PMID 15750346doi:10.1016/s1016-8478(23)13142-6Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 20 records (50 values) from this paper: glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH), glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH)variant C323G | Homo sapiens | 2-oxoglutarate | 17 | 1.4 | 12.1 | 25 °C | Open record: glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH) variant C323G, 2-oxoglutarate |
| glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH)variant C323G | Homo sapiens | NADH | — | 0.119 | 140 | 25 °C | Open record: glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH) variant C323G, NADH |
| glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH)variant C323L | Homo sapiens | 2-oxoglutarate | 17 | 1.34 | 12.7 | 25 °C | Open record: glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH) variant C323L, 2-oxoglutarate |
| glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH)variant C323L | Homo sapiens | NADH | — | 0.117 | 150 | 25 °C | Open record: glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH) variant C323L, NADH |
| glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH)variant C323M | Homo sapiens | 2-oxoglutarate | 19 | 1.38 | 13.8 | 25 °C | Open record: glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH) variant C323M, 2-oxoglutarate |
| glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH)variant C323M | Homo sapiens | NADH | — | 0.119 | 160 | 25 °C | Open record: glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH) variant C323M, NADH |
| glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH)variant C323R | Homo sapiens | 2-oxoglutarate | 15 | 1.39 | 10.8 | 25 °C | Open record: glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH) variant C323R, 2-oxoglutarate |
| glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH)variant C323R | Homo sapiens | NADH | — | 0.122 | 120 | 25 °C | Open record: glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH) variant C323R, NADH |
| glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH)variant C323Y | Homo sapiens | 2-oxoglutarate | 14 | 1.36 | 10.3 | 25 °C | Open record: glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH) variant C323Y, 2-oxoglutarate |
| glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH)variant C323Y | Homo sapiens | NADH | — | 0.129 | 110 | 25 °C | Open record: glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH) variant C323Y, NADH |
| glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH)variant C323G | Homo sapiens | 2-oxoglutarate | 21 | 1.52 | 13.8 | 25 °C | Open record: glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH) variant C323G, 2-oxoglutarate |
| glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH)variant C323G | Homo sapiens | NADH | — | 0.128 | 160 | 25 °C | Open record: glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH) variant C323G, NADH |
| glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH)variant C323L | Homo sapiens | 2-oxoglutarate | 20 | 1.45 | 13.8 | 25 °C | Open record: glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH) variant C323L, 2-oxoglutarate |
| glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH)variant C323L | Homo sapiens | NADH | — | 0.121 | 170 | 25 °C | Open record: glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH) variant C323L, NADH |
| glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH)variant C323M | Homo sapiens | 2-oxoglutarate | 19 | 1.45 | 13.1 | 25 °C | Open record: glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH) variant C323M, 2-oxoglutarate |
| glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH)variant C323M | Homo sapiens | NADH | — | 0.119 | 160 | 25 °C | Open record: glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH) variant C323M, NADH |
| glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH)variant C323R | Homo sapiens | 2-oxoglutarate | 19 | 1.5 | 12.7 | 25 °C | Open record: glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH) variant C323R, 2-oxoglutarate |
| glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH)variant C323R | Homo sapiens | NADH | — | 0.125 | 150 | 25 °C | Open record: glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH) variant C323R, NADH |
| glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH)variant C323Y | Homo sapiens | 2-oxoglutarate | 17 | 1.41 | 12.1 | 25 °C | Open record: glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH) variant C323Y, 2-oxoglutarate |
| glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH)variant C323Y | Homo sapiens | NADH | — | 0.138 | 120 | 25 °C | Open record: glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH) variant C323Y, NADH |