EC 1.4.1.3: glutamate dehydrogenase [NAD(P)+]

OxidoreductasesOpen in Browse

CatLog read 184 records for EC 1.4.1.3 from 12 papers, for 6 organisms. Names in these papers: glutamate dehydrogenase, glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh), human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH), human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH) and 9 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 140 records for EC 1.4.1.3 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.4.1.3 in Browse.

Papers

Papers with records for EC 1.4.1.3
PaperOrganismsRecords
Identification of ADP-ribosylation site in human glutamate dehydrogenase isozymesHomo sapiens36
Identification of the GTP binding site of human glutamate dehydrogenase by cassette mutagenesis and photoaffinity labelingHomo sapiens22
Reactive amino acid residues involved in glutamate-binding of human glutamate dehydrogenase isozymesHomo sapiens22
Critical role of the cysteine 323 residue in the catalytic activity of human glutamate dehydrogenase isozymesHomo sapiens20
Glutamate Dehydrogenase from Thermus thermophilus Is Activated by AMP and Leucine as a Complex with Catalytically Inactive Adenine Phosphoribosyltransferase HomologThermus thermophilus20
Histidine 454 plays an important role in polymerization of human glutamate dehydrogenaseHomo sapiens16
Sequence analysis of glutamate dehydrogenase (GDH) from the hyperthermophilic archaeon Pyrococcus sp. KOD1 and comparison of the enzymatic characteristics of native and recombinant GDHsPyrococcus sp.16
Importance of glutamate 279 for the coenzyme binding of human glutamate dehydrogenaseHomo sapiens12
Heat effect on the structure and activity of the recombinant glutamate dehydrogenase from a hyperthermophilic archaeon Pyrococcus horikoshiiPyrococcus horikoshii6
Important role of Ser443 in different thermal stability of human glutamate dehydrogenase isozymesHomo sapiens6
Control of the NADPH supply and GSH recycling for oxidative stress management in hepatoma and liver mitochondriaRattus norvegicus6
CryoEM and crystal structure analyses reveal the indirect role played by Trp89 in glutamate dehydrogenase enzymatic reactionsThermococcus profundus2

Records

Records for EC 1.4.1.3 read from the paper
EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaperOpen record
glutamate dehydrogenaseHomo sapiens2-oxoglutarate—1.21—pH 8, 25 °CPMID 11600502Open record: glutamate dehydrogenase, 2-oxoglutarate
glutamate dehydrogenaseHomo sapiens2-oxoglutarate1041.258325 °CPMID 12681501Open record: glutamate dehydrogenase, 2-oxoglutarate
glutamate dehydrogenaseHomo sapiensL-glutamate—3.4418.9pH 9.5, 25 °CPMID 12193607Open record: glutamate dehydrogenase, L-glutamate
glutamate dehydrogenaseHomo sapiensNAD+650.7191.55pH 9.5, 25 °CPMID 12193607Open record: glutamate dehydrogenase, NAD+
glutamate dehydrogenaseHomo sapiensNADH—0.081—pH 8, 25 °CPMID 11600502Open record: glutamate dehydrogenase, NADH
glutamate dehydrogenaseHomo sapiensNADH—0.081128425 °CPMID 12681501Open record: glutamate dehydrogenase, NADH
glutamate dehydrogenasevariant E279GHomo sapiensL-glutamate—3.9814.82pH 9.5, 25 °CPMID 12193607Open record: glutamate dehydrogenase variant E279G, L-glutamate
glutamate dehydrogenasevariant E279GHomo sapiensNAD+596.948.5pH 9.5, 25 °CPMID 12193607Open record: glutamate dehydrogenase variant E279G, NAD+
glutamate dehydrogenasevariant E279LHomo sapiensL-glutamate—4.0514.07pH 9.5, 25 °CPMID 12193607Open record: glutamate dehydrogenase variant E279L, L-glutamate
glutamate dehydrogenasevariant E279LHomo sapiensNAD+5710.015.69pH 9.5, 25 °CPMID 12193607Open record: glutamate dehydrogenase variant E279L, NAD+
glutamate dehydrogenasevariant E279MHomo sapiensL-glutamate—3.7613.56pH 9.5, 25 °CPMID 12193607Open record: glutamate dehydrogenase variant E279M, L-glutamate
glutamate dehydrogenasevariant E279MHomo sapiensNAD+519.985.22pH 9.5, 25 °CPMID 12193607Open record: glutamate dehydrogenase variant E279M, NAD+
glutamate dehydrogenasevariant E279RHomo sapiensL-glutamate—4.1214.81pH 9.5, 25 °CPMID 12193607Open record: glutamate dehydrogenase variant E279R, L-glutamate
glutamate dehydrogenasevariant E279RHomo sapiensNAD+617.68.03pH 9.5, 25 °CPMID 12193607Open record: glutamate dehydrogenase variant E279R, NAD+
glutamate dehydrogenasevariant E279YHomo sapiensL-glutamate—3.9417.25pH 9.5, 25 °CPMID 12193607Open record: glutamate dehydrogenase variant E279Y, L-glutamate
glutamate dehydrogenasevariant E279YHomo sapiensNAD+688.358.14pH 9.5, 25 °CPMID 12193607Open record: glutamate dehydrogenase variant E279Y, NAD+
glutamate dehydrogenasevariant G446DHomo sapiens2-oxoglutarate1021.56825 °CPMID 12681501Open record: glutamate dehydrogenase variant G446D, 2-oxoglutarate
glutamate dehydrogenasevariant G446DHomo sapiensNADH—0.089114625 °CPMID 12681501Open record: glutamate dehydrogenase variant G446D, NADH
glutamate dehydrogenasevariant H454YHomo sapiens2-oxoglutarate953.133025 °CPMID 12681501Open record: glutamate dehydrogenase variant H454Y, 2-oxoglutarate
glutamate dehydrogenasevariant H454YHomo sapiensNADH—0.12277825 °CPMID 12681501Open record: glutamate dehydrogenase variant H454Y, NADH
glutamate dehydrogenasevariant K333LHomo sapiens2-oxoglutarate931.297225 °CPMID 12681501Open record: glutamate dehydrogenase variant K333L, 2-oxoglutarate
glutamate dehydrogenasevariant K333LHomo sapiensNADH—0.079117725 °CPMID 12681501Open record: glutamate dehydrogenase variant K333L, NADH
glutamate dehydrogenasevariant K337LHomo sapiens2-oxoglutarate981.456825 °CPMID 12681501Open record: glutamate dehydrogenase variant K337L, 2-oxoglutarate
glutamate dehydrogenasevariant K337LHomo sapiensNADH—0.088111325 °CPMID 12681501Open record: glutamate dehydrogenase variant K337L, NADH
glutamate dehydrogenasevariant K344LHomo sapiens2-oxoglutarate1051.318025 °CPMID 12681501Open record: glutamate dehydrogenase variant K344L, 2-oxoglutarate
glutamate dehydrogenasevariant K344LHomo sapiensNADH—0.09116625 °CPMID 12681501Open record: glutamate dehydrogenase variant K344L, NADH
glutamate dehydrogenasevariant K346LHomo sapiens2-oxoglutarate1001.317625 °CPMID 12681501Open record: glutamate dehydrogenase variant K346L, 2-oxoglutarate
glutamate dehydrogenasevariant K346LHomo sapiensNADH—0.076131525 °CPMID 12681501Open record: glutamate dehydrogenase variant K346L, NADH
glutamate dehydrogenasevariant K450EHomo sapiens2-oxoglutarate—1.31—pH 8, 25 °CPMID 11600502Open record: glutamate dehydrogenase variant K450E, 2-oxoglutarate
glutamate dehydrogenasevariant K450EHomo sapiensNADH—0.086—pH 8, 25 °CPMID 11600502Open record: glutamate dehydrogenase variant K450E, NADH
glutamate dehydrogenasevariant K450GHomo sapiens2-oxoglutarate—1.3—pH 8, 25 °CPMID 11600502Open record: glutamate dehydrogenase variant K450G, 2-oxoglutarate
glutamate dehydrogenasevariant K450GHomo sapiensNADH—0.084—pH 8, 25 °CPMID 11600502Open record: glutamate dehydrogenase variant K450G, NADH
glutamate dehydrogenasevariant K450MHomo sapiens2-oxoglutarate—1.4—pH 8, 25 °CPMID 11600502Open record: glutamate dehydrogenase variant K450M, 2-oxoglutarate
glutamate dehydrogenasevariant K450MHomo sapiensNADH—0.08—pH 8, 25 °CPMID 11600502Open record: glutamate dehydrogenase variant K450M, NADH
glutamate dehydrogenasevariant K450SHomo sapiens2-oxoglutarate—1.28—pH 8, 25 °CPMID 11600502Open record: glutamate dehydrogenase variant K450S, 2-oxoglutarate
glutamate dehydrogenasevariant K450SHomo sapiensNADH—0.084—pH 8, 25 °CPMID 11600502Open record: glutamate dehydrogenase variant K450S, NADH
glutamate dehydrogenasevariant K450YHomo sapiens2-oxoglutarate—1.35—pH 8, 25 °CPMID 11600502Open record: glutamate dehydrogenase variant K450Y, 2-oxoglutarate
glutamate dehydrogenasevariant K450YHomo sapiensNADH—0.088—pH 8, 25 °CPMID 11600502Open record: glutamate dehydrogenase variant K450Y, NADH
glutamate dehydrogenasevariant S445LHomo sapiens2-oxoglutarate1111.477625 °CPMID 12681501Open record: glutamate dehydrogenase variant S445L, 2-oxoglutarate
glutamate dehydrogenasevariant S445LHomo sapiensNADH—0.098113225 °CPMID 12681501Open record: glutamate dehydrogenase variant S445L, NADH
glutamate dehydrogenasevariant Y266EHomo sapiens2-oxoglutarate—1.49—pH 8, 25 °CPMID 11600502Open record: glutamate dehydrogenase variant Y266E, 2-oxoglutarate
glutamate dehydrogenasevariant Y266EHomo sapiensNADH—0.261—pH 8, 25 °CPMID 11600502Open record: glutamate dehydrogenase variant Y266E, NADH
glutamate dehydrogenasevariant Y266GHomo sapiens2-oxoglutarate—1.54—pH 8, 25 °CPMID 11600502Open record: glutamate dehydrogenase variant Y266G, 2-oxoglutarate
glutamate dehydrogenasevariant Y266GHomo sapiensNADH—0.27—pH 8, 25 °CPMID 11600502Open record: glutamate dehydrogenase variant Y266G, NADH
glutamate dehydrogenasevariant Y266MHomo sapiens2-oxoglutarate—1.52—pH 8, 25 °CPMID 11600502Open record: glutamate dehydrogenase variant Y266M, 2-oxoglutarate
glutamate dehydrogenasevariant Y266MHomo sapiensNADH—0.265—pH 8, 25 °CPMID 11600502Open record: glutamate dehydrogenase variant Y266M, NADH
glutamate dehydrogenasevariant Y266RHomo sapiens2-oxoglutarate—1.61—pH 8, 25 °CPMID 11600502Open record: glutamate dehydrogenase variant Y266R, 2-oxoglutarate
glutamate dehydrogenasevariant Y266RHomo sapiensNADH—0.278—pH 8, 25 °CPMID 11600502Open record: glutamate dehydrogenase variant Y266R, NADH
glutamate dehydrogenasevariant Y266SHomo sapiens2-oxoglutarate—1.6—pH 8, 25 °CPMID 11600502Open record: glutamate dehydrogenase variant Y266S, 2-oxoglutarate
glutamate dehydrogenasevariant Y266SHomo sapiensNADH—0.276—pH 8, 25 °CPMID 11600502Open record: glutamate dehydrogenase variant Y266S, NADH
glutamate dehydrogenasevariant W89FThermococcus profundusglutamate0.07333.9680.0185 calc.pH 7.5, 20 °CPMID 39891504Open record: glutamate dehydrogenase variant W89F, glutamate
glutamate dehydrogenasevariant W89FThermococcus profundusnicotinamide adenine dinucleotide phosphate, oxidized form (NADP+)—0.142—pH 7.5, 20 °CPMID 39891504Open record: glutamate dehydrogenase variant W89F, nicotinamide adenine dinucleotide phosphate, oxidized form (NADP+)
glutamate dehydrogenase (GDH)Rattus norvegicus2-oxoglutaratemitochondria isolated from AS-30D rat hepatoma cells—0.271—pH 7.2, 37 °CPMID 30053395Open record: glutamate dehydrogenase (GDH), 2-oxoglutarate
glutamate dehydrogenase (GDH)Rattus norvegicus2-oxoglutaraterat liver mitochondria—0.174—pH 7.2, 37 °CPMID 30053395Open record: glutamate dehydrogenase (GDH), 2-oxoglutarate
glutamate dehydrogenase (GDH)Rattus norvegicusL-glutamate—5.2—pH 7.2, 37 °CPMID 30053395Open record: glutamate dehydrogenase (GDH), L-glutamate
glutamate dehydrogenase (GDH)Rattus norvegicusNADP+—0.491—pH 7.2, 37 °CPMID 30053395Open record: glutamate dehydrogenase (GDH), NADP+
glutamate dehydrogenase (GDH)Rattus norvegicusNADPHmitochondria isolated from AS-30D rat hepatoma cells—0.032—pH 7.2, 37 °CPMID 30053395Open record: glutamate dehydrogenase (GDH), NADPH
glutamate dehydrogenase (GDH)Rattus norvegicusNADPHrat liver mitochondria—0.029—pH 7.2, 37 °CPMID 30053395Open record: glutamate dehydrogenase (GDH), NADPH
glutamate dehydrogenase (KOD1-GDH)Pyrococcus sp.2-oxoglutarate1950.25783pH 7.6PMID 9520268Open record: glutamate dehydrogenase (KOD1-GDH), 2-oxoglutarate
glutamate dehydrogenase (KOD1-GDH)Pyrococcus sp.ammonia—1.3—pH 7.6PMID 9520268Open record: glutamate dehydrogenase (KOD1-GDH), ammonia
glutamate dehydrogenase (KOD1-GDH)Pyrococcus sp.ammonia63——pH 7.6PMID 9520268Open record: glutamate dehydrogenase (KOD1-GDH), ammonia
glutamate dehydrogenase (KOD1-GDH)Pyrococcus sp.ammonia——48pH 7.6PMID 9520268Open record: glutamate dehydrogenase (KOD1-GDH), ammonia
glutamate dehydrogenase (KOD1-GDH)Pyrococcus sp.ammonia—13—pH 7.6PMID 9520268Open record: glutamate dehydrogenase (KOD1-GDH), ammonia
glutamate dehydrogenase (KOD1-GDH)Pyrococcus sp.ammonia168——pH 7.6PMID 9520268Open record: glutamate dehydrogenase (KOD1-GDH), ammonia
glutamate dehydrogenase (KOD1-GDH)Pyrococcus sp.ammonia——13pH 7.6PMID 9520268Open record: glutamate dehydrogenase (KOD1-GDH), ammonia
glutamate dehydrogenase (KOD1-GDH)Pyrococcus sp.L-glutamate—0.32—pH 7.6PMID 9520268Open record: glutamate dehydrogenase (KOD1-GDH), L-glutamate
glutamate dehydrogenase (KOD1-GDH)Pyrococcus sp.L-glutamate40——pH 7.6PMID 9520268Open record: glutamate dehydrogenase (KOD1-GDH), L-glutamate
glutamate dehydrogenase (KOD1-GDH)Pyrococcus sp.L-glutamate——125pH 7.6PMID 9520268Open record: glutamate dehydrogenase (KOD1-GDH), L-glutamate
glutamate dehydrogenase (KOD1-GDH)Pyrococcus sp.L-glutamate—5.5—pH 7.6PMID 9520268Open record: glutamate dehydrogenase (KOD1-GDH), L-glutamate
glutamate dehydrogenase (KOD1-GDH)Pyrococcus sp.L-glutamate162——pH 7.6PMID 9520268Open record: glutamate dehydrogenase (KOD1-GDH), L-glutamate
glutamate dehydrogenase (KOD1-GDH)Pyrococcus sp.L-glutamate——30pH 7.6PMID 9520268Open record: glutamate dehydrogenase (KOD1-GDH), L-glutamate
glutamate dehydrogenase (KOD1-GDH)Pyrococcus sp.NADH900.091005pH 7.6PMID 9520268Open record: glutamate dehydrogenase (KOD1-GDH), NADH
glutamate dehydrogenase (KOD1-GDH)Pyrococcus sp.NADP+1020.081262pH 7.6PMID 9520268Open record: glutamate dehydrogenase (KOD1-GDH), NADP+
glutamate dehydrogenase (KOD1-GDH)Pyrococcus sp.NADPH1120.042787pH 7.6PMID 9520268Open record: glutamate dehydrogenase (KOD1-GDH), NADPH
glutamate dehydrogenase (Pho-GDH)Pyrococcus horikoshii2-oxoglutarate165.30.53310 calc.pH 7.6, 90 °CPMID 12590923Open record: glutamate dehydrogenase (Pho-GDH), 2-oxoglutarate
glutamate dehydrogenase (Pho-GDH)Pyrococcus horikoshiiammonia43.82.8215.5 calc.pH 7.6, 90 °CPMID 12590923Open record: glutamate dehydrogenase (Pho-GDH), ammonia
glutamate dehydrogenase (Pho-GDH)Pyrococcus horikoshiiL-glutamate121.20.6200 calc.pH 7.6, 90 °CPMID 12590923Open record: glutamate dehydrogenase (Pho-GDH), L-glutamate
glutamate dehydrogenase (Pho-GDH)Pyrococcus horikoshiiNADH374.50.0834.5 × 10³ calc.pH 7.6, 90 °CPMID 12590923Open record: glutamate dehydrogenase (Pho-GDH), NADH
glutamate dehydrogenase (Pho-GDH)Pyrococcus horikoshiiNADP+399.60.0251.6 × 10⁴ calc.pH 7.6, 90 °CPMID 12590923Open record: glutamate dehydrogenase (Pho-GDH), NADP+
glutamate dehydrogenase (Pho-GDH)Pyrococcus horikoshiiNADPH387.50.0371.0 × 10⁴ calc.pH 7.6, 90 °CPMID 12590923Open record: glutamate dehydrogenase (Pho-GDH), NADPH
glutamate dehydrogenase isozyme hGDH1variant D172YHomo sapiensL-glutamate573.7115.4pH 9.5, 25 °CPMID 15194228Open record: glutamate dehydrogenase isozyme hGDH1 variant D172Y, L-glutamate
glutamate dehydrogenase isozyme hGDH1variant D172YHomo sapiensNAD+—0.7675pH 9.5, 25 °CPMID 15194228Open record: glutamate dehydrogenase isozyme hGDH1 variant D172Y, NAD+
glutamate dehydrogenase isozyme hGDH1variant G96YHomo sapiensL-glutamate4230.551.4pH 9.5, 25 °CPMID 15194228Open record: glutamate dehydrogenase isozyme hGDH1 variant G96Y, L-glutamate
glutamate dehydrogenase isozyme hGDH1variant G96YHomo sapiensNAD+—0.6564.6pH 9.5, 25 °CPMID 15194228Open record: glutamate dehydrogenase isozyme hGDH1 variant G96Y, NAD+
glutamate dehydrogenase isozyme hGDH1variant K118YHomo sapiensL-glutamate4825.821.9pH 9.5, 25 °CPMID 15194228Open record: glutamate dehydrogenase isozyme hGDH1 variant K118Y, L-glutamate
glutamate dehydrogenase isozyme hGDH1variant K118YHomo sapiensNAD+—0.9451.1pH 9.5, 25 °CPMID 15194228Open record: glutamate dehydrogenase isozyme hGDH1 variant K118Y, NAD+
glutamate dehydrogenase isozyme hGDH1variant K130YHomo sapiensL-glutamate25.510.4pH 9.5, 25 °CPMID 15194228Open record: glutamate dehydrogenase isozyme hGDH1 variant K130Y, L-glutamate
glutamate dehydrogenase isozyme hGDH1variant K130YHomo sapiensNAD+—0.922.2pH 9.5, 25 °CPMID 15194228Open record: glutamate dehydrogenase isozyme hGDH1 variant K130Y, NAD+
glutamate dehydrogenase isozyme hGDH1variant K94YHomo sapiensL-glutamate1121.820.5pH 9.5, 25 °CPMID 15194228Open record: glutamate dehydrogenase isozyme hGDH1 variant K94Y, L-glutamate
glutamate dehydrogenase isozyme hGDH1variant K94YHomo sapiensNAD+—0.7913.9pH 9.5, 25 °CPMID 15194228Open record: glutamate dehydrogenase isozyme hGDH1 variant K94Y, NAD+
glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH)variant C323GHomo sapiens2-oxoglutarate171.412.125 °CPMID 15750346Open record: glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH) variant C323G, 2-oxoglutarate
glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH)variant C323GHomo sapiensNADH—0.11914025 °CPMID 15750346Open record: glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH) variant C323G, NADH
glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH)variant C323LHomo sapiens2-oxoglutarate171.3412.725 °CPMID 15750346Open record: glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH) variant C323L, 2-oxoglutarate
glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH)variant C323LHomo sapiensNADH—0.11715025 °CPMID 15750346Open record: glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH) variant C323L, NADH
glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH)variant C323MHomo sapiens2-oxoglutarate191.3813.825 °CPMID 15750346Open record: glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH) variant C323M, 2-oxoglutarate
glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH)variant C323MHomo sapiensNADH—0.11916025 °CPMID 15750346Open record: glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH) variant C323M, NADH
glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH)variant C323RHomo sapiens2-oxoglutarate151.3910.825 °CPMID 15750346Open record: glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH) variant C323R, 2-oxoglutarate
glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH)variant C323RHomo sapiensNADH—0.12212025 °CPMID 15750346Open record: glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH) variant C323R, NADH
glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH)variant C323YHomo sapiens2-oxoglutarate141.3610.325 °CPMID 15750346Open record: glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH) variant C323Y, 2-oxoglutarate
glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH)variant C323YHomo sapiensNADH—0.12911025 °CPMID 15750346Open record: glutamate dehydrogenase isozyme hGDH1 (house-keeping GDH) variant C323Y, NADH
glutamate dehydrogenase isozyme hGDH2Homo sapiensL-glutamate831.8145.9pH 9.5, 25 °CPMID 15194228Open record: glutamate dehydrogenase isozyme hGDH2, L-glutamate
glutamate dehydrogenase isozyme hGDH2Homo sapiensNAD+—0.59140.7pH 9.5, 25 °CPMID 15194228Open record: glutamate dehydrogenase isozyme hGDH2, NAD+
glutamate dehydrogenase isozyme hGDH2variant D172YHomo sapiensL-glutamate721.7740.7pH 9.5, 25 °CPMID 15194228Open record: glutamate dehydrogenase isozyme hGDH2 variant D172Y, L-glutamate
glutamate dehydrogenase isozyme hGDH2variant D172YHomo sapiensNAD+—0.63114.3pH 9.5, 25 °CPMID 15194228Open record: glutamate dehydrogenase isozyme hGDH2 variant D172Y, NAD+
glutamate dehydrogenase isozyme hGDH2variant G96YHomo sapiensL-glutamate5717.753.2pH 9.5, 25 °CPMID 15194228Open record: glutamate dehydrogenase isozyme hGDH2 variant G96Y, L-glutamate
glutamate dehydrogenase isozyme hGDH2variant G96YHomo sapiensNAD+—0.5898.3pH 9.5, 25 °CPMID 15194228Open record: glutamate dehydrogenase isozyme hGDH2 variant G96Y, NAD+
glutamate dehydrogenase isozyme hGDH2variant K118YHomo sapiensL-glutamate5910.415.7pH 9.5, 25 °CPMID 15194228Open record: glutamate dehydrogenase isozyme hGDH2 variant K118Y, L-glutamate
glutamate dehydrogenase isozyme hGDH2variant K118YHomo sapiensNAD+—0.8271.9pH 9.5, 25 °CPMID 15194228Open record: glutamate dehydrogenase isozyme hGDH2 variant K118Y, NAD+
glutamate dehydrogenase isozyme hGDH2variant K130YHomo sapiensL-glutamate42.981.3pH 9.5, 25 °CPMID 15194228Open record: glutamate dehydrogenase isozyme hGDH2 variant K130Y, L-glutamate
glutamate dehydrogenase isozyme hGDH2variant K130YHomo sapiensNAD+—0.755.3pH 9.5, 25 °CPMID 15194228Open record: glutamate dehydrogenase isozyme hGDH2 variant K130Y, NAD+
glutamate dehydrogenase isozyme hGDH2variant K94YHomo sapiensL-glutamate147.991.8pH 9.5, 25 °CPMID 15194228Open record: glutamate dehydrogenase isozyme hGDH2 variant K94Y, L-glutamate
glutamate dehydrogenase isozyme hGDH2variant K94YHomo sapiensNAD+—0.5525.5pH 9.5, 25 °CPMID 15194228Open record: glutamate dehydrogenase isozyme hGDH2 variant K94Y, NAD+
glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH)variant C323GHomo sapiens2-oxoglutarate211.5213.825 °CPMID 15750346Open record: glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH) variant C323G, 2-oxoglutarate
glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH)variant C323GHomo sapiensNADH—0.12816025 °CPMID 15750346Open record: glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH) variant C323G, NADH
glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH)variant C323LHomo sapiens2-oxoglutarate201.4513.825 °CPMID 15750346Open record: glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH) variant C323L, 2-oxoglutarate
glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH)variant C323LHomo sapiensNADH—0.12117025 °CPMID 15750346Open record: glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH) variant C323L, NADH
glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH)variant C323MHomo sapiens2-oxoglutarate191.4513.125 °CPMID 15750346Open record: glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH) variant C323M, 2-oxoglutarate
glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH)variant C323MHomo sapiensNADH—0.11916025 °CPMID 15750346Open record: glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH) variant C323M, NADH
glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH)variant C323RHomo sapiens2-oxoglutarate191.512.725 °CPMID 15750346Open record: glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH) variant C323R, 2-oxoglutarate
glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH)variant C323RHomo sapiensNADH—0.12515025 °CPMID 15750346Open record: glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH) variant C323R, NADH
glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH)variant C323YHomo sapiens2-oxoglutarate171.4112.125 °CPMID 15750346Open record: glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH) variant C323Y, 2-oxoglutarate
glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH)variant C323YHomo sapiensNADH—0.13812025 °CPMID 15750346Open record: glutamate dehydrogenase isozyme hGDH2 (nerve-specific GDH) variant C323Y, NADH
glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh)Thermus thermophilus2-oxoglutarateeffector: no effector0.230.005145 calc.pH 7, 60 °CPMID 31036724Open record: glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh), 2-oxoglutarate
glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh)Thermus thermophilus2-oxoglutarateeffector: 1 mM AMP0.660.022929 calc.pH 7, 60 °CPMID 31036724Open record: glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh), 2-oxoglutarate
glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh)Thermus thermophilus2-oxoglutarateeffector: 1 mM leucine150.027560 calc.pH 7, 60 °CPMID 31036724Open record: glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh), 2-oxoglutarate
glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh)Thermus thermophilus2-oxoglutarateeffector: 1 mM AMP and 1 mM leucine370.052710 calc.pH 7, 60 °CPMID 31036724Open record: glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh), 2-oxoglutarate
glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh)Thermus thermophilusammoniumeffector: no effector0.31290.011 calc.pH 7, 60 °CPMID 31036724Open record: glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh), ammonium
glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh)Thermus thermophilusammoniumeffector: 1 mM AMP1.1430.026 calc.pH 7, 60 °CPMID 31036724Open record: glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh), ammonium
glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh)Thermus thermophilusammoniumeffector: 1 mM leucine16460.35 calc.pH 7, 60 °CPMID 31036724Open record: glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh), ammonium
glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh)Thermus thermophilusammoniumeffector: 1 mM AMP and 1 mM leucine44331.3 calc.pH 7, 60 °CPMID 31036724Open record: glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh), ammonium
glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh)Thermus thermophilusL-glutamateeffector: 1 mM leucine4.50.4510 calc.pH 7, 60 °CPMID 31036724Open record: glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh), L-glutamate
glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh)Thermus thermophilusL-glutamateeffector: 1 mM AMP and 1 mM leucine130.7717 calc.pH 7, 60 °CPMID 31036724Open record: glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh), L-glutamate
glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh)Thermus thermophilusL-glutamateeffector: no effector1.5——pH 7, 60 °CPMID 31036724Open record: glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh), L-glutamate
glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh)Thermus thermophilusL-glutamateeffector: 1 mM AMP4.4——pH 7, 60 °CPMID 31036724Open record: glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh), L-glutamate
glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh)Thermus thermophilusNAD+effector: no effector2.80.024120 calc.pH 7, 60 °CPMID 31036724Open record: glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh), NAD+
glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh)Thermus thermophilusNAD+effector: 1 mM AMP9.10.1370 calc.pH 7, 60 °CPMID 31036724Open record: glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh), NAD+
glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh)Thermus thermophilusNAD+effector: 1 mM leucine3.70.05666 calc.pH 7, 60 °CPMID 31036724Open record: glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh), NAD+
glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh)Thermus thermophilusNAD+effector: 1 mM AMP and 1 mM leucine120.1675 calc.pH 7, 60 °CPMID 31036724Open record: glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh), NAD+
glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh)Thermus thermophilusNADHeffector: no effector0.20.00825 calc.pH 7, 60 °CPMID 31036724Open record: glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh), NADH
glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh)Thermus thermophilusNADHeffector: 1 mM AMP0.720.0058120 calc.pH 7, 60 °CPMID 31036724Open record: glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh), NADH
glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh)Thermus thermophilusNADHeffector: 1 mM leucine9.10.0033.0 × 10³ calc.pH 7, 60 °CPMID 31036724Open record: glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh), NADH
glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh)Thermus thermophilusNADHeffector: 1 mM AMP and 1 mM leucine290.00535.5 × 10³ calc.pH 7, 60 °CPMID 31036724Open record: glutamate dehydrogenase TtGDH-APRTh complex (GdhA-GdhB-APRTh), NADH
hGDH1Homo sapiens2-oxoglutarate1041.2581.3pH 8, 25 °CPMID 15044002Open record: hGDH1, 2-oxoglutarate
hGDH1Homo sapiensNADH—0.0811.28 × 10³pH 8, 25 °CPMID 15044002Open record: hGDH1, NADH
hGDH2Homo sapiens2-oxoglutarate1301.3993.5pH 8, 25 °CPMID 15044002Open record: hGDH2, 2-oxoglutarate
hGDH2Homo sapiensNADH—0.0861.51 × 10³pH 8, 25 °CPMID 15044002Open record: hGDH2, NADH
hGDH2variant S443RHomo sapiens2-oxoglutarate1341.4195pH 8, 25 °CPMID 15044002Open record: hGDH2 variant S443R, 2-oxoglutarate
hGDH2variant S443RHomo sapiensNADH—0.0881.52 × 10³pH 8, 25 °CPMID 15044002Open record: hGDH2 variant S443R, NADH
human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH)variant C119AHomo sapiens2-oxoglutarate811.942.625 °CPMID 16023112Open record: human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH) variant C119A, 2-oxoglutarate
human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH)variant C119AHomo sapiensNADH—0.0990025 °CPMID 16023112Open record: human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH) variant C119A, NADH
human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH)variant C119GHomo sapiens2-oxoglutarate771.9439.725 °CPMID 16023112Open record: human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH) variant C119G, 2-oxoglutarate
human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH)variant C119GHomo sapiensNADH—0.09284025 °CPMID 16023112Open record: human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH) variant C119G, NADH
human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH)variant C119YHomo sapiens2-oxoglutarate791.8642.525 °CPMID 16023112Open record: human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH) variant C119Y, 2-oxoglutarate
human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH)variant C119YHomo sapiensNADH—0.09187025 °CPMID 16023112Open record: human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH) variant C119Y, NADH
human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH)variant C274AHomo sapiens2-oxoglutarate901.464.325 °CPMID 16023112Open record: human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH) variant C274A, 2-oxoglutarate
human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH)variant C274AHomo sapiensNADH—0.18948025 °CPMID 16023112Open record: human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH) variant C274A, NADH
human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH)variant C274GHomo sapiens2-oxoglutarate911.1678.425 °CPMID 16023112Open record: human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH) variant C274G, 2-oxoglutarate
human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH)variant C274GHomo sapiensNADH—0.18150025 °CPMID 16023112Open record: human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH) variant C274G, NADH
human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH)variant C274YHomo sapiens2-oxoglutarate881.3764.225 °CPMID 16023112Open record: human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH) variant C274Y, 2-oxoglutarate
human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH)variant C274YHomo sapiensNADH—0.17849025 °CPMID 16023112Open record: human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH) variant C274Y, NADH
human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH)variant C59AHomo sapiens2-oxoglutarate901.464.325 °CPMID 16023112Open record: human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH) variant C59A, 2-oxoglutarate
human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH)variant C59AHomo sapiensNADH—0.09793025 °CPMID 16023112Open record: human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH) variant C59A, NADH
human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH)variant C59GHomo sapiens2-oxoglutarate911.3467.925 °CPMID 16023112Open record: human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH) variant C59G, 2-oxoglutarate
human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH)variant C59GHomo sapiensNADH—0.09497025 °CPMID 16023112Open record: human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH) variant C59G, NADH
human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH)variant C59YHomo sapiens2-oxoglutarate851.3662.525 °CPMID 16023112Open record: human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH) variant C59Y, 2-oxoglutarate
human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH)variant C59YHomo sapiensNADH—0.09986025 °CPMID 16023112Open record: human glutamate dehydrogenase 1 (hGDH1, house-keeping GDH) variant C59Y, NADH
human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH)variant C119AHomo sapiens2-oxoglutarate1052.1249.525 °CPMID 16023112Open record: human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH) variant C119A, 2-oxoglutarate
human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH)variant C119AHomo sapiensNADH—0.1011.04 × 10³25 °CPMID 16023112Open record: human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH) variant C119A, NADH
human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH)variant C119GHomo sapiens2-oxoglutarate1012.1846.325 °CPMID 16023112Open record: human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH) variant C119G, 2-oxoglutarate
human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH)variant C119GHomo sapiensNADH—0.0981.03 × 10³25 °CPMID 16023112Open record: human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH) variant C119G, NADH
human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH)variant C119YHomo sapiens2-oxoglutarate1032.2645.625 °CPMID 16023112Open record: human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH) variant C119Y, 2-oxoglutarate
human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH)variant C119YHomo sapiensNADH—0.10895025 °CPMID 16023112Open record: human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH) variant C119Y, NADH
human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH)variant C274AHomo sapiens2-oxoglutarate1141.5971.725 °CPMID 16023112Open record: human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH) variant C274A, 2-oxoglutarate
human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH)variant C274AHomo sapiensNADH—0.16967025 °CPMID 16023112Open record: human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH) variant C274A, NADH
human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH)variant C274GHomo sapiens2-oxoglutarate1091.586925 °CPMID 16023112Open record: human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH) variant C274G, 2-oxoglutarate
human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH)variant C274GHomo sapiensNADH—0.17562025 °CPMID 16023112Open record: human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH) variant C274G, NADH
human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH)variant C274YHomo sapiens2-oxoglutarate1001.6660.225 °CPMID 16023112Open record: human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH) variant C274Y, 2-oxoglutarate
human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH)variant C274YHomo sapiensNADH—0.17657025 °CPMID 16023112Open record: human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH) variant C274Y, NADH
human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH)variant C59AHomo sapiens2-oxoglutarate1171.6172.725 °CPMID 16023112Open record: human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH) variant C59A, 2-oxoglutarate
human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH)variant C59AHomo sapiensNADH—0.0991.18 × 10³25 °CPMID 16023112Open record: human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH) variant C59A, NADH
human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH)variant C59GHomo sapiens2-oxoglutarate1101.6765.925 °CPMID 16023112Open record: human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH) variant C59G, 2-oxoglutarate
human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH)variant C59GHomo sapiensNADH—0.1061.04 × 10³25 °CPMID 16023112Open record: human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH) variant C59G, NADH
human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH)variant C59YHomo sapiens2-oxoglutarate1081.5868.425 °CPMID 16023112Open record: human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH) variant C59Y, 2-oxoglutarate
human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH)variant C59YHomo sapiensNADH—0.1021.06 × 10³25 °CPMID 16023112Open record: human glutamate dehydrogenase 2 (hGDH2, nerve-specific GDH) variant C59Y, NADH