Values CatLog read from this paper
Characterisation of the bifunctional dihydrofolate synthase-folylpolyglutamate synthase from Plasmodium falciparum; a potential novel target for antimalarial antifolate inhibition
PMID 20350571doi:10.1016/j.molbiopara.2010.03.012Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 5 records (5 values) from this paper: dihydrofolate synthase–folylpolyglutamate synthase (DHFS activity), dihydrofolate synthase–folylpolyglutamate synthase (FPGS activity) from Plasmodium falciparum.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| dihydrofolate synthase–folylpolyglutamate synthase (DHFS activity) | Plasmodium falciparum | 7,8-dihydropteroatenon-linear Michaelis-Menten fit | — | 8.8 × 10⁻⁴ | — | pH 10, 37 °C | Open record: dihydrofolate synthase–folylpolyglutamate synthase (DHFS activity), 7,8-dihydropteroate |
| dihydrofolate synthase–folylpolyglutamate synthase (DHFS activity) | Plasmodium falciparum | 7,8-dihydropteroate | 0.04 | — | — | pH 10, 37 °C | Open record: dihydrofolate synthase–folylpolyglutamate synthase (DHFS activity), 7,8-dihydropteroate |
| dihydrofolate synthase–folylpolyglutamate synthase (DHFS activity) | Plasmodium falciparum | ATP | — | 0.0228 | — | pH 10, 37 °C | Open record: dihydrofolate synthase–folylpolyglutamate synthase (DHFS activity), ATP |
| dihydrofolate synthase–folylpolyglutamate synthase (DHFS activity) | Plasmodium falciparum | L-glutamate | — | 0.00597 | — | pH 10, 37 °C | Open record: dihydrofolate synthase–folylpolyglutamate synthase (DHFS activity), L-glutamate |
| dihydrofolate synthase–folylpolyglutamate synthase (FPGS activity) | Plasmodium falciparum | 5,6,7,8-tetrahydrofolate | — | 9.6 × 10⁻⁴ | — | pH 10, 37 °C | Open record: dihydrofolate synthase–folylpolyglutamate synthase (FPGS activity), 5,6,7,8-tetrahydrofolate |