EC 6.3.2.17: tetrahydrofolate synthase

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CatLog read 94 records for EC 6.3.2.17 from 5 papers, for 3 organisms. Names in these papers: cytosolic folylpolyglutamate synthetase (FPGS), folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS), folylpolyglutamate synthase (FPGS), cytosolic isozyme, folylpolyglutamate synthetase (FPGS) and 1 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 135 records for EC 6.3.2.17 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 6.3.2.17 in Browse.

Papers

Papers with records for EC 6.3.2.17
Paper	Organisms	Records
Purification and properties of human cytosolic folylpoly-gamma-glutamate synthetase and organization, localization, and differential splicing of its gene	Homo sapiens	27
Identification of three key active site residues in the C-terminal domain of human recombinant folylpoly-gamma-glutamate synthetase by site-directed mutagenesis	Homo sapiens	24
Human cytosolic folylpoly-gamma-glutamate synthase	Homo sapiens	24
Structural and functional similarities in the ADP-forming amide bond ligase superfamily: implications for a substrate-induced conformational change in folylpolyglutamate synthetase	Lactobacillus casei	18
Characterisation of the bifunctional dihydrofolate synthase-folylpolyglutamate synthase from Plasmodium falciparum; a potential novel target for antimalarial antifolate inhibition	Plasmodium falciparum	1

Records

Records for EC 6.3.2.17 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
cytosolic folylpolyglutamate synthetase (FPGS)	Homo sapiens	(6R)-10-formyltetrahydropteroyldi-γ-glutamate	—	0.0027	—	37 °C	PMID 8662720	Open record: cytosolic folylpolyglutamate synthetase (FPGS), (6R)-10-formyltetrahydropteroyldi-γ-glutamate
cytosolic folylpolyglutamate synthetase (FPGS)	Homo sapiens	(6R)-10-formyltetrahydropteroylglutamic acid ((6R)-10-formyltetrahydrofolate)	—	0.0037	—	37 °C	PMID 8662720	Open record: cytosolic folylpolyglutamate synthetase (FPGS), (6R)-10-formyltetrahydropteroylglutamic acid ((6R)-10-formyltetrahydrofolate)
cytosolic folylpolyglutamate synthetase (FPGS)	Homo sapiens	(6RS)-tetrahydropteroylglutamic acid ((6RS)-tetrahydrofolate)	—	0.0016	—	37 °C	PMID 8662720	Open record: cytosolic folylpolyglutamate synthetase (FPGS), (6RS)-tetrahydropteroylglutamic acid ((6RS)-tetrahydrofolate)
cytosolic folylpolyglutamate synthetase (FPGS)	Homo sapiens	(6S)-5-formyltetrahydrofolate (folinate)	—	0.105	—	37 °C	PMID 8662720	Open record: cytosolic folylpolyglutamate synthetase (FPGS), (6S)-5-formyltetrahydrofolate (folinate)
cytosolic folylpolyglutamate synthetase (FPGS)	Homo sapiens	(6S)-5-formyltetrahydropteroyldi-γ-glutamate	—	0.013	—	37 °C	PMID 8662720	Open record: cytosolic folylpolyglutamate synthetase (FPGS), (6S)-5-formyltetrahydropteroyldi-γ-glutamate
cytosolic folylpolyglutamate synthetase (FPGS)	Homo sapiens	(6S)-5-methyltetrahydropteroylglutamic acid ((6S)-5-methyltetrahydrofolate)	—	0.048	—	37 °C	PMID 8662720	Open record: cytosolic folylpolyglutamate synthetase (FPGS), (6S)-5-methyltetrahydropteroylglutamic acid ((6S)-5-methyltetrahydrofolate)
cytosolic folylpolyglutamate synthetase (FPGS)	Homo sapiens	(6S)-tetrahydropteroyldi-γ-glutamate	—	0.0033	—	37 °C	PMID 8662720	Open record: cytosolic folylpolyglutamate synthetase (FPGS), (6S)-tetrahydropteroyldi-γ-glutamate
cytosolic folylpolyglutamate synthetase (FPGS)	Homo sapiens	(6S)-tetrahydropteroylglutamic acid ((6S)-tetrahydrofolate)	0.99	0.0044	225	37 °C	PMID 8662720	Open record: cytosolic folylpolyglutamate synthetase (FPGS), (6S)-tetrahydropteroylglutamic acid ((6S)-tetrahydrofolate)
cytosolic folylpolyglutamate synthetase (FPGS)	Homo sapiens	(6S)-tetrahydropteroylpenta-γ-glutamate	—	0.0014	—	37 °C	PMID 8662720	Open record: cytosolic folylpolyglutamate synthetase (FPGS), (6S)-tetrahydropteroylpenta-γ-glutamate
cytosolic folylpolyglutamate synthetase (FPGS)	Homo sapiens	(6S)-tetrahydropteroyltetra-γ-glutamate	—	0.0016	—	37 °C	PMID 8662720	Open record: cytosolic folylpolyglutamate synthetase (FPGS), (6S)-tetrahydropteroyltetra-γ-glutamate
cytosolic folylpolyglutamate synthetase (FPGS)	Homo sapiens	(6S)-tetrahydropteroyltri-γ-glutamate	—	0.0014	—	37 °C	PMID 8662720	Open record: cytosolic folylpolyglutamate synthetase (FPGS), (6S)-tetrahydropteroyltri-γ-glutamate
cytosolic folylpolyglutamate synthetase (FPGS)	Homo sapiens	2-methyl-5,8-dideazaisofolate	—	0.0028	—	37 °C	PMID 8662720	Open record: cytosolic folylpolyglutamate synthetase (FPGS), 2-methyl-5,8-dideazaisofolate
cytosolic folylpolyglutamate synthetase (FPGS)	Homo sapiens	5-deazaacyclotetrahydrofolate	—	0.0053	—	37 °C	PMID 8662720	Open record: cytosolic folylpolyglutamate synthetase (FPGS), 5-deazaacyclotetrahydrofolate
cytosolic folylpolyglutamate synthetase (FPGS)	Homo sapiens	aminopterin	—	0.0044	—	37 °C	PMID 8662720	Open record: cytosolic folylpolyglutamate synthetase (FPGS), aminopterin
cytosolic folylpolyglutamate synthetase (FPGS)	Homo sapiens	dihydropteroyldi-γ-glutamate	—	0.047	—	37 °C	PMID 8662720	Open record: cytosolic folylpolyglutamate synthetase (FPGS), dihydropteroyldi-γ-glutamate
cytosolic folylpolyglutamate synthetase (FPGS)	Homo sapiens	dihydropteroylglutamic acid (dihydrofolate)	—	8.1 × 10⁻⁴	—	37 °C	PMID 8662720	Open record: cytosolic folylpolyglutamate synthetase (FPGS), dihydropteroylglutamic acid (dihydrofolate)
cytosolic folylpolyglutamate synthetase (FPGS)	Homo sapiens	L-glutamate	—	0.201	—	37 °C	PMID 8662720	Open record: cytosolic folylpolyglutamate synthetase (FPGS), L-glutamate
cytosolic folylpolyglutamate synthetase (FPGS)	Homo sapiens	methotrexate	—	0.071	—	37 °C	PMID 8662720	Open record: cytosolic folylpolyglutamate synthetase (FPGS), methotrexate
cytosolic folylpolyglutamate synthetase (FPGS)	Homo sapiens	methotrexate diglutamate (methotrexate-γ-glutamate)	—	0.05	—	37 °C	PMID 8662720	Open record: cytosolic folylpolyglutamate synthetase (FPGS), methotrexate diglutamate (methotrexate-γ-glutamate)
cytosolic folylpolyglutamate synthetase (FPGS)	Homo sapiens	methotrexate triglutamate	—	0.148	—	37 °C	PMID 8662720	Open record: cytosolic folylpolyglutamate synthetase (FPGS), methotrexate triglutamate
cytosolic folylpolyglutamate synthetase (FPGS)	Homo sapiens	MgATP	—	0.2	—	37 °C	PMID 8662720	Open record: cytosolic folylpolyglutamate synthetase (FPGS), MgATP
cytosolic folylpolyglutamate synthetase (FPGS)	Homo sapiens	MgATPwith 10 mM sodium bicarbonate	—	0.054	—	37 °C	PMID 8662720	Open record: cytosolic folylpolyglutamate synthetase (FPGS), MgATP
cytosolic folylpolyglutamate synthetase (FPGS)	Homo sapiens	pteroyldi-γ-glutamate	—	0.016	—	37 °C	PMID 8662720	Open record: cytosolic folylpolyglutamate synthetase (FPGS), pteroyldi-γ-glutamate
cytosolic folylpolyglutamate synthetase (FPGS)	Homo sapiens	pteroylglutamic acid (folic acid)	—	0.059	—	37 °C	PMID 8662720	Open record: cytosolic folylpolyglutamate synthetase (FPGS), pteroylglutamic acid (folic acid)
cytosolic folylpolyglutamate synthetase (FPGS)	Homo sapiens	pteroylpenta-γ-glutamate	—	0.064	—	37 °C	PMID 8662720	Open record: cytosolic folylpolyglutamate synthetase (FPGS), pteroylpenta-γ-glutamate
cytosolic folylpolyglutamate synthetase (FPGS)	Homo sapiens	pteroyltetra-γ-glutamate	—	0.012	—	37 °C	PMID 8662720	Open record: cytosolic folylpolyglutamate synthetase (FPGS), pteroyltetra-γ-glutamate
cytosolic folylpolyglutamate synthetase (FPGS)	Homo sapiens	pteroyltri-γ-glutamate	—	0.02	—	37 °C	PMID 8662720	Open record: cytosolic folylpolyglutamate synthetase (FPGS), pteroyltri-γ-glutamate
dihydrofolate synthase–folylpolyglutamate synthase (FPGS activity)	Plasmodium falciparum	5,6,7,8-tetrahydrofolate	—	9.6 × 10⁻⁴	—	pH 10, 37 °C	PMID 20350571	Open record: dihydrofolate synthase–folylpolyglutamate synthase (FPGS activity), 5,6,7,8-tetrahydrofolate
folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS)	Homo sapiens	adenosine 5'-triphosphate	—	0.046	—	pH 8.9, 37 °C	PMID 10480915	Open record: folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS), adenosine 5'-triphosphate
folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS)	Homo sapiens	aminopterin	0.45	0.009	50 calc.	pH 8.9, 37 °C	PMID 10480915	Open record: folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS), aminopterin
folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS)	Homo sapiens	glutamic acid	—	0.235	—	pH 8.9, 37 °C	PMID 10480915	Open record: folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS), glutamic acid
folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS)variant C346A	Homo sapiens	adenosine 5'-triphosphate	—	0.04	—	pH 8.9, 37 °C	PMID 10480915	Open record: folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS) variant C346A, adenosine 5'-triphosphate
folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS)variant C346A	Homo sapiens	aminopterin	0.53	0.013	41 calc.	pH 8.9, 37 °C	PMID 10480915	Open record: folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS) variant C346A, aminopterin
folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS)variant C346A	Homo sapiens	glutamic acid	—	0.52	—	pH 8.9, 37 °C	PMID 10480915	Open record: folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS) variant C346A, glutamic acid
folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS)variant D335A	Homo sapiens	adenosine 5'-triphosphate	—	0.267	—	pH 8.9, 37 °C	PMID 10480915	Open record: folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS) variant D335A, adenosine 5'-triphosphate
folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS)variant D335A	Homo sapiens	aminopterin	0.42	0.18	2.3 calc.	pH 8.9, 37 °C	PMID 10480915	Open record: folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS) variant D335A, aminopterin
folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS)variant D335A	Homo sapiens	glutamic acid	—	91	—	pH 8.9, 37 °C	PMID 10480915	Open record: folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS) variant D335A, glutamic acid
folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS)variant D376A	Homo sapiens	adenosine 5'-triphosphate	—	0.028	—	pH 8.9, 37 °C	PMID 10480915	Open record: folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS) variant D376A, adenosine 5'-triphosphate
folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS)variant D376A	Homo sapiens	aminopterin	0.55	0.031	18 calc.	pH 8.9, 37 °C	PMID 10480915	Open record: folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS) variant D376A, aminopterin
folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS)variant D376A	Homo sapiens	glutamic acid	—	2.9	—	pH 8.9, 37 °C	PMID 10480915	Open record: folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS) variant D376A, glutamic acid
folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS)variant D378A	Homo sapiens	adenosine 5'-triphosphate	—	0.06	—	pH 8.9, 37 °C	PMID 10480915	Open record: folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS) variant D378A, adenosine 5'-triphosphate
folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS)variant D378A	Homo sapiens	aminopterin	0.63	0.017	37 calc.	pH 8.9, 37 °C	PMID 10480915	Open record: folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS) variant D378A, aminopterin
folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS)variant D378A	Homo sapiens	glutamic acid	—	0.83	—	pH 8.9, 37 °C	PMID 10480915	Open record: folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS) variant D378A, glutamic acid
folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS)variant H338A	Homo sapiens	adenosine 5'-triphosphate	—	0.016	—	pH 8.9, 37 °C	PMID 10480915	Open record: folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS) variant H338A, adenosine 5'-triphosphate
folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS)variant H338A	Homo sapiens	aminopterin	0.24	0.0065	37 calc.	pH 8.9, 37 °C	PMID 10480915	Open record: folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS) variant H338A, aminopterin
folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS)variant H338A	Homo sapiens	glutamic acid	—	140	—	pH 8.9, 37 °C	PMID 10480915	Open record: folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS) variant H338A, glutamic acid
folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS)variant K384A	Homo sapiens	adenosine 5'-triphosphate	—	0.045	—	pH 8.9, 37 °C	PMID 10480915	Open record: folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS) variant K384A, adenosine 5'-triphosphate
folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS)variant K384A	Homo sapiens	aminopterin	0.67	0.011	61 calc.	pH 8.9, 37 °C	PMID 10480915	Open record: folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS) variant K384A, aminopterin
folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS)variant K384A	Homo sapiens	glutamic acid	—	0.43	—	pH 8.9, 37 °C	PMID 10480915	Open record: folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS) variant K384A, glutamic acid
folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS)variant R377A	Homo sapiens	adenosine 5'-triphosphate	—	0.0046	—	pH 8.9, 37 °C	PMID 10480915	Open record: folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS) variant R377A, adenosine 5'-triphosphate
folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS)variant R377A	Homo sapiens	aminopterin	0.025	0.0059	4.2 calc.	pH 8.9, 37 °C	PMID 10480915	Open record: folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS) variant R377A, aminopterin
folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS)variant R377A	Homo sapiens	glutamic acid	—	350	—	pH 8.9, 37 °C	PMID 10480915	Open record: folylpoly-γ-glutamate synthetase, cytosolic form (rhcFPGS) variant R377A, glutamic acid
folylpolyglutamate synthase (FPGS), cytosolic isozyme	Homo sapiens	(6R)-10-formyltetrahydropteroyldi-γ-glutamate	0.3	0.0027	110	pH 9.75, 37 °C	PMID 9250977	Open record: folylpolyglutamate synthase (FPGS), cytosolic isozyme, (6R)-10-formyltetrahydropteroyldi-γ-glutamate
folylpolyglutamate synthase (FPGS), cytosolic isozyme	Homo sapiens	(6R)-10-formyltetrahydropteroylglutamate	0.23	0.0037	61	pH 9.75, 37 °C	PMID 9250977	Open record: folylpolyglutamate synthase (FPGS), cytosolic isozyme, (6R)-10-formyltetrahydropteroylglutamate
folylpolyglutamate synthase (FPGS), cytosolic isozyme	Homo sapiens	(6R,S)-tetrahydropteroylglutamate	0.82	0.0016	518	pH 9.75, 37 °C	PMID 9250977	Open record: folylpolyglutamate synthase (FPGS), cytosolic isozyme, (6R,S)-tetrahydropteroylglutamate
folylpolyglutamate synthase (FPGS), cytosolic isozyme	Homo sapiens	(6S)-5-formyltetrahydropteroyldi-γ-glutamate	0.67	0.013	52	pH 9.75, 37 °C	PMID 9250977	Open record: folylpolyglutamate synthase (FPGS), cytosolic isozyme, (6S)-5-formyltetrahydropteroyldi-γ-glutamate
folylpolyglutamate synthase (FPGS), cytosolic isozyme	Homo sapiens	(6S)-5-formyltetrahydropteroylglutamate	0.84	0.105	8.1	pH 9.75, 37 °C	PMID 9250977	Open record: folylpolyglutamate synthase (FPGS), cytosolic isozyme, (6S)-5-formyltetrahydropteroylglutamate
folylpolyglutamate synthase (FPGS), cytosolic isozyme	Homo sapiens	(6S)-5-methyltetrahydropteroylglutamate	0.82	0.048	17	pH 9.75, 37 °C	PMID 9250977	Open record: folylpolyglutamate synthase (FPGS), cytosolic isozyme, (6S)-5-methyltetrahydropteroylglutamate
folylpolyglutamate synthase (FPGS), cytosolic isozyme	Homo sapiens	(6S)-tetrahydropteroyldi-γ-glutamate	0.81	0.0033	245	pH 9.75, 37 °C	PMID 9250977	Open record: folylpolyglutamate synthase (FPGS), cytosolic isozyme, (6S)-tetrahydropteroyldi-γ-glutamate
folylpolyglutamate synthase (FPGS), cytosolic isozyme	Homo sapiens	(6S)-tetrahydropteroylglutamate	0.99	0.0044	225	pH 9.75, 37 °C	PMID 9250977	Open record: folylpolyglutamate synthase (FPGS), cytosolic isozyme, (6S)-tetrahydropteroylglutamate
folylpolyglutamate synthase (FPGS), cytosolic isozyme	Homo sapiens	(6S)-tetrahydropteroylpenta-γ-glutamate	0.006	0.0014	4.3	pH 9.75, 37 °C	PMID 9250977	Open record: folylpolyglutamate synthase (FPGS), cytosolic isozyme, (6S)-tetrahydropteroylpenta-γ-glutamate
folylpolyglutamate synthase (FPGS), cytosolic isozyme	Homo sapiens	(6S)-tetrahydropteroyltetra-γ-glutamate	0.1	0.0016	65	pH 9.75, 37 °C	PMID 9250977	Open record: folylpolyglutamate synthase (FPGS), cytosolic isozyme, (6S)-tetrahydropteroyltetra-γ-glutamate
folylpolyglutamate synthase (FPGS), cytosolic isozyme	Homo sapiens	(6S)-tetrahydropteroyltri-γ-glutamate	0.19	0.0014	135	pH 9.75, 37 °C	PMID 9250977	Open record: folylpolyglutamate synthase (FPGS), cytosolic isozyme, (6S)-tetrahydropteroyltri-γ-glutamate
folylpolyglutamate synthase (FPGS), cytosolic isozyme	Homo sapiens	aminopterin	1.17	0.0044	266	pH 9.75, 37 °C	PMID 9250977	Open record: folylpolyglutamate synthase (FPGS), cytosolic isozyme, aminopterin
folylpolyglutamate synthase (FPGS), cytosolic isozyme	Homo sapiens	dihydropteroyldi-γ-glutamate	0.95	0.047	19	pH 9.75, 37 °C	PMID 9250977	Open record: folylpolyglutamate synthase (FPGS), cytosolic isozyme, dihydropteroyldi-γ-glutamate
folylpolyglutamate synthase (FPGS), cytosolic isozyme	Homo sapiens	dihydropteroylglutamate	0.84	8.1 × 10⁻⁴	1035	pH 9.75, 37 °C	PMID 9250977	Open record: folylpolyglutamate synthase (FPGS), cytosolic isozyme, dihydropteroylglutamate
folylpolyglutamate synthase (FPGS), cytosolic isozyme	Homo sapiens	L-glutamate	—	0.2	—	pH 9.6, 37 °C	PMID 9250977	Open record: folylpolyglutamate synthase (FPGS), cytosolic isozyme, L-glutamate
folylpolyglutamate synthase (FPGS), cytosolic isozyme	Homo sapiens	methotrexate	0.93	0.071	13	pH 9.75, 37 °C	PMID 9250977	Open record: folylpolyglutamate synthase (FPGS), cytosolic isozyme, methotrexate
folylpolyglutamate synthase (FPGS), cytosolic isozyme	Homo sapiens	methotrexate diglutamate	0.16	0.05	3.2	pH 9.75, 37 °C	PMID 9250977	Open record: folylpolyglutamate synthase (FPGS), cytosolic isozyme, methotrexate diglutamate
folylpolyglutamate synthase (FPGS), cytosolic isozyme	Homo sapiens	methotrexate triglutamate	0.032	0.148	0.19	pH 9.75, 37 °C	PMID 9250977	Open record: folylpolyglutamate synthase (FPGS), cytosolic isozyme, methotrexate triglutamate
folylpolyglutamate synthase (FPGS), cytosolic isozyme	Homo sapiens	MgATP	—	0.2	—	pH 9.6, 37 °C	PMID 9250977	Open record: folylpolyglutamate synthase (FPGS), cytosolic isozyme, MgATP
folylpolyglutamate synthase (FPGS), cytosolic isozyme	Homo sapiens	pteroyldi-γ-glutamate	0.82	0.016	52	pH 9.75, 37 °C	PMID 9250977	Open record: folylpolyglutamate synthase (FPGS), cytosolic isozyme, pteroyldi-γ-glutamate
folylpolyglutamate synthase (FPGS), cytosolic isozyme	Homo sapiens	pteroylglutamic acid	0.65	0.059	11	pH 9.75, 37 °C	PMID 9250977	Open record: folylpolyglutamate synthase (FPGS), cytosolic isozyme, pteroylglutamic acid
folylpolyglutamate synthase (FPGS), cytosolic isozyme	Homo sapiens	pteroylpenta-γ-glutamate	0.01	0.064	0.16	pH 9.75, 37 °C	PMID 9250977	Open record: folylpolyglutamate synthase (FPGS), cytosolic isozyme, pteroylpenta-γ-glutamate
folylpolyglutamate synthase (FPGS), cytosolic isozyme	Homo sapiens	pteroyltetra-γ-glutamate	0.34	0.012	29	pH 9.75, 37 °C	PMID 9250977	Open record: folylpolyglutamate synthase (FPGS), cytosolic isozyme, pteroyltetra-γ-glutamate
folylpolyglutamate synthase (FPGS), cytosolic isozyme	Homo sapiens	pteroyltri-γ-glutamate	0.55	0.02	27	pH 9.75, 37 °C	PMID 9250977	Open record: folylpolyglutamate synthase (FPGS), cytosolic isozyme, pteroyltri-γ-glutamate
folylpolyglutamate synthetase (FPGS)	Lactobacillus casei	5,10-methylenetetrahydrofolate	—	0.0315	—	pH 7.5	PMID 10970743	Open record: folylpolyglutamate synthetase (FPGS), 5,10-methylenetetrahydrofolate
folylpolyglutamate synthetase (FPGS)	Lactobacillus casei	adenosine 5'-triphosphate	—	3.4	—	pH 7.5	PMID 10970743	Open record: folylpolyglutamate synthetase (FPGS), adenosine 5'-triphosphate
folylpolyglutamate synthetase (FPGS)	Lactobacillus casei	L-glutamate	—	0.47	—	pH 7.5	PMID 10970743	Open record: folylpolyglutamate synthetase (FPGS), L-glutamate
folylpolyglutamate synthetase (FPGS)variant E81A	Lactobacillus casei	5,10-methylenetetrahydrofolate	—	0.071	—	pH 7.5	PMID 10970743	Open record: folylpolyglutamate synthetase (FPGS) variant E81A, 5,10-methylenetetrahydrofolate
folylpolyglutamate synthetase (FPGS)variant E81A	Lactobacillus casei	adenosine 5'-triphosphate	—	5.2	—	pH 7.5	PMID 10970743	Open record: folylpolyglutamate synthetase (FPGS) variant E81A, adenosine 5'-triphosphate
folylpolyglutamate synthetase (FPGS)variant E81A	Lactobacillus casei	L-glutamate	—	0.41	—	pH 7.5	PMID 10970743	Open record: folylpolyglutamate synthetase (FPGS) variant E81A, L-glutamate
folylpolyglutamate synthetase (FPGS)variant K185A	Lactobacillus casei	5,10-methylenetetrahydrofolate	—	0.24	—	pH 7.5	PMID 10970743	Open record: folylpolyglutamate synthetase (FPGS) variant K185A, 5,10-methylenetetrahydrofolate
folylpolyglutamate synthetase (FPGS)variant K185A	Lactobacillus casei	adenosine 5'-triphosphate	—	2.9	—	pH 7.5	PMID 10970743	Open record: folylpolyglutamate synthetase (FPGS) variant K185A, adenosine 5'-triphosphate
folylpolyglutamate synthetase (FPGS)variant K185A	Lactobacillus casei	L-glutamate	—	5.06	—	pH 7.5	PMID 10970743	Open record: folylpolyglutamate synthetase (FPGS) variant K185A, L-glutamate
folylpolyglutamate synthetase (FPGS)variant R82A	Lactobacillus casei	5,10-methylenetetrahydrofolate	—	0.21	—	pH 7.5	PMID 10970743	Open record: folylpolyglutamate synthetase (FPGS) variant R82A, 5,10-methylenetetrahydrofolate
folylpolyglutamate synthetase (FPGS)variant R82A	Lactobacillus casei	adenosine 5'-triphosphate	—	0.87	—	pH 7.5	PMID 10970743	Open record: folylpolyglutamate synthetase (FPGS) variant R82A, adenosine 5'-triphosphate
folylpolyglutamate synthetase (FPGS)variant R82A	Lactobacillus casei	L-glutamate	—	2.06	—	pH 7.5	PMID 10970743	Open record: folylpolyglutamate synthetase (FPGS) variant R82A, L-glutamate
folylpolyglutamate synthetase (FPGS)variant S412A	Lactobacillus casei	5,10-methylenetetrahydrofolate	—	0.094	—	pH 7.5	PMID 10970743	Open record: folylpolyglutamate synthetase (FPGS) variant S412A, 5,10-methylenetetrahydrofolate
folylpolyglutamate synthetase (FPGS)variant S412A	Lactobacillus casei	adenosine 5'-triphosphate	—	0.62	—	pH 7.5	PMID 10970743	Open record: folylpolyglutamate synthetase (FPGS) variant S412A, adenosine 5'-triphosphate
folylpolyglutamate synthetase (FPGS)variant S412A	Lactobacillus casei	L-glutamate	—	26.69	—	pH 7.5	PMID 10970743	Open record: folylpolyglutamate synthetase (FPGS) variant S412A, L-glutamate
folylpolyglutamate synthetase (FPGS)variant S73A	Lactobacillus casei	5,10-methylenetetrahydrofolate	—	0.655	—	pH 7.5	PMID 10970743	Open record: folylpolyglutamate synthetase (FPGS) variant S73A, 5,10-methylenetetrahydrofolate
folylpolyglutamate synthetase (FPGS)variant S73A	Lactobacillus casei	adenosine 5'-triphosphate	—	2.5	—	pH 7.5	PMID 10970743	Open record: folylpolyglutamate synthetase (FPGS) variant S73A, adenosine 5'-triphosphate
folylpolyglutamate synthetase (FPGS)variant S73A	Lactobacillus casei	L-glutamate	—	0.85	—	pH 7.5	PMID 10970743	Open record: folylpolyglutamate synthetase (FPGS) variant S73A, L-glutamate