Values CatLog read from this paper

Purification and properties of human cytosolic folylpoly-gamma-glutamate synthetase and organization, localization, and differential splicing of its gene

PMID 8662720doi:10.1074/jbc.271.22.13077Open in Browse

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CatLog read 27 records (29 values) from this paper: cytosolic folylpolyglutamate synthetase (FPGS) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 6.3.2.17

Records read from this paper
EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsOpen record
cytosolic folylpolyglutamate synthetase (FPGS)Homo sapiens(6R)-10-formyltetrahydropteroyldi-γ-glutamate—0.0027—37 °COpen record: cytosolic folylpolyglutamate synthetase (FPGS), (6R)-10-formyltetrahydropteroyldi-γ-glutamate
cytosolic folylpolyglutamate synthetase (FPGS)Homo sapiens(6R)-10-formyltetrahydropteroylglutamic acid ((6R)-10-formyltetrahydrofolate)—0.0037—37 °COpen record: cytosolic folylpolyglutamate synthetase (FPGS), (6R)-10-formyltetrahydropteroylglutamic acid ((6R)-10-formyltetrahydrofolate)
cytosolic folylpolyglutamate synthetase (FPGS)Homo sapiens(6RS)-tetrahydropteroylglutamic acid ((6RS)-tetrahydrofolate)—0.0016—37 °COpen record: cytosolic folylpolyglutamate synthetase (FPGS), (6RS)-tetrahydropteroylglutamic acid ((6RS)-tetrahydrofolate)
cytosolic folylpolyglutamate synthetase (FPGS)Homo sapiens(6S)-5-formyltetrahydrofolate (folinate)—0.105—37 °COpen record: cytosolic folylpolyglutamate synthetase (FPGS), (6S)-5-formyltetrahydrofolate (folinate)
cytosolic folylpolyglutamate synthetase (FPGS)Homo sapiens(6S)-5-formyltetrahydropteroyldi-γ-glutamate—0.013—37 °COpen record: cytosolic folylpolyglutamate synthetase (FPGS), (6S)-5-formyltetrahydropteroyldi-γ-glutamate
cytosolic folylpolyglutamate synthetase (FPGS)Homo sapiens(6S)-5-methyltetrahydropteroylglutamic acid ((6S)-5-methyltetrahydrofolate)—0.048—37 °COpen record: cytosolic folylpolyglutamate synthetase (FPGS), (6S)-5-methyltetrahydropteroylglutamic acid ((6S)-5-methyltetrahydrofolate)
cytosolic folylpolyglutamate synthetase (FPGS)Homo sapiens(6S)-tetrahydropteroyldi-γ-glutamate—0.0033—37 °COpen record: cytosolic folylpolyglutamate synthetase (FPGS), (6S)-tetrahydropteroyldi-γ-glutamate
cytosolic folylpolyglutamate synthetase (FPGS)Homo sapiens(6S)-tetrahydropteroylglutamic acid ((6S)-tetrahydrofolate)0.990.004422537 °COpen record: cytosolic folylpolyglutamate synthetase (FPGS), (6S)-tetrahydropteroylglutamic acid ((6S)-tetrahydrofolate)
cytosolic folylpolyglutamate synthetase (FPGS)Homo sapiens(6S)-tetrahydropteroylpenta-γ-glutamate—0.0014—37 °COpen record: cytosolic folylpolyglutamate synthetase (FPGS), (6S)-tetrahydropteroylpenta-γ-glutamate
cytosolic folylpolyglutamate synthetase (FPGS)Homo sapiens(6S)-tetrahydropteroyltetra-γ-glutamate—0.0016—37 °COpen record: cytosolic folylpolyglutamate synthetase (FPGS), (6S)-tetrahydropteroyltetra-γ-glutamate
cytosolic folylpolyglutamate synthetase (FPGS)Homo sapiens(6S)-tetrahydropteroyltri-γ-glutamate—0.0014—37 °COpen record: cytosolic folylpolyglutamate synthetase (FPGS), (6S)-tetrahydropteroyltri-γ-glutamate
cytosolic folylpolyglutamate synthetase (FPGS)Homo sapiens2-methyl-5,8-dideazaisofolate—0.0028—37 °COpen record: cytosolic folylpolyglutamate synthetase (FPGS), 2-methyl-5,8-dideazaisofolate
cytosolic folylpolyglutamate synthetase (FPGS)Homo sapiens5-deazaacyclotetrahydrofolate—0.0053—37 °COpen record: cytosolic folylpolyglutamate synthetase (FPGS), 5-deazaacyclotetrahydrofolate
cytosolic folylpolyglutamate synthetase (FPGS)Homo sapiensaminopterin—0.0044—37 °COpen record: cytosolic folylpolyglutamate synthetase (FPGS), aminopterin
cytosolic folylpolyglutamate synthetase (FPGS)Homo sapiensdihydropteroyldi-γ-glutamate—0.047—37 °COpen record: cytosolic folylpolyglutamate synthetase (FPGS), dihydropteroyldi-γ-glutamate
cytosolic folylpolyglutamate synthetase (FPGS)Homo sapiensdihydropteroylglutamic acid (dihydrofolate)—8.1 × 10⁻⁴—37 °COpen record: cytosolic folylpolyglutamate synthetase (FPGS), dihydropteroylglutamic acid (dihydrofolate)
cytosolic folylpolyglutamate synthetase (FPGS)Homo sapiensL-glutamate—0.201—37 °COpen record: cytosolic folylpolyglutamate synthetase (FPGS), L-glutamate
cytosolic folylpolyglutamate synthetase (FPGS)Homo sapiensmethotrexate—0.071—37 °COpen record: cytosolic folylpolyglutamate synthetase (FPGS), methotrexate
cytosolic folylpolyglutamate synthetase (FPGS)Homo sapiensmethotrexate diglutamate (methotrexate-γ-glutamate)—0.05—37 °COpen record: cytosolic folylpolyglutamate synthetase (FPGS), methotrexate diglutamate (methotrexate-γ-glutamate)
cytosolic folylpolyglutamate synthetase (FPGS)Homo sapiensmethotrexate triglutamate—0.148—37 °COpen record: cytosolic folylpolyglutamate synthetase (FPGS), methotrexate triglutamate
cytosolic folylpolyglutamate synthetase (FPGS)Homo sapiensMgATP—0.2—37 °COpen record: cytosolic folylpolyglutamate synthetase (FPGS), MgATP
cytosolic folylpolyglutamate synthetase (FPGS)Homo sapiensMgATPwith 10 mM sodium bicarbonate—0.054—37 °COpen record: cytosolic folylpolyglutamate synthetase (FPGS), MgATP
cytosolic folylpolyglutamate synthetase (FPGS)Homo sapienspteroyldi-γ-glutamate—0.016—37 °COpen record: cytosolic folylpolyglutamate synthetase (FPGS), pteroyldi-γ-glutamate
cytosolic folylpolyglutamate synthetase (FPGS)Homo sapienspteroylglutamic acid (folic acid)—0.059—37 °COpen record: cytosolic folylpolyglutamate synthetase (FPGS), pteroylglutamic acid (folic acid)
cytosolic folylpolyglutamate synthetase (FPGS)Homo sapienspteroylpenta-γ-glutamate—0.064—37 °COpen record: cytosolic folylpolyglutamate synthetase (FPGS), pteroylpenta-γ-glutamate
cytosolic folylpolyglutamate synthetase (FPGS)Homo sapienspteroyltetra-γ-glutamate—0.012—37 °COpen record: cytosolic folylpolyglutamate synthetase (FPGS), pteroyltetra-γ-glutamate
cytosolic folylpolyglutamate synthetase (FPGS)Homo sapienspteroyltri-γ-glutamate—0.02—37 °COpen record: cytosolic folylpolyglutamate synthetase (FPGS), pteroyltri-γ-glutamate