Values CatLog read from this paper
Purification and properties of human cytosolic folylpoly-gamma-glutamate synthetase and organization, localization, and differential splicing of its gene
PMID 8662720doi:10.1074/jbc.271.22.13077Open in Browse
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CatLog read 27 records (29 values) from this paper: cytosolic folylpolyglutamate synthetase (FPGS) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| cytosolic folylpolyglutamate synthetase (FPGS) | Homo sapiens | (6R)-10-formyltetrahydropteroyldi-γ-glutamate | — | 0.0027 | — | 37 °C | Open record: cytosolic folylpolyglutamate synthetase (FPGS), (6R)-10-formyltetrahydropteroyldi-γ-glutamate |
| cytosolic folylpolyglutamate synthetase (FPGS) | Homo sapiens | (6R)-10-formyltetrahydropteroylglutamic acid ((6R)-10-formyltetrahydrofolate) | — | 0.0037 | — | 37 °C | Open record: cytosolic folylpolyglutamate synthetase (FPGS), (6R)-10-formyltetrahydropteroylglutamic acid ((6R)-10-formyltetrahydrofolate) |
| cytosolic folylpolyglutamate synthetase (FPGS) | Homo sapiens | (6RS)-tetrahydropteroylglutamic acid ((6RS)-tetrahydrofolate) | — | 0.0016 | — | 37 °C | Open record: cytosolic folylpolyglutamate synthetase (FPGS), (6RS)-tetrahydropteroylglutamic acid ((6RS)-tetrahydrofolate) |
| cytosolic folylpolyglutamate synthetase (FPGS) | Homo sapiens | (6S)-5-formyltetrahydrofolate (folinate) | — | 0.105 | — | 37 °C | Open record: cytosolic folylpolyglutamate synthetase (FPGS), (6S)-5-formyltetrahydrofolate (folinate) |
| cytosolic folylpolyglutamate synthetase (FPGS) | Homo sapiens | (6S)-5-formyltetrahydropteroyldi-γ-glutamate | — | 0.013 | — | 37 °C | Open record: cytosolic folylpolyglutamate synthetase (FPGS), (6S)-5-formyltetrahydropteroyldi-γ-glutamate |
| cytosolic folylpolyglutamate synthetase (FPGS) | Homo sapiens | (6S)-5-methyltetrahydropteroylglutamic acid ((6S)-5-methyltetrahydrofolate) | — | 0.048 | — | 37 °C | Open record: cytosolic folylpolyglutamate synthetase (FPGS), (6S)-5-methyltetrahydropteroylglutamic acid ((6S)-5-methyltetrahydrofolate) |
| cytosolic folylpolyglutamate synthetase (FPGS) | Homo sapiens | (6S)-tetrahydropteroyldi-γ-glutamate | — | 0.0033 | — | 37 °C | Open record: cytosolic folylpolyglutamate synthetase (FPGS), (6S)-tetrahydropteroyldi-γ-glutamate |
| cytosolic folylpolyglutamate synthetase (FPGS) | Homo sapiens | (6S)-tetrahydropteroylglutamic acid ((6S)-tetrahydrofolate) | 0.99 | 0.0044 | 225 | 37 °C | Open record: cytosolic folylpolyglutamate synthetase (FPGS), (6S)-tetrahydropteroylglutamic acid ((6S)-tetrahydrofolate) |
| cytosolic folylpolyglutamate synthetase (FPGS) | Homo sapiens | (6S)-tetrahydropteroylpenta-γ-glutamate | — | 0.0014 | — | 37 °C | Open record: cytosolic folylpolyglutamate synthetase (FPGS), (6S)-tetrahydropteroylpenta-γ-glutamate |
| cytosolic folylpolyglutamate synthetase (FPGS) | Homo sapiens | (6S)-tetrahydropteroyltetra-γ-glutamate | — | 0.0016 | — | 37 °C | Open record: cytosolic folylpolyglutamate synthetase (FPGS), (6S)-tetrahydropteroyltetra-γ-glutamate |
| cytosolic folylpolyglutamate synthetase (FPGS) | Homo sapiens | (6S)-tetrahydropteroyltri-γ-glutamate | — | 0.0014 | — | 37 °C | Open record: cytosolic folylpolyglutamate synthetase (FPGS), (6S)-tetrahydropteroyltri-γ-glutamate |
| cytosolic folylpolyglutamate synthetase (FPGS) | Homo sapiens | 2-methyl-5,8-dideazaisofolate | — | 0.0028 | — | 37 °C | Open record: cytosolic folylpolyglutamate synthetase (FPGS), 2-methyl-5,8-dideazaisofolate |
| cytosolic folylpolyglutamate synthetase (FPGS) | Homo sapiens | 5-deazaacyclotetrahydrofolate | — | 0.0053 | — | 37 °C | Open record: cytosolic folylpolyglutamate synthetase (FPGS), 5-deazaacyclotetrahydrofolate |
| cytosolic folylpolyglutamate synthetase (FPGS) | Homo sapiens | aminopterin | — | 0.0044 | — | 37 °C | Open record: cytosolic folylpolyglutamate synthetase (FPGS), aminopterin |
| cytosolic folylpolyglutamate synthetase (FPGS) | Homo sapiens | dihydropteroyldi-γ-glutamate | — | 0.047 | — | 37 °C | Open record: cytosolic folylpolyglutamate synthetase (FPGS), dihydropteroyldi-γ-glutamate |
| cytosolic folylpolyglutamate synthetase (FPGS) | Homo sapiens | dihydropteroylglutamic acid (dihydrofolate) | — | 8.1 × 10⁻⁴ | — | 37 °C | Open record: cytosolic folylpolyglutamate synthetase (FPGS), dihydropteroylglutamic acid (dihydrofolate) |
| cytosolic folylpolyglutamate synthetase (FPGS) | Homo sapiens | L-glutamate | — | 0.201 | — | 37 °C | Open record: cytosolic folylpolyglutamate synthetase (FPGS), L-glutamate |
| cytosolic folylpolyglutamate synthetase (FPGS) | Homo sapiens | methotrexate | — | 0.071 | — | 37 °C | Open record: cytosolic folylpolyglutamate synthetase (FPGS), methotrexate |
| cytosolic folylpolyglutamate synthetase (FPGS) | Homo sapiens | methotrexate diglutamate (methotrexate-γ-glutamate) | — | 0.05 | — | 37 °C | Open record: cytosolic folylpolyglutamate synthetase (FPGS), methotrexate diglutamate (methotrexate-γ-glutamate) |
| cytosolic folylpolyglutamate synthetase (FPGS) | Homo sapiens | methotrexate triglutamate | — | 0.148 | — | 37 °C | Open record: cytosolic folylpolyglutamate synthetase (FPGS), methotrexate triglutamate |
| cytosolic folylpolyglutamate synthetase (FPGS) | Homo sapiens | MgATP | — | 0.2 | — | 37 °C | Open record: cytosolic folylpolyglutamate synthetase (FPGS), MgATP |
| cytosolic folylpolyglutamate synthetase (FPGS) | Homo sapiens | MgATPwith 10 mM sodium bicarbonate | — | 0.054 | — | 37 °C | Open record: cytosolic folylpolyglutamate synthetase (FPGS), MgATP |
| cytosolic folylpolyglutamate synthetase (FPGS) | Homo sapiens | pteroyldi-γ-glutamate | — | 0.016 | — | 37 °C | Open record: cytosolic folylpolyglutamate synthetase (FPGS), pteroyldi-γ-glutamate |
| cytosolic folylpolyglutamate synthetase (FPGS) | Homo sapiens | pteroylglutamic acid (folic acid) | — | 0.059 | — | 37 °C | Open record: cytosolic folylpolyglutamate synthetase (FPGS), pteroylglutamic acid (folic acid) |
| cytosolic folylpolyglutamate synthetase (FPGS) | Homo sapiens | pteroylpenta-γ-glutamate | — | 0.064 | — | 37 °C | Open record: cytosolic folylpolyglutamate synthetase (FPGS), pteroylpenta-γ-glutamate |
| cytosolic folylpolyglutamate synthetase (FPGS) | Homo sapiens | pteroyltetra-γ-glutamate | — | 0.012 | — | 37 °C | Open record: cytosolic folylpolyglutamate synthetase (FPGS), pteroyltetra-γ-glutamate |
| cytosolic folylpolyglutamate synthetase (FPGS) | Homo sapiens | pteroyltri-γ-glutamate | — | 0.02 | — | 37 °C | Open record: cytosolic folylpolyglutamate synthetase (FPGS), pteroyltri-γ-glutamate |