Values CatLog read from this paper

Specificity of S'1 and S'2 subsites of human tissue kallikrein using the reactive-centre loop of kallistatin: the importance of P'1 and P'2 positions in design of inhibitors

PMID 12578561doi:10.1042/bj20021952Open in Browse

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CatLog read 8 records (24 values) from this paper: human tissue kallikrein (hK1) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.4.21.35

Records read from this paper
EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsOpen record
human tissue kallikrein (hK1)Homo sapienso-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Gln-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine0.021.3 × 10⁻⁴154pH 9, 37 °COpen record: human tissue kallikrein (hK1), o-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Gln-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
human tissue kallikrein (hK1)Homo sapienso-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Ile-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine0.052.7 × 10⁻⁴185pH 9, 37 °COpen record: human tissue kallikrein (hK1), o-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Ile-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
human tissue kallikrein (hK1)Homo sapienso-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Ser-Ala-Gln-N-(2,4-dinitrophenyl)ethylenediamine0.540.00179302pH 9, 37 °COpen record: human tissue kallikrein (hK1), o-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Ser-Ala-Gln-N-(2,4-dinitrophenyl)ethylenediamine
human tissue kallikrein (hK1)Homo sapienso-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Ser-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine3.333.6 × 10⁻⁴9.25 × 10³pH 9, 37 °COpen record: human tissue kallikrein (hK1), o-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Ser-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
human tissue kallikrein (hK1)Homo sapienso-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine0.122.1 × 10⁻⁴571pH 9, 37 °COpen record: human tissue kallikrein (hK1), o-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Ser-Lys-Gln-N-(2,4-dinitrophenyl)ethylenediamine
human tissue kallikrein (hK1)Homo sapienso-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Ser-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine0.050.0012540pH 9, 37 °COpen record: human tissue kallikrein (hK1), o-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Ser-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine
human tissue kallikrein (hK1)Homo sapienso-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Ser-Ser-Gln-N-(2,4-dinitrophenyl)ethylenediamine0.39.4 × 10⁻⁴319pH 9, 37 °COpen record: human tissue kallikrein (hK1), o-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Ser-Ser-Gln-N-(2,4-dinitrophenyl)ethylenediamine
human tissue kallikrein (hK1)Homo sapienso-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Thr-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine0.042.3 × 10⁻⁴174pH 9, 37 °COpen record: human tissue kallikrein (hK1), o-aminobenzoyl-Ala-Ile-Lys-Phe-Phe-Thr-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine