Values CatLog read from this paper
The mechanism of action of the fragile histidine triad, Fhit: isolation of a covalent adenylyl enzyme and chemical rescue of H96G-Fhit
PMID 15182206doi:10.1021/bi049762nOpen in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 6 records (18 values) from this paper: Fhit (fragile histidine triad protein, Ap3A hydrolase) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
EC 2.7.7.51, EC 3.6.1.29, EC 3.6.2.1
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| Fhit (fragile histidine triad protein, Ap3A hydrolase) | Homo sapiens | adenosine-5'-phospho-N-methylimidazolide | 4.2 | 0.0053 | 720 | pH 7.3, 26.5 °C | Open record: Fhit (fragile histidine triad protein, Ap3A hydrolase), adenosine-5'-phospho-N-methylimidazolide |
| Fhit (fragile histidine triad protein, Ap3A hydrolase) | Homo sapiens | adenosine-5'-phosphoimidazolide | 4.4 | 0.0062 | 640 | pH 7, 26.5 °C | Open record: Fhit (fragile histidine triad protein, Ap3A hydrolase), adenosine-5'-phosphoimidazolide |
| Fhit (fragile histidine triad protein, Ap3A hydrolase) | Homo sapiens | P1-5'-O-adenosine-P3-5'-O-adenosine triphosphate | 3.5 | 0.0029 | 1.16 × 10³ | pH 7.3, 26.5 °C | Open record: Fhit (fragile histidine triad protein, Ap3A hydrolase), P1-5'-O-adenosine-P3-5'-O-adenosine triphosphate |
| Fhit (fragile histidine triad protein, Ap3A hydrolase)variant H96G | Homo sapiens | adenosine-5'-phospho-N-methylimidazolide | 0.62 | 0.18 | 1.9 | pH 6.6, 26.5 °C | Open record: Fhit (fragile histidine triad protein, Ap3A hydrolase) variant H96G, adenosine-5'-phospho-N-methylimidazolide |
| Fhit (fragile histidine triad protein, Ap3A hydrolase)variant H96G | Homo sapiens | adenosine-5'-phosphoimidazolide | 0.91 | 0.026 | 35 | pH 5.8, 26.5 °C | Open record: Fhit (fragile histidine triad protein, Ap3A hydrolase) variant H96G, adenosine-5'-phosphoimidazolide |
| Fhit (fragile histidine triad protein, Ap3A hydrolase)variant H96G | Homo sapiens | P1-5'-O-adenosine-P3-5'-O-adenosine triphosphate | 0.0014 | 0.23 | 0.0092 | pH 8.9, 26.5 °C | Open record: Fhit (fragile histidine triad protein, Ap3A hydrolase) variant H96G, P1-5'-O-adenosine-P3-5'-O-adenosine triphosphate |