Values CatLog read from this paper

Crystal structure and pH-dependent allosteric regulation of human β-ureidopropionase, an enzyme involved in anticancer drug metabolism

PMID 29976570doi:10.1042/bcj20180222Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 10 records (10 values) from this paper: β-ureidopropionase (HsβUP) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.6.1.6

Records read from this paper
EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsOpen record
β-ureidopropionase (HsβUP)Homo sapiensN-carbamoyl-β-alanine0.47——pH 6.5, 37 °COpen record: β-ureidopropionase (HsβUP), N-carbamoyl-β-alanine
β-ureidopropionase (HsβUP)Homo sapiensN-carbamoyl-β-alanine—0.048—pH 6.5, 37 °COpen record: β-ureidopropionase (HsβUP), N-carbamoyl-β-alanine
β-ureidopropionase (HsβUP)Homo sapiensN-carbamoyl-β-alanine——9.8pH 6.5, 37 °COpen record: β-ureidopropionase (HsβUP), N-carbamoyl-β-alanine
β-ureidopropionase (HsβUP)Homo sapiensN-carbamoyl-β-alanine5-aminolevulinic acid (5-ALA, competitive inhibitor)0.44——pH 6.5, 37 °COpen record: β-ureidopropionase (HsβUP), N-carbamoyl-β-alanine
β-ureidopropionase (HsβUP)Homo sapiensN-carbamoyl-β-alanine5-aminolevulinic acid (5-ALA, competitive inhibitor)—0.099—pH 6.5, 37 °COpen record: β-ureidopropionase (HsβUP), N-carbamoyl-β-alanine
β-ureidopropionase (HsβUP)Homo sapiensN-carbamoyl-β-alanine5-aminolevulinic acid (5-ALA, competitive inhibitor)——4.5pH 6.5, 37 °COpen record: β-ureidopropionase (HsβUP), N-carbamoyl-β-alanine
β-ureidopropionase (HsβUP)Homo sapiensN-carbamoyl-β-alanineβ-alanine (product, competitive inhibitor)0.5——pH 6.5, 37 °COpen record: β-ureidopropionase (HsβUP), N-carbamoyl-β-alanine
β-ureidopropionase (HsβUP)Homo sapiensN-carbamoyl-β-alanineβ-alanine (product, competitive inhibitor); apparent Km—0.084—pH 6.5, 37 °COpen record: β-ureidopropionase (HsβUP), N-carbamoyl-β-alanine
β-ureidopropionase (HsβUP)Homo sapiensN-carbamoyl-β-alanineβ-alanine (product, competitive inhibitor); apparent kcat/Km——6pH 6.5, 37 °COpen record: β-ureidopropionase (HsβUP), N-carbamoyl-β-alanine
β-ureidopropionase (HsβUP)Homo sapiensN-carbamoyl-β-alanine0.31——pH 7.4, 37 °COpen record: β-ureidopropionase (HsβUP), N-carbamoyl-β-alanine