CatLogenzyme kinetics catalog

Values CatLog read from this paper

Characterization of the Polyspecific Transferase of Murine Type I Fatty Acid Synthase (FAS) and Implications for Polyketide Synthase (PKS) Engineering

PMID 29328619doi:10.1021/acschembio.7b00718Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 17 records (47 values) from this paper: malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS) from Mus musculus.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 2 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.

EC 1.1.1.100, EC 1.3.1.39, EC 2.3.1.38, EC 2.3.1.39, EC 2.3.1.41, EC 2.3.1.85, EC 3.1.2.14, EC 4.2.1.59

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161GMus musculusacetoacetyl-CoA7.38.6 × 10⁻⁴8.5 × 10³Open
malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161GMus musculusacetyl-CoAacyl-CoA varied 0.1-100 μM; holo-ACP (60 μM)13.70.001638.4 × 10³Open
malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161GMus musculusacetyl-CoAholo-ACP (varied, extrapolated)99.20.0128.3 × 10³ calc.Open
malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161GMus musculusacyl carrier protein (holo, murine FAS ACP domain)—0.245—Open
malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161GMus musculusbutyryl-CoA10.80.001646.6 × 10³Open
malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161GMus musculuscrotonyl-CoA60.001364.4 × 10³Open
malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161GMus musculushydroxybutyryl-CoA6.10.001723.6 × 10³Open
malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161GMus musculusmalonyl-CoAacyl-CoA varied 0.1-100 μM; holo-ACP (60 μM)15.60.001281.22 × 10⁴Open
malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161GMus musculusmalonyl-CoAholo-ACP (varied, extrapolated)1190.00881.4 × 10⁴ calc.Open
malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161GMus musculusmethylbutyryl-CoA7.20.002063.5 × 10³Open
malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161GMus musculusmethylmalonyl-CoA46.2 × 10⁻⁴6.5 × 10³Open
malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161GMus musculusoctanoyl-CoA4.17.3 × 10⁻⁴5.6 × 10³Open
malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161GMus musculuspalmitoyl-CoA2.50.0048500Open
malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161GMus musculusphenylacetyl-CoA69.6 × 10⁻⁴6.2 × 10³Open
malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161GMus musculussuccinyl-CoA13.40.00216.4 × 10³Open
malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161G/R606AMus musculusacetyl-CoA130.0034 × 10³Open
malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161G/R606AMus musculusmalonyl-CoA50.018300Open