EC 1.3.1.39: enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
OxidoreductasesOpen in Browse
CatLog read 35 records for EC 1.3.1.39 from 2 papers, for 2 organisms. Names in these papers: saFabI (enoyl-acyl carrier protein reductase), malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 9 records for EC 1.3.1.39 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.3.1.39 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Mechanism and inhibition of saFabI, the enoyl reductase from Staphylococcus aureus | Staphylococcus aureus | 18 |
| Characterization of the Polyspecific Transferase of Murine Type I Fatty Acid Synthase (FAS) and Implications for Polyketide Synthase (PKS) Engineering | Mus musculus | 17 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161G | Mus musculus | acetoacetyl-CoA | 7.3 | 8.6 × 10⁻⁴ | 8.5 × 10³ | PMID 29328619 | Open record: malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS) variant C161G, acetoacetyl-CoA | |
| malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161G | Mus musculus | acetyl-CoAacyl-CoA varied 0.1-100 μM; holo-ACP (60 μM) | 13.7 | 0.00163 | 8.4 × 10³ | PMID 29328619 | Open record: malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS) variant C161G, acetyl-CoA | |
| malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161G | Mus musculus | acetyl-CoAholo-ACP (varied, extrapolated) | 99.2 | 0.012 | 8.3 × 10³ calc. | PMID 29328619 | Open record: malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS) variant C161G, acetyl-CoA | |
| malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161G | Mus musculus | acyl carrier protein (holo, murine FAS ACP domain) | — | 0.245 | — | PMID 29328619 | Open record: malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS) variant C161G, acyl carrier protein (holo, murine FAS ACP domain) | |
| malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161G | Mus musculus | butyryl-CoA | 10.8 | 0.00164 | 6.6 × 10³ | PMID 29328619 | Open record: malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS) variant C161G, butyryl-CoA | |
| malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161G | Mus musculus | crotonyl-CoA | 6 | 0.00136 | 4.4 × 10³ | PMID 29328619 | Open record: malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS) variant C161G, crotonyl-CoA | |
| malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161G | Mus musculus | hydroxybutyryl-CoA | 6.1 | 0.00172 | 3.6 × 10³ | PMID 29328619 | Open record: malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS) variant C161G, hydroxybutyryl-CoA | |
| malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161G | Mus musculus | malonyl-CoAacyl-CoA varied 0.1-100 μM; holo-ACP (60 μM) | 15.6 | 0.00128 | 1.22 × 10⁴ | PMID 29328619 | Open record: malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS) variant C161G, malonyl-CoA | |
| malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161G | Mus musculus | malonyl-CoAholo-ACP (varied, extrapolated) | 119 | 0.0088 | 1.4 × 10⁴ calc. | PMID 29328619 | Open record: malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS) variant C161G, malonyl-CoA | |
| malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161G | Mus musculus | methylbutyryl-CoA | 7.2 | 0.00206 | 3.5 × 10³ | PMID 29328619 | Open record: malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS) variant C161G, methylbutyryl-CoA | |
| malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161G | Mus musculus | methylmalonyl-CoA | 4 | 6.2 × 10⁻⁴ | 6.5 × 10³ | PMID 29328619 | Open record: malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS) variant C161G, methylmalonyl-CoA | |
| malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161G | Mus musculus | octanoyl-CoA | 4.1 | 7.3 × 10⁻⁴ | 5.6 × 10³ | PMID 29328619 | Open record: malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS) variant C161G, octanoyl-CoA | |
| malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161G | Mus musculus | palmitoyl-CoA | 2.5 | 0.0048 | 500 | PMID 29328619 | Open record: malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS) variant C161G, palmitoyl-CoA | |
| malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161G | Mus musculus | phenylacetyl-CoA | 6 | 9.6 × 10⁻⁴ | 6.2 × 10³ | PMID 29328619 | Open record: malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS) variant C161G, phenylacetyl-CoA | |
| malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161G | Mus musculus | succinyl-CoA | 13.4 | 0.0021 | 6.4 × 10³ | PMID 29328619 | Open record: malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS) variant C161G, succinyl-CoA | |
| malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161G/R606A | Mus musculus | acetyl-CoA | 13 | 0.003 | 4 × 10³ | PMID 29328619 | Open record: malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS) variant C161G/R606A, acetyl-CoA | |
| malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS)variant C161G/R606A | Mus musculus | malonyl-CoA | 5 | 0.018 | 300 | PMID 29328619 | Open record: malonyl/acetyltransferase (MAT) domain of fatty acid synthase (FAS) variant C161G/R606A, malonyl-CoA | |
| saFabI (enoyl-acyl carrier protein reductase) | Staphylococcus aureus | crotonyl (trans-2-butenoyl)-S. aureus acyl carrier protein | 0.193 | 0.0115 | 18 | pH 7.8, 25 °C | PMID 18335995 | Open record: saFabI (enoyl-acyl carrier protein reductase), crotonyl (trans-2-butenoyl)-S. aureus acyl carrier protein |
| saFabI (enoyl-acyl carrier protein reductase) | Staphylococcus aureus | NADH | — | — | 0.17 | pH 7.8, 25 °C | PMID 18335995 | Open record: saFabI (enoyl-acyl carrier protein reductase), NADH |
| saFabI (enoyl-acyl carrier protein reductase) | Staphylococcus aureus | NADPH | 2.17 | 0.0708 | 30.67 | pH 7.8, 25 °C | PMID 18335995 | Open record: saFabI (enoyl-acyl carrier protein reductase), NADPH |
| saFabI (enoyl-acyl carrier protein reductase) | Staphylococcus aureus | trans-2-dodecenoyl S. aureus acyl carrier protein (DDsaACP) | 2.17 | 0.0045 | 492 | pH 7.8, 25 °C | PMID 18335995 | Open record: saFabI (enoyl-acyl carrier protein reductase), trans-2-dodecenoyl S. aureus acyl carrier protein (DDsaACP) |
| saFabI (enoyl-acyl carrier protein reductase) | Staphylococcus aureus | trans-2-dodecenoyl-coenzyme A (printed "dodocenoyl-CoA") | 0.3 | 0.0241 | 13 | pH 7.8, 25 °C | PMID 18335995 | Open record: saFabI (enoyl-acyl carrier protein reductase), trans-2-dodecenoyl-coenzyme A (printed "dodocenoyl-CoA") |
| saFabI (enoyl-acyl carrier protein reductase) | Staphylococcus aureus | trans-2-dodecenoyl-N-acetylcysteamine | 0.507 | 0.0233 | 22 | pH 7.8, 25 °C | PMID 18335995 | Open record: saFabI (enoyl-acyl carrier protein reductase), trans-2-dodecenoyl-N-acetylcysteamine |
| saFabI (enoyl-acyl carrier protein reductase)variant A95V | Staphylococcus aureus | NADPH | — | 0.2694 | 0.12 | pH 7.8, 25 °C | PMID 18335995 | Open record: saFabI (enoyl-acyl carrier protein reductase) variant A95V, NADPH |
| saFabI (enoyl-acyl carrier protein reductase)variant A95V | Staphylococcus aureus | trans-2-dodecenoyl S. aureus acyl carrier protein (DDsaACP) | 0.307 | 0.0114 | 28 | pH 7.8, 25 °C | PMID 18335995 | Open record: saFabI (enoyl-acyl carrier protein reductase) variant A95V, trans-2-dodecenoyl S. aureus acyl carrier protein (DDsaACP) |
| saFabI (enoyl-acyl carrier protein reductase)variant F204S | Staphylococcus aureus | NADPH | — | 0.4296 | 2.8 | pH 7.8, 25 °C | PMID 18335995 | Open record: saFabI (enoyl-acyl carrier protein reductase) variant F204S, NADPH |
| saFabI (enoyl-acyl carrier protein reductase)variant F204S | Staphylococcus aureus | trans-2-dodecenoyl S. aureus acyl carrier protein (DDsaACP) | 2.622 | 0.0184 | 130 | pH 7.8, 25 °C | PMID 18335995 | Open record: saFabI (enoyl-acyl carrier protein reductase) variant F204S, trans-2-dodecenoyl S. aureus acyl carrier protein (DDsaACP) |
| saFabI (enoyl-acyl carrier protein reductase)variant I193S | Staphylococcus aureus | NADPH | — | — | 2.2 | pH 7.8, 25 °C | PMID 18335995 | Open record: saFabI (enoyl-acyl carrier protein reductase) variant I193S, NADPH |
| saFabI (enoyl-acyl carrier protein reductase)variant I193S | Staphylococcus aureus | trans-2-dodecenoyl S. aureus acyl carrier protein (DDsaACP) | — | — | 85 | pH 7.8, 25 °C | PMID 18335995 | Open record: saFabI (enoyl-acyl carrier protein reductase) variant I193S, trans-2-dodecenoyl S. aureus acyl carrier protein (DDsaACP) |
| saFabI (enoyl-acyl carrier protein reductase)variant K41N | Staphylococcus aureus | NADH | — | — | 1.2 | pH 7.8, 25 °C | PMID 18335995 | Open record: saFabI (enoyl-acyl carrier protein reductase) variant K41N, NADH |
| saFabI (enoyl-acyl carrier protein reductase)variant K41N | Staphylococcus aureus | NADPH | — | — | 0.6 | pH 7.8, 25 °C | PMID 18335995 | Open record: saFabI (enoyl-acyl carrier protein reductase) variant K41N, NADPH |
| saFabI (enoyl-acyl carrier protein reductase)variant R40Q | Staphylococcus aureus | NADH | — | — | 0.88 | pH 7.8, 25 °C | PMID 18335995 | Open record: saFabI (enoyl-acyl carrier protein reductase) variant R40Q, NADH |
| saFabI (enoyl-acyl carrier protein reductase)variant R40Q | Staphylococcus aureus | NADPH | — | — | 0.33 | pH 7.8, 25 °C | PMID 18335995 | Open record: saFabI (enoyl-acyl carrier protein reductase) variant R40Q, NADPH |
| saFabI (enoyl-acyl carrier protein reductase)variant R40Q/K41N | Staphylococcus aureus | NADH | — | — | 1.27 | pH 7.8, 25 °C | PMID 18335995 | Open record: saFabI (enoyl-acyl carrier protein reductase) variant R40Q/K41N, NADH |
| saFabI (enoyl-acyl carrier protein reductase)variant R40Q/K41N | Staphylococcus aureus | NADPH | — | — | 0.067 | pH 7.8, 25 °C | PMID 18335995 | Open record: saFabI (enoyl-acyl carrier protein reductase) variant R40Q/K41N, NADPH |