CatLogenzyme kinetics catalog

Values CatLog read from this paper

Catalytic properties of polymorphic human cytochrome P450 1B1 variants

PMID 10426814doi:10.1093/carcin/20.8.1607Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 20 records (40 values) from this paper: CYP1B1 Arg48,Ala119,Leu432,Asn453, CYP1B1 Arg48,Ala119,Val432,Asn453, CYP1B1 Arg48,Ser119,Leu432,Asn453 and 1 more from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 20 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.

EC 1.14.14.1, EC 4.2.1.152

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
CYP1B1 Arg48,Ala119,Leu432,Asn453Homo sapiens17beta-estradiolproduct measured: 4-hydroxyestradiol0.01520.00513.0 calc.pH 7.4Open
CYP1B1 Arg48,Ala119,Leu432,Asn453Homo sapiens17beta-estradiolproduct measured: 2-hydroxyestradiol0.0070.00691.0 calc.pH 7.4Open
CYP1B1 Arg48,Ala119,Leu432,Asn453Homo sapiensprogesterone6β-hydroxyprogesterone0.010.0250.40 calc.Open
CYP1B1 Arg48,Ala119,Leu432,Asn453Homo sapiensprogesterone16α-hydroxyprogesterone0.0380.0231.7 calc.Open
CYP1B1 Arg48,Ala119,Leu432,Asn453Homo sapienstestosterone0.0370.0172.2 calc.Open
CYP1B1 Arg48,Ala119,Val432,Asn453Homo sapiens17beta-estradiolproduct measured: 4-hydroxyestradiol0.02420.00534.6 calc.pH 7.4Open
CYP1B1 Arg48,Ala119,Val432,Asn453Homo sapiens17beta-estradiolproduct measured: 2-hydroxyestradiol0.00770.00571.3 calc.pH 7.4Open
CYP1B1 Arg48,Ala119,Val432,Asn453Homo sapiensprogesterone6β-hydroxyprogesterone0.0570.1670.34 calc.Open
CYP1B1 Arg48,Ala119,Val432,Asn453Homo sapiensprogesterone16α-hydroxyprogesterone0.1380.1540.900 calc.Open
CYP1B1 Arg48,Ala119,Val432,Asn453Homo sapienstestosterone0.0180.0480.38 calc.Open
CYP1B1 Arg48,Ser119,Leu432,Asn453Homo sapiens17beta-estradiolproduct measured: 4-hydroxyestradiol0.01920.00523.7 calc.pH 7.4Open
CYP1B1 Arg48,Ser119,Leu432,Asn453Homo sapiens17beta-estradiolproduct measured: 2-hydroxyestradiol0.01020.00841.2 calc.pH 7.4Open
CYP1B1 Arg48,Ser119,Leu432,Asn453Homo sapiensprogesterone6β-hydroxyprogesterone0.0230.0740.32 calc.Open
CYP1B1 Arg48,Ser119,Leu432,Asn453Homo sapiensprogesterone16α-hydroxyprogesterone0.0680.0461.5 calc.Open
CYP1B1 Arg48,Ser119,Leu432,Asn453Homo sapienstestosterone0.0420.0261.6 calc.Open
CYP1B1 Arg48,Ser119,Val432,Asn453Homo sapiens17beta-estradiolproduct measured: 4-hydroxyestradiol0.01830.00257.3 calc.pH 7.4Open
CYP1B1 Arg48,Ser119,Val432,Asn453Homo sapiens17beta-estradiolproduct measured: 2-hydroxyestradiol0.00559 × 10⁻⁴6.1 calc.pH 7.4Open
CYP1B1 Arg48,Ser119,Val432,Asn453Homo sapiensprogesterone6β-hydroxyprogesterone0.040.1090.37 calc.Open
CYP1B1 Arg48,Ser119,Val432,Asn453Homo sapiensprogesterone16α-hydroxyprogesterone0.090.0751.2 calc.Open
CYP1B1 Arg48,Ser119,Val432,Asn453Homo sapienstestosterone0.0250.0540.46 calc.Open