Values CatLog read from this paper
Selective inhibition of human 3β-hydroxysteroid dehydrogenase type 1 as a potential treatment for breast cancer
PMID 20736065doi:10.1016/j.jsbmb.2010.08.003Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 2 records (6 values) from this paper: 3beta-HSD1 (human 3beta-hydroxysteroid dehydrogenase/isomerase type 1), 3beta-HSD2 (human 3beta-hydroxysteroid dehydrogenase/isomerase type 2) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| 3beta-HSD1 (human 3beta-hydroxysteroid dehydrogenase/isomerase type 1)variant R195P | Homo sapiens | 5-androstene-3,17-dione | 1.07 | 0.0632 | 17 | pH 7.4, 27 °C | Open record: 3beta-HSD1 (human 3beta-hydroxysteroid dehydrogenase/isomerase type 1) variant R195P, 5-androstene-3,17-dione |
| 3beta-HSD2 (human 3beta-hydroxysteroid dehydrogenase/isomerase type 2)variant P195R | Homo sapiens | 5-androstene-3,17-dione | 1.458 | 0.1018 | 14.3 | pH 7.4, 27 °C | Open record: 3beta-HSD2 (human 3beta-hydroxysteroid dehydrogenase/isomerase type 2) variant P195R, 5-androstene-3,17-dione |