Values CatLog read from this paper

One substrate, five products: reactions catalyzed by the dihydroneopterin aldolase from Mycobacterium tuberculosis

PMID 23150985doi:10.1021/ja308350fOpen in Browse

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CatLog read 7 records (15 values) from this paper: dihydroneopterin aldolase (MtDHNA) from Mycobacterium tuberculosis.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 1.13.11.81, EC 4.1.2.25

Records read from this paper
EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsOpen record
dihydroneopterin aldolase (MtDHNA)Mycobacterium tuberculosis7,8-dihydromonapterin0.0061.54 × 10⁻⁴38pH 7, 25 °COpen record: dihydroneopterin aldolase (MtDHNA), 7,8-dihydromonapterin
dihydroneopterin aldolase (MtDHNA)Mycobacterium tuberculosis7,8-dihydroneopterin0.00541.65 × 10⁻⁴36pH 7, 25 °COpen record: dihydroneopterin aldolase (MtDHNA), 7,8-dihydroneopterin
dihydroneopterin aldolase (MtDHNA)Mycobacterium tuberculosis7,8-dihydroneopterinepimerase reaction (DHMP formation from DHNP); HEPES pH 7.00.00151.54 × 10⁻⁴9.8pH 7, 25 °COpen record: dihydroneopterin aldolase (MtDHNA), 7,8-dihydroneopterin
dihydroneopterin aldolase (MtDHNA)Mycobacterium tuberculosis7,8-dihydroneopterin0.00111.54 × 10⁻⁴7.3pH 7, 25 °COpen record: dihydroneopterin aldolase (MtDHNA), 7,8-dihydroneopterin
dihydroneopterin aldolase (MtDHNA)Mycobacterium tuberculosis7,8-dihydroneopterinDHNP consumption (all reactions); linear phase; 33 µM MtDHNA0.011——pH 7, 25 °COpen record: dihydroneopterin aldolase (MtDHNA), 7,8-dihydroneopterin
dihydroneopterin aldolase (MtDHNA)Mycobacterium tuberculosis7,8-dihydroneopterinHP formation (aldolase reaction); linear phase; 33 µM MtDHNA0.009——pH 7, 25 °COpen record: dihydroneopterin aldolase (MtDHNA), 7,8-dihydroneopterin
dihydroneopterin aldolase (MtDHNA)Mycobacterium tuberculosis7,8-dihydroneopterin1 mM DHNP; 3 µM MtDHNA; 100 mM HEPES pH 7.0; 50 mM NaCl0.0025——pH 7, 25 °COpen record: dihydroneopterin aldolase (MtDHNA), 7,8-dihydroneopterin