Values CatLog read from this paper

The molecular basis for acetylhistidine synthesis by HisAT/NAT16

PMID 40595645doi:10.1038/s41467-025-61145-xOpen in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 12 records (26 values) from this paper: histidine acetyltransferase HisAT (NAT16), histidine acetyltransferase HisAT (NAT16) F63S allele (Ser63, rs34985488-G), NAT16 (histidine acetyltransferase, HisAT) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 7 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.

EC 2.3.1.33

Records read from this paper
EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsOpen record
histidine acetyltransferase HisAT (NAT16)Homo sapiensacetyl coenzyme A8.910.008611.03 × 10³ calc.pH 7.5, 37 °COpen record: histidine acetyltransferase HisAT (NAT16), acetyl coenzyme A
histidine acetyltransferase HisAT (NAT16)Homo sapiensL-arginine0.7851.8530.426pH 7.5, 37 °COpen record: histidine acetyltransferase HisAT (NAT16), L-arginine
histidine acetyltransferase HisAT (NAT16)Homo sapiensL-histidine20 nM enzyme; mean of three independent series36.5——pH 7.5, 37 °COpen record: histidine acetyltransferase HisAT (NAT16), L-histidine
histidine acetyltransferase HisAT (NAT16)Homo sapiensL-histidine20 nM enzyme; L-His 0-4500 µM varied at fixed 50 µM Ac-CoA8.350.092190.7 calc.pH 7.5, 37 °COpen record: histidine acetyltransferase HisAT (NAT16), L-histidine
histidine acetyltransferase HisAT (NAT16)Homo sapiensL-histidineL-His 0-4500 µM varied at fixed 50 µM Ac-CoA; single assay230.138170 calc.pH 7.5, 37 °COpen record: histidine acetyltransferase HisAT (NAT16), L-histidine
histidine acetyltransferase HisAT (NAT16)Homo sapiensL-lysine0.2973.0070.105pH 7.5, 37 °COpen record: histidine acetyltransferase HisAT (NAT16), L-lysine
histidine acetyltransferase HisAT (NAT16)variant E108QHomo sapiensL-histidine34.20.257133 calc.pH 7.5, 37 °COpen record: histidine acetyltransferase HisAT (NAT16) variant E108Q, L-histidine
histidine acetyltransferase HisAT (NAT16)variant E122QHomo sapiensL-histidine9.890.23442.3 calc.pH 7.5, 37 °COpen record: histidine acetyltransferase HisAT (NAT16) variant E122Q, L-histidine
histidine acetyltransferase HisAT (NAT16) F63S allele (Ser63, rs34985488-G)Homo sapiensacetyl coenzyme A8.80.0154570 calc.pH 7.5, 37 °COpen record: histidine acetyltransferase HisAT (NAT16) F63S allele (Ser63, rs34985488-G), acetyl coenzyme A
histidine acetyltransferase HisAT (NAT16) F63S allele (Ser63, rs34985488-G)Homo sapiensL-histidine7.780.33223.4 calc.pH 7.5, 37 °COpen record: histidine acetyltransferase HisAT (NAT16) F63S allele (Ser63, rs34985488-G), L-histidine
NAT16 (histidine acetyltransferase, HisAT)Homo sapiensacetyl-CoA36.50.01981.9 × 10³pH 7.5, 37 °COpen record: NAT16 (histidine acetyltransferase, HisAT), acetyl-CoA
NAT16 (histidine acetyltransferase, HisAT)Homo sapiensL-histidine—0.215177pH 7.5, 37 °COpen record: NAT16 (histidine acetyltransferase, HisAT), L-histidine