Values CatLog read from this paper
Compared action of neutrophil proteinase 3 and elastase on model substrates. Favorable effect of S'-P' interactions on proteinase 3 catalysts
PMID 12538645doi:10.1074/jbc.m210074200Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 51 records (123 values) from this paper: neutrophil elastase (NE, human neutrophil elastase), proteinase 3 (Pr3, human neutrophil proteinase 3) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| neutrophil elastase (NE, human neutrophil elastase) | Homo sapiens | (7-methoxycoumarin-4-yl)acetyl-Ala-Ala-Ala-Ala-Lys-Gly-Asp-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2 | — | — | 5 | pH 7.4, 25 °C | Open record: neutrophil elastase (NE, human neutrophil elastase), (7-methoxycoumarin-4-yl)acetyl-Ala-Ala-Ala-Ala-Lys-Gly-Asp-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2 |
| neutrophil elastase (NE, human neutrophil elastase) | Homo sapiens | (7-methoxycoumarin-4-yl)acetyl-Ala-Ala-Pro-Leu-Lys-Gly-Asp-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2 | — | — | 1.2 | pH 7.4, 25 °C | Open record: neutrophil elastase (NE, human neutrophil elastase), (7-methoxycoumarin-4-yl)acetyl-Ala-Ala-Pro-Leu-Lys-Gly-Asp-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2 |
| neutrophil elastase (NE, human neutrophil elastase) | Homo sapiens | (7-methoxycoumarin-4-yl)acetyl-Ala-Ala-Pro-Val-Lys-Gly-Asp-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2 | — | — | 179 | pH 7.4, 25 °C | Open record: neutrophil elastase (NE, human neutrophil elastase), (7-methoxycoumarin-4-yl)acetyl-Ala-Ala-Pro-Val-Lys-Gly-Asp-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2 |
| neutrophil elastase (NE, human neutrophil elastase) | Homo sapiens | (7-methoxycoumarin-4-yl)acetyl-lysyl-(2-picolinoyl)-Tyr-Asp-Ala-Lys-Gly-Asp-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2 | — | — | 2.3 | pH 7.4, 25 °C | Open record: neutrophil elastase (NE, human neutrophil elastase), (7-methoxycoumarin-4-yl)acetyl-lysyl-(2-picolinoyl)-Tyr-Asp-Ala-Lys-Gly-Asp-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2 |
| neutrophil elastase (NE, human neutrophil elastase) | Homo sapiens | (7-methoxycoumarin-4-yl)acetyl-lysyl-(2-picolinoyl)-Tyr-Asp-Ile-Lys-Gly-Asp-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2 | — | — | 95 | pH 7.4, 25 °C | Open record: neutrophil elastase (NE, human neutrophil elastase), (7-methoxycoumarin-4-yl)acetyl-lysyl-(2-picolinoyl)-Tyr-Asp-Ile-Lys-Gly-Asp-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2 |
| neutrophil elastase (NE, human neutrophil elastase) | Homo sapiens | (7-methoxycoumarin-4-yl)acetyl-lysyl-(2-picolinoyl)-Tyr-Asp-Val-Lys-Gly-Asp-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2 | — | — | 88 | pH 7.4, 25 °C | Open record: neutrophil elastase (NE, human neutrophil elastase), (7-methoxycoumarin-4-yl)acetyl-lysyl-(2-picolinoyl)-Tyr-Asp-Val-Lys-Gly-Asp-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2 |
| neutrophil elastase (NE, human neutrophil elastase) | Homo sapiens | (7-methoxycoumarin-4-yl)acetyl-lysyl-(2-picolinoyl)-Val-Glu-Ala-Lys-Gly-Asp-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2 | — | — | 55 | pH 7.4, 25 °C | Open record: neutrophil elastase (NE, human neutrophil elastase), (7-methoxycoumarin-4-yl)acetyl-lysyl-(2-picolinoyl)-Val-Glu-Ala-Lys-Gly-Asp-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2 |
| neutrophil elastase (NE, human neutrophil elastase) | Homo sapiens | acetyl-Ala-Ala-Pro-Ala-p-nitroanilide | 4.7 | 1.7 | 2.8 | pH 7.4, 25 °C | Open record: neutrophil elastase (NE, human neutrophil elastase), acetyl-Ala-Ala-Pro-Ala-p-nitroanilide |
| neutrophil elastase (NE, human neutrophil elastase) | Homo sapiens | acetyl-Ala-Ala-Pro-Val-p-nitroanilide | 8.3 | 0.46 | 18 | pH 7.4, 25 °C | Open record: neutrophil elastase (NE, human neutrophil elastase), acetyl-Ala-Ala-Pro-Val-p-nitroanilide |
| neutrophil elastase (NE, human neutrophil elastase) | Homo sapiens | methoxysuccinyl-Ala-Ala-Pro-Val-p-nitroanilide | 10.6 | 0.1 | 107 | pH 7.4, 25 °C | Open record: neutrophil elastase (NE, human neutrophil elastase), methoxysuccinyl-Ala-Ala-Pro-Val-p-nitroanilide |
| neutrophil elastase (NE, human neutrophil elastase) | Homo sapiens | methoxysuccinyl-lysyl-(2-picolinoyl)-Ala-Pro-Val-p-nitroanilide | 1.5 | 0.03 | 54.3 | pH 7.4, 25 °C | Open record: neutrophil elastase (NE, human neutrophil elastase), methoxysuccinyl-lysyl-(2-picolinoyl)-Ala-Pro-Val-p-nitroanilide |
| neutrophil elastase (NE, human neutrophil elastase) | Homo sapiens | methoxysuccinyl-lysyl-(2-picolinoyl)-Tyr-Asp-Ala-p-nitroanilide | 0.9 | 0.13 | 6.8 | pH 7.4, 25 °C | Open record: neutrophil elastase (NE, human neutrophil elastase), methoxysuccinyl-lysyl-(2-picolinoyl)-Tyr-Asp-Ala-p-nitroanilide |
| neutrophil elastase (NE, human neutrophil elastase) | Homo sapiens | methoxysuccinyl-lysyl-(2-picolinoyl)-Tyr-Asp-Val-p-nitroanilide | 11 | 0.13 | 84.6 | pH 7.4, 25 °C | Open record: neutrophil elastase (NE, human neutrophil elastase), methoxysuccinyl-lysyl-(2-picolinoyl)-Tyr-Asp-Val-p-nitroanilide |
| neutrophil elastase (NE, human neutrophil elastase) | Homo sapiens | succinyl-Ala-Ala-Ala-Ala-p-nitroanilide | 0.45 | 0.13 | 3.46 | pH 7.4, 25 °C | Open record: neutrophil elastase (NE, human neutrophil elastase), succinyl-Ala-Ala-Ala-Ala-p-nitroanilide |
| neutrophil elastase (NE, human neutrophil elastase) | Homo sapiens | succinyl-Ala-Ala-Asp-Val-p-nitroanilide | 0.9 | 0.75 | 1.2 | pH 7.4, 25 °C | Open record: neutrophil elastase (NE, human neutrophil elastase), succinyl-Ala-Ala-Asp-Val-p-nitroanilide |
| neutrophil elastase (NE, human neutrophil elastase) | Homo sapiens | succinyl-Ala-Ala-Glu-Val-p-nitroanilide | 5.8 | 0.83 | 7 | pH 7.4, 25 °C | Open record: neutrophil elastase (NE, human neutrophil elastase), succinyl-Ala-Ala-Glu-Val-p-nitroanilide |
| neutrophil elastase (NE, human neutrophil elastase) | Homo sapiens | succinyl-Ala-Ala-Pro-Abu-p-nitroanilide | 9.1 | 0.57 | 15.8 | pH 7.4, 25 °C | Open record: neutrophil elastase (NE, human neutrophil elastase), succinyl-Ala-Ala-Pro-Abu-p-nitroanilide |
| neutrophil elastase (NE, human neutrophil elastase) | Homo sapiens | succinyl-Ala-Ala-Pro-Ala-p-nitroanilide | 10 | 1.35 | 7.4 | pH 7.4, 25 °C | Open record: neutrophil elastase (NE, human neutrophil elastase), succinyl-Ala-Ala-Pro-Ala-p-nitroanilide |
| neutrophil elastase (NE, human neutrophil elastase) | Homo sapiens | succinyl-Ala-Ala-Pro-Ile-p-nitroanilide | 0.41 | 0.46 | 0.86 | pH 7.4, 25 °C | Open record: neutrophil elastase (NE, human neutrophil elastase), succinyl-Ala-Ala-Pro-Ile-p-nitroanilide |
| neutrophil elastase (NE, human neutrophil elastase) | Homo sapiens | succinyl-Ala-Ala-Pro-Leu-p-nitroanilide | 0.3 | 1.6 | 0.19 | pH 7.4, 25 °C | Open record: neutrophil elastase (NE, human neutrophil elastase), succinyl-Ala-Ala-Pro-Leu-p-nitroanilide |
| neutrophil elastase (NE, human neutrophil elastase) | Homo sapiens | succinyl-Ala-Ala-Pro-Met-p-nitroanilide | 0.33 | 2.5 | 0.13 | pH 7.4, 25 °C | Open record: neutrophil elastase (NE, human neutrophil elastase), succinyl-Ala-Ala-Pro-Met-p-nitroanilide |
| neutrophil elastase (NE, human neutrophil elastase) | Homo sapiens | succinyl-Ala-Ala-Pro-Nle-p-nitroanilide | 0.3 | 2.5 | 0.12 | pH 7.4, 25 °C | Open record: neutrophil elastase (NE, human neutrophil elastase), succinyl-Ala-Ala-Pro-Nle-p-nitroanilide |
| neutrophil elastase (NE, human neutrophil elastase) | Homo sapiens | succinyl-Ala-Ala-Pro-Nva-p-nitroanilide | 6.9 | 1.2 | 5.7 | pH 7.4, 25 °C | Open record: neutrophil elastase (NE, human neutrophil elastase), succinyl-Ala-Ala-Pro-Nva-p-nitroanilide |
| neutrophil elastase (NE, human neutrophil elastase) | Homo sapiens | succinyl-Ala-Ala-Pro-Val-p-nitroanilide | 10.4 | 0.13 | 77.2 | pH 7.4, 25 °C | Open record: neutrophil elastase (NE, human neutrophil elastase), succinyl-Ala-Ala-Pro-Val-p-nitroanilide |
| neutrophil elastase (NE, human neutrophil elastase) | Homo sapiens | succinyl-Ala-Tyr-Leu-Val-p-nitroanilide | 2.7 | 0.09 | 28.9 | pH 7.4, 25 °C | Open record: neutrophil elastase (NE, human neutrophil elastase), succinyl-Ala-Tyr-Leu-Val-p-nitroanilide |
| neutrophil elastase (NE, human neutrophil elastase) | Homo sapiens | succinyl-Leu-Val-Glu-Ala-p-nitroanilide | 0.43 | 0.65 | 0.68 | pH 7.4, 25 °C | Open record: neutrophil elastase (NE, human neutrophil elastase), succinyl-Leu-Val-Glu-Ala-p-nitroanilide |
| neutrophil elastase (NE, human neutrophil elastase) | Homo sapiens | tert-butyloxycarbonyl-Ala-Ala-Pro-Ala-p-nitroanilide | 3.4 | 0.35 | 9.7 | pH 7.4, 25 °C | Open record: neutrophil elastase (NE, human neutrophil elastase), tert-butyloxycarbonyl-Ala-Ala-Pro-Ala-p-nitroanilide |
| proteinase 3 (Pr3, human neutrophil proteinase 3) | Homo sapiens | (7-methoxycoumarin-4-yl)acetyl-Ala-Ala-Ala-Ala-Lys-Gly-Asp-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2 | — | — | 2.6 | pH 7.4, 25 °C | Open record: proteinase 3 (Pr3, human neutrophil proteinase 3), (7-methoxycoumarin-4-yl)acetyl-Ala-Ala-Ala-Ala-Lys-Gly-Asp-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2 |
| proteinase 3 (Pr3, human neutrophil proteinase 3) | Homo sapiens | (7-methoxycoumarin-4-yl)acetyl-Ala-Ala-Pro-Leu-Lys-Gly-Asp-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2 | — | — | 0.115 | pH 7.4, 25 °C | Open record: proteinase 3 (Pr3, human neutrophil proteinase 3), (7-methoxycoumarin-4-yl)acetyl-Ala-Ala-Pro-Leu-Lys-Gly-Asp-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2 |
| proteinase 3 (Pr3, human neutrophil proteinase 3) | Homo sapiens | (7-methoxycoumarin-4-yl)acetyl-Ala-Ala-Pro-Val-Lys-Gly-Asp-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2 | — | — | 62 | pH 7.4, 25 °C | Open record: proteinase 3 (Pr3, human neutrophil proteinase 3), (7-methoxycoumarin-4-yl)acetyl-Ala-Ala-Pro-Val-Lys-Gly-Asp-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2 |
| proteinase 3 (Pr3, human neutrophil proteinase 3) | Homo sapiens | (7-methoxycoumarin-4-yl)acetyl-lysyl-(2-picolinoyl)-Tyr-Asp-Ala-Lys-Gly-Asp-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2 | — | — | 1.1 × 10³ | pH 7.4, 25 °C | Open record: proteinase 3 (Pr3, human neutrophil proteinase 3), (7-methoxycoumarin-4-yl)acetyl-lysyl-(2-picolinoyl)-Tyr-Asp-Ala-Lys-Gly-Asp-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2 |
| proteinase 3 (Pr3, human neutrophil proteinase 3) | Homo sapiens | (7-methoxycoumarin-4-yl)acetyl-lysyl-(2-picolinoyl)-Tyr-Asp-Ile-Lys-Gly-Asp-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2 | — | — | 910 | pH 7.4, 25 °C | Open record: proteinase 3 (Pr3, human neutrophil proteinase 3), (7-methoxycoumarin-4-yl)acetyl-lysyl-(2-picolinoyl)-Tyr-Asp-Ile-Lys-Gly-Asp-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2 |
| proteinase 3 (Pr3, human neutrophil proteinase 3) | Homo sapiens | (7-methoxycoumarin-4-yl)acetyl-lysyl-(2-picolinoyl)-Tyr-Asp-Val-Lys-Gly-Asp-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2 | — | — | 4.6 × 10³ | pH 7.4, 25 °C | Open record: proteinase 3 (Pr3, human neutrophil proteinase 3), (7-methoxycoumarin-4-yl)acetyl-lysyl-(2-picolinoyl)-Tyr-Asp-Val-Lys-Gly-Asp-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2 |
| proteinase 3 (Pr3, human neutrophil proteinase 3) | Homo sapiens | (7-methoxycoumarin-4-yl)acetyl-lysyl-(2-picolinoyl)-Val-Glu-Ala-Lys-Gly-Asp-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2 | — | — | 610 | pH 7.4, 25 °C | Open record: proteinase 3 (Pr3, human neutrophil proteinase 3), (7-methoxycoumarin-4-yl)acetyl-lysyl-(2-picolinoyl)-Val-Glu-Ala-Lys-Gly-Asp-N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl-NH2 |
| proteinase 3 (Pr3, human neutrophil proteinase 3) | Homo sapiens | acetyl-Ala-Ala-Pro-Ala-p-nitroanilide | 0.22 | 2.7 | 0.08 | pH 7.4, 25 °C | Open record: proteinase 3 (Pr3, human neutrophil proteinase 3), acetyl-Ala-Ala-Pro-Ala-p-nitroanilide |
| proteinase 3 (Pr3, human neutrophil proteinase 3) | Homo sapiens | acetyl-Ala-Ala-Pro-Val-p-nitroanilide | 1 | 2.8 | 0.36 | pH 7.4, 25 °C | Open record: proteinase 3 (Pr3, human neutrophil proteinase 3), acetyl-Ala-Ala-Pro-Val-p-nitroanilide |
| proteinase 3 (Pr3, human neutrophil proteinase 3) | Homo sapiens | methoxysuccinyl-Ala-Ala-Pro-Val-p-nitroanilide | 0.5 | 0.47 | 1.06 | pH 7.4, 25 °C | Open record: proteinase 3 (Pr3, human neutrophil proteinase 3), methoxysuccinyl-Ala-Ala-Pro-Val-p-nitroanilide |
| proteinase 3 (Pr3, human neutrophil proteinase 3) | Homo sapiens | methoxysuccinyl-lysyl-(2-picolinoyl)-Ala-Pro-Val-p-nitroanilide | 2.3 | 0.14 | 16.3 | pH 7.4, 25 °C | Open record: proteinase 3 (Pr3, human neutrophil proteinase 3), methoxysuccinyl-lysyl-(2-picolinoyl)-Ala-Pro-Val-p-nitroanilide |
| proteinase 3 (Pr3, human neutrophil proteinase 3) | Homo sapiens | methoxysuccinyl-lysyl-(2-picolinoyl)-Tyr-Asp-Ala-p-nitroanilide | 3.2 | 0.1 | 32 | pH 7.4, 25 °C | Open record: proteinase 3 (Pr3, human neutrophil proteinase 3), methoxysuccinyl-lysyl-(2-picolinoyl)-Tyr-Asp-Ala-p-nitroanilide |
| proteinase 3 (Pr3, human neutrophil proteinase 3) | Homo sapiens | methoxysuccinyl-lysyl-(2-picolinoyl)-Tyr-Asp-Val-p-nitroanilide | 2.4 | 0.013 | 184.6 | pH 7.4, 25 °C | Open record: proteinase 3 (Pr3, human neutrophil proteinase 3), methoxysuccinyl-lysyl-(2-picolinoyl)-Tyr-Asp-Val-p-nitroanilide |
| proteinase 3 (Pr3, human neutrophil proteinase 3) | Homo sapiens | succinyl-Ala-Ala-Ala-Ala-p-nitroanilide | — | — | 0.009 | pH 7.4, 25 °C | Open record: proteinase 3 (Pr3, human neutrophil proteinase 3), succinyl-Ala-Ala-Ala-Ala-p-nitroanilide |
| proteinase 3 (Pr3, human neutrophil proteinase 3) | Homo sapiens | succinyl-Ala-Ala-Asp-Val-p-nitroanilide | 1.4 | 0.62 | 2.3 | pH 7.4, 25 °C | Open record: proteinase 3 (Pr3, human neutrophil proteinase 3), succinyl-Ala-Ala-Asp-Val-p-nitroanilide |
| proteinase 3 (Pr3, human neutrophil proteinase 3) | Homo sapiens | succinyl-Ala-Ala-Glu-Val-p-nitroanilide | 1 | 0.97 | 1.02 | pH 7.4, 25 °C | Open record: proteinase 3 (Pr3, human neutrophil proteinase 3), succinyl-Ala-Ala-Glu-Val-p-nitroanilide |
| proteinase 3 (Pr3, human neutrophil proteinase 3) | Homo sapiens | succinyl-Ala-Ala-Pro-Abu-p-nitroanilide | 0.3 | 0.38 | 0.79 | pH 7.4, 25 °C | Open record: proteinase 3 (Pr3, human neutrophil proteinase 3), succinyl-Ala-Ala-Pro-Abu-p-nitroanilide |
| proteinase 3 (Pr3, human neutrophil proteinase 3) | Homo sapiens | succinyl-Ala-Ala-Pro-Ala-p-nitroanilide | 0.23 | 1.9 | 0.12 | pH 7.4, 25 °C | Open record: proteinase 3 (Pr3, human neutrophil proteinase 3), succinyl-Ala-Ala-Pro-Ala-p-nitroanilide |
| proteinase 3 (Pr3, human neutrophil proteinase 3) | Homo sapiens | succinyl-Ala-Ala-Pro-Ile-p-nitroanilide | 0.27 | 0.64 | 0.42 | pH 7.4, 25 °C | Open record: proteinase 3 (Pr3, human neutrophil proteinase 3), succinyl-Ala-Ala-Pro-Ile-p-nitroanilide |
| proteinase 3 (Pr3, human neutrophil proteinase 3) | Homo sapiens | succinyl-Ala-Ala-Pro-Nva-p-nitroanilide | 0.09 | 0.5 | 0.18 | pH 7.4, 25 °C | Open record: proteinase 3 (Pr3, human neutrophil proteinase 3), succinyl-Ala-Ala-Pro-Nva-p-nitroanilide |
| proteinase 3 (Pr3, human neutrophil proteinase 3) | Homo sapiens | succinyl-Ala-Ala-Pro-Val-p-nitroanilide | 0.2 | 0.6 | 0.36 | pH 7.4, 25 °C | Open record: proteinase 3 (Pr3, human neutrophil proteinase 3), succinyl-Ala-Ala-Pro-Val-p-nitroanilide |
| proteinase 3 (Pr3, human neutrophil proteinase 3) | Homo sapiens | succinyl-Ala-Tyr-Leu-Val-p-nitroanilide | 0.6 | 0.17 | 3.5 | pH 7.4, 25 °C | Open record: proteinase 3 (Pr3, human neutrophil proteinase 3), succinyl-Ala-Tyr-Leu-Val-p-nitroanilide |
| proteinase 3 (Pr3, human neutrophil proteinase 3) | Homo sapiens | succinyl-Leu-Val-Glu-Ala-p-nitroanilide | 0.37 | 0.9 | 0.4 | pH 7.4, 25 °C | Open record: proteinase 3 (Pr3, human neutrophil proteinase 3), succinyl-Leu-Val-Glu-Ala-p-nitroanilide |
| proteinase 3 (Pr3, human neutrophil proteinase 3) | Homo sapiens | tert-butyloxycarbonyl-Ala-Ala-Pro-Ala-p-nitroanilide | 0.5 | 2 | 0.25 | pH 7.4, 25 °C | Open record: proteinase 3 (Pr3, human neutrophil proteinase 3), tert-butyloxycarbonyl-Ala-Ala-Pro-Ala-p-nitroanilide |