Values CatLog read from this paper
Mechanism of substrate recognition by botulinum neurotoxin serotype A
PMID 17244603doi:10.1074/jbc.m611211200Open in Browse
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CatLog read 19 records (57 values) from this paper: botulinum neurotoxin serotype A light chain (BoNT/A LC/A) from Clostridium botulinum.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| botulinum neurotoxin serotype A light chain (BoNT/A LC/A) | Clostridium botulinum | SNAP25 | 60 | 0.016 | 3.7 × 10³ | pH 7.6, 37 °C | Open record: botulinum neurotoxin serotype A light chain (BoNT/A LC/A), SNAP25 |
| botulinum neurotoxin serotype A light chain (BoNT/A LC/A)variant C134A | Clostridium botulinum | SNAP25 | 11 | 0.061 | 190 | pH 7.6, 37 °C | Open record: botulinum neurotoxin serotype A light chain (BoNT/A LC/A) variant C134A, SNAP25 |
| botulinum neurotoxin serotype A light chain (BoNT/A LC/A)variant D370A | Clostridium botulinum | SNAP25 | 0.1 | 0.014 | 9.8 | pH 7.6, 37 °C | Open record: botulinum neurotoxin serotype A light chain (BoNT/A LC/A) variant D370A, SNAP25 |
| botulinum neurotoxin serotype A light chain (BoNT/A LC/A)variant D370R | Clostridium botulinum | SNAP25 | 0.02 | 0.011 | 1.4 | pH 7.6, 37 °C | Open record: botulinum neurotoxin serotype A light chain (BoNT/A LC/A) variant D370R, SNAP25 |
| botulinum neurotoxin serotype A light chain (BoNT/A LC/A)variant E257A | Clostridium botulinum | SNAP25 | 1.1 | 0.019 | 54 | pH 7.6, 37 °C | Open record: botulinum neurotoxin serotype A light chain (BoNT/A LC/A) variant E257A, SNAP25 |
| botulinum neurotoxin serotype A light chain (BoNT/A LC/A)variant E257K | Clostridium botulinum | SNAP25 | 0.1 | 0.027 | 3.7 | pH 7.6, 37 °C | Open record: botulinum neurotoxin serotype A light chain (BoNT/A LC/A) variant E257K, SNAP25 |
| botulinum neurotoxin serotype A light chain (BoNT/A LC/A)variant F163A | Clostridium botulinum | SNAP25 | 0.4 | 0.012 | 30 | pH 7.6, 37 °C | Open record: botulinum neurotoxin serotype A light chain (BoNT/A LC/A) variant F163A, SNAP25 |
| botulinum neurotoxin serotype A light chain (BoNT/A LC/A)variant F194A | Clostridium botulinum | SNAP25 | 0.2 | 0.009 | 22 | pH 7.6, 37 °C | Open record: botulinum neurotoxin serotype A light chain (BoNT/A LC/A) variant F194A, SNAP25 |
| botulinum neurotoxin serotype A light chain (BoNT/A LC/A)variant F194A/T220A | Clostridium botulinum | SNAP25 | 0.19 | 0.0092 | 20 | pH 7.6, 37 °C | Open record: botulinum neurotoxin serotype A light chain (BoNT/A LC/A) variant F194A/T220A, SNAP25 |
| botulinum neurotoxin serotype A light chain (BoNT/A LC/A)variant H269A | Clostridium botulinum | SNAP25 | 58 | 0.016 | 3.7 × 10³ | pH 7.6, 37 °C | Open record: botulinum neurotoxin serotype A light chain (BoNT/A LC/A) variant H269A, SNAP25 |
| botulinum neurotoxin serotype A light chain (BoNT/A LC/A)variant I115A | Clostridium botulinum | SNAP25 | 11 | 0.095 | 120 | pH 7.6, 37 °C | Open record: botulinum neurotoxin serotype A light chain (BoNT/A LC/A) variant I115A, SNAP25 |
| botulinum neurotoxin serotype A light chain (BoNT/A LC/A)variant K41A | Clostridium botulinum | SNAP25 | 12 | 0.098 | 120 | pH 7.6, 37 °C | Open record: botulinum neurotoxin serotype A light chain (BoNT/A LC/A) variant K41A, SNAP25 |
| botulinum neurotoxin serotype A light chain (BoNT/A LC/A)variant L175A | Clostridium botulinum | SNAP25 | 0.7 | 0.011 | 61 | pH 7.6, 37 °C | Open record: botulinum neurotoxin serotype A light chain (BoNT/A LC/A) variant L175A, SNAP25 |
| botulinum neurotoxin serotype A light chain (BoNT/A LC/A)variant L175A/R177A | Clostridium botulinum | SNAP25 | 0.8 | 0.0083 | 96 | pH 7.6, 37 °C | Open record: botulinum neurotoxin serotype A light chain (BoNT/A LC/A) variant L175A/R177A, SNAP25 |
| botulinum neurotoxin serotype A light chain (BoNT/A LC/A)variant Q162A | Clostridium botulinum | SNAP25 | 63 | 0.017 | 3.8 × 10³ | pH 7.6, 37 °C | Open record: botulinum neurotoxin serotype A light chain (BoNT/A LC/A) variant Q162A, SNAP25 |
| botulinum neurotoxin serotype A light chain (BoNT/A LC/A)variant R177A | Clostridium botulinum | SNAP25 | 1.1 | 0.012 | 91 | pH 7.6, 37 °C | Open record: botulinum neurotoxin serotype A light chain (BoNT/A LC/A) variant R177A, SNAP25 |
| botulinum neurotoxin serotype A light chain (BoNT/A LC/A)variant T176A | Clostridium botulinum | SNAP25 | 1.2 | 0.014 | 85 | pH 7.6, 37 °C | Open record: botulinum neurotoxin serotype A light chain (BoNT/A LC/A) variant T176A, SNAP25 |
| botulinum neurotoxin serotype A light chain (BoNT/A LC/A)variant T220A | Clostridium botulinum | SNAP25 | 0.3 | 0.02 | 12 | pH 7.6, 37 °C | Open record: botulinum neurotoxin serotype A light chain (BoNT/A LC/A) variant T220A, SNAP25 |
| botulinum neurotoxin serotype A light chain (BoNT/A LC/A)variant V129A | Clostridium botulinum | SNAP25 | 12 | 0.053 | 230 | pH 7.6, 37 °C | Open record: botulinum neurotoxin serotype A light chain (BoNT/A LC/A) variant V129A, SNAP25 |