CatLogenzyme kinetics catalog

Values CatLog read from this paper

Human Cytochrome P450 21A2, the Major Steroid 21-Hydroxylase: STRUCTURE OF THE ENZYME·PROGESTERONE SUBSTRATE COMPLEX AND RATE-LIMITING C-H BOND CLEAVAGE

PMID 25855791doi:10.1074/jbc.m115.646307Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 6 records (18 values) from this paper: cytochrome P450 21A2 (steroid 21-hydroxylase) from Homo sapiens, Bos taurus.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 1.14.14.16

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
cytochrome P450 21A2 (steroid 21-hydroxylase)variant C3B21RABos taurus17α-hydroxyprogesterone0.674.4 × 10⁻⁴1.57 × 10³pH 7.4, 37 °COpen
cytochrome P450 21A2 (steroid 21-hydroxylase)variant C3B21RABos taurusprogesterone0.785 × 10⁻⁴1.52 × 10³pH 7.4, 37 °COpen
cytochrome P450 21A2 (steroid 21-hydroxylase)Homo sapiens17α-hydroxyprogesterone40.00152.67 × 10³pH 7.4, 37 °COpen
cytochrome P450 21A2 (steroid 21-hydroxylase)Homo sapiens21,21,21-trideuterio-17α-hydroxyprogesterone0.50.001500pH 7.4, 37 °COpen
cytochrome P450 21A2 (steroid 21-hydroxylase)Homo sapiens21,21,21-trideuterioprogesterone0.433.7 × 10⁻⁴1.17 × 10³pH 7.4, 37 °COpen
cytochrome P450 21A2 (steroid 21-hydroxylase)Homo sapiensprogesterone2.82.1 × 10⁻⁴1.33 × 10⁴pH 7.4, 37 °COpen