Values CatLog read from this paper
NAD biosynthesis: identification of the tryptophan to quinolinate pathway in bacteria
PMID 14700627doi:10.1016/j.chembiol.2003.11.011Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 7 records (19 values) from this paper: 3-hydroxy-kynureninase (KYN), kynurenine-3-monooxygenase (KMO), 3-hydroxyanthranilate-3,4-dioxygenase (HAD) and 2 more from Ralstonia metallidurans, Cytophaga hutchinsonii.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
EC 1.13.11.6, EC 1.13.11.11, EC 1.14.13.9, EC 3.5.1.9, EC 3.7.1.3
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| 3-hydroxy-kynureninase (KYN) | Ralstonia metallidurans | L-3-hydroxykynurenine | 2.9 | 0.04 | 74 | pH 8 | Open record: 3-hydroxy-kynureninase (KYN), L-3-hydroxykynurenine |
| 3-hydroxy-kynureninase (KYN) | Ralstonia metallidurans | L-kynurenine | 4.52 | 0.07 | 64 | pH 8 | Open record: 3-hydroxy-kynureninase (KYN), L-kynurenine |
| 3-hydroxyanthranilate-3,4-dioxygenase (HAD) | Ralstonia metallidurans | 3-hydroxyanthranilate | 8.65 | 1.22 | 7.1 | pH 7.2 | Open record: 3-hydroxyanthranilate-3,4-dioxygenase (HAD), 3-hydroxyanthranilate |
| kynurenine-3-monooxygenase (KMO) | Cytophaga hutchinsonii | L-kynurenine | 2.15 | 0.076 | 28 | pH 8 | Open record: kynurenine-3-monooxygenase (KMO), L-kynurenine |
| kynurenine-3-monooxygenase (KMO) | Cytophaga hutchinsonii | NADPH | — | 0.089 | — | pH 8 | Open record: kynurenine-3-monooxygenase (KMO), NADPH |
| N-formylkynurenine formamidase (KFA)variant Stop82Tyr | Ralstonia metallidurans | N-formyl-L-kynurenine | 0.77 | 0.075 | 10.3 | pH 7.4, 37 °C | Open record: N-formylkynurenine formamidase (KFA) variant Stop82Tyr, N-formyl-L-kynurenine |
| tryptophan-2,3-dioxygenase (TDO) | Ralstonia metallidurans | L-tryptophan | 22.6 | 0.35 | 64 | pH 7 | Open record: tryptophan-2,3-dioxygenase (TDO), L-tryptophan |