Values CatLog read from this paper
Mode of binding of methyl acceptor substrates to the adrenaline-synthesizing enzyme phenylethanolamine N-methyltransferase: implications for catalysis
PMID 16363801doi:10.1021/bi051636bOpen in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 15 records (27 values) from this paper: phenylethanolamine N-methyltransferase (hPNMT) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 6 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| phenylethanolamine N-methyltransferase (hPNMT) | Homo sapiens | (±)-p-octopamine | 0.02 | 0.0055 | 3.7 | pH 8, 30 °C | Open record: phenylethanolamine N-methyltransferase (hPNMT), (±)-p-octopamine |
| phenylethanolamine N-methyltransferase (hPNMT) | Homo sapiens | (±)-phenylethanolamineTable 1 | 0.043 | 0.099 | 0.43 | pH 8, 30 °C | Open record: phenylethanolamine N-methyltransferase (hPNMT), (±)-phenylethanolamine |
| phenylethanolamine N-methyltransferase (hPNMT) | Homo sapiens | (±)-phenylethanolamineTable 5 | 0.047 | 0.099 | 0.47 calc. | pH 8, 30 °C | Open record: phenylethanolamine N-methyltransferase (hPNMT), (±)-phenylethanolamine |
| phenylethanolamine N-methyltransferase (hPNMT) | Homo sapiens | cis-(1R,2S)-2-amino-1-tetralol | 0.0048 | 0.0053 | 0.92 | pH 8, 30 °C | Open record: phenylethanolamine N-methyltransferase (hPNMT), cis-(1R,2S)-2-amino-1-tetralol |
| phenylethanolamine N-methyltransferase (hPNMT) | Homo sapiens | S-adenosyl-L-methionine | — | 0.0034 | — | pH 8, 30 °C | Open record: phenylethanolamine N-methyltransferase (hPNMT), S-adenosyl-L-methionine |
| phenylethanolamine N-methyltransferase (hPNMT)variant E185A | Homo sapiens | (±)-phenylethanolamine | 0.0028 | 0.102 | 0.028 calc. | pH 8, 30 °C | Open record: phenylethanolamine N-methyltransferase (hPNMT) variant E185A, (±)-phenylethanolamine |
| phenylethanolamine N-methyltransferase (hPNMT)variant E185A | Homo sapiens | S-adenosyl-L-methionine | — | 0.0017 | — | pH 8, 30 °C | Open record: phenylethanolamine N-methyltransferase (hPNMT) variant E185A, S-adenosyl-L-methionine |
| phenylethanolamine N-methyltransferase (hPNMT)variant E185D | Homo sapiens | (±)-phenylethanolamine | 0.0142 | 0.32 | 0.044 calc. | pH 8, 30 °C | Open record: phenylethanolamine N-methyltransferase (hPNMT) variant E185D, (±)-phenylethanolamine |
| phenylethanolamine N-methyltransferase (hPNMT)variant E185D | Homo sapiens | S-adenosyl-L-methionine | — | 0.014 | — | pH 8, 30 °C | Open record: phenylethanolamine N-methyltransferase (hPNMT) variant E185D, S-adenosyl-L-methionine |
| phenylethanolamine N-methyltransferase (hPNMT)variant E185Q | Homo sapiens | (±)-phenylethanolamine | 1.7 × 10⁻⁴ | 0.101 | 0.0017 calc. | pH 8, 30 °C | Open record: phenylethanolamine N-methyltransferase (hPNMT) variant E185Q, (±)-phenylethanolamine |
| phenylethanolamine N-methyltransferase (hPNMT)variant E185Q | Homo sapiens | S-adenosyl-L-methionine | — | 0.0013 | — | pH 8, 30 °C | Open record: phenylethanolamine N-methyltransferase (hPNMT) variant E185Q, S-adenosyl-L-methionine |
| phenylethanolamine N-methyltransferase (hPNMT)variant E219Q | Homo sapiens | (±)-phenylethanolamine | 0.048 | 0.179 | 0.27 calc. | pH 8, 30 °C | Open record: phenylethanolamine N-methyltransferase (hPNMT) variant E219Q, (±)-phenylethanolamine |
| phenylethanolamine N-methyltransferase (hPNMT)variant E219Q | Homo sapiens | S-adenosyl-L-methionine | — | 0.0067 | — | pH 8, 30 °C | Open record: phenylethanolamine N-methyltransferase (hPNMT) variant E219Q, S-adenosyl-L-methionine |
| phenylethanolamine N-methyltransferase (hPNMT)variant Y35F | Homo sapiens | (±)-phenylethanolamine | 0.0175 | 1.73 | 0.0101 calc. | pH 8, 30 °C | Open record: phenylethanolamine N-methyltransferase (hPNMT) variant Y35F, (±)-phenylethanolamine |
| phenylethanolamine N-methyltransferase (hPNMT)variant Y35F | Homo sapiens | S-adenosyl-L-methionine | — | 0.045 | — | pH 8, 30 °C | Open record: phenylethanolamine N-methyltransferase (hPNMT) variant Y35F, S-adenosyl-L-methionine |