Values CatLog read from this paper
Structural and functional analysis of SET8, a histone H4 Lys-20 methyltransferase
PMID 15933070doi:10.1101/gad.1318405Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 24 records (62 values) from this paper: hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase) | Homo sapiens | Ac-AKKHRKVLRD-NH2 | 0.0023 | 1.89 | 0.0012 | pH 7.5 | Open record: hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase), Ac-AKKHRKVLRD-NH2 |
| hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase) | Homo sapiens | Ac-AKQHRKVLRD-NH2 | 0.002 | 1.98 | 0.001 | pH 7.5 | Open record: hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase), Ac-AKQHRKVLRD-NH2 |
| hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase) | Homo sapiens | Ac-AKRERKVLRD-NH2 | — | — | 0.0015 | pH 7.5 | Open record: hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase), Ac-AKRERKVLRD-NH2 |
| hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase) | Homo sapiens | Ac-AKRFRKVLRD-NH2 | 0.0058 | 0.42 | 0.014 | pH 7.5 | Open record: hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase), Ac-AKRFRKVLRD-NH2 |
| hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase) | Homo sapiens | Ac-AKRHAKVLRD-NH2 | 0.0057 | 0.31 | 0.018 | pH 7.5 | Open record: hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase), Ac-AKRHAKVLRD-NH2 |
| hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase) | Homo sapiens | Ac-AKRHEKVLRD-NH2 | 0.004 | 1.99 | 0.002 | pH 7.5 | Open record: hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase), Ac-AKRHEKVLRD-NH2 |
| hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase) | Homo sapiens | Ac-AKRHKKVLRD-NH2 | 0.0065 | 0.36 | 0.018 | pH 7.5 | Open record: hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase), Ac-AKRHKKVLRD-NH2 |
| hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase) | Homo sapiens | Ac-AKRHQKVLRD-NH2 | 0.0047 | 0.53 | 0.0088 | pH 7.5 | Open record: hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase), Ac-AKRHQKVLRD-NH2 |
| hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase) | Homo sapiens | Ac-AKRHRKALRD-NH2 | 0.0018 | 0.39 | 0.0048 | pH 7.5 | Open record: hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase), Ac-AKRHRKALRD-NH2 |
| hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase) | Homo sapiens | Ac-AKRHRKFLRD-NH2 | 0.0058 | 0.16 | 0.035 | pH 7.5 | Open record: hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase), Ac-AKRHRKFLRD-NH2 |
| hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase) | Homo sapiens | Ac-AKRHRKVARD-NH2 | — | — | 3.3 × 10⁻⁴ | pH 7.5 | Open record: hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase), Ac-AKRHRKVARD-NH2 |
| hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase) | Homo sapiens | Ac-AKRHRKVFRD-NH2 | 0.006 | 0.11 | 0.053 | pH 7.5 | Open record: hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase), Ac-AKRHRKVFRD-NH2 |
| hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase) | Homo sapiens | Ac-AKRHRKVLAD-NH2 | 0.006 | 0.21 | 0.028 | pH 7.5 | Open record: hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase), Ac-AKRHRKVLAD-NH2 |
| hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase) | Homo sapiens | Ac-AKRHRKVLED-NH2 | 0.0043 | 0.29 | 0.0152 | pH 7.5 | Open record: hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase), Ac-AKRHRKVLED-NH2 |
| hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase) | Homo sapiens | Ac-AKRHRKVLLD-NH2 | 0.0067 | 0.022 | 0.37 | pH 7.5 | Open record: hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase), Ac-AKRHRKVLLD-NH2 |
| hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase) | Homo sapiens | Ac-AKRHRKVLRD-NH2 | 0.0072 | 0.4 | 0.018 | pH 7.5 | Open record: hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase), Ac-AKRHRKVLRD-NH2 |
| hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase)variant C270A | Homo sapiens | Ac-AKRHRKVLRD-NH2 | — | — | 0.0015 | pH 7.5 | Open record: hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase) variant C270A, Ac-AKRHRKVLRD-NH2 |
| hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase)variant E259A | Homo sapiens | Ac-AKRHRKVLRD-NH2 | — | — | 0.001 | pH 7.5 | Open record: hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase) variant E259A, Ac-AKRHRKVLRD-NH2 |
| hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase)variant E259Q | Homo sapiens | Ac-AKRHRKVLRD-NH2 | 0.002 | 0.87 | 0.0023 | pH 7.5 | Open record: hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase) variant E259Q, Ac-AKRHRKVLRD-NH2 |
| hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase)variant H347A | Homo sapiens | Ac-AKRHRKVLRD-NH2 | 0.0033 | 1.02 | 0.0033 | pH 7.5 | Open record: hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase) variant H347A, Ac-AKRHRKVLRD-NH2 |
| hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase)variant H347E | Homo sapiens | Ac-AKRHRKVLRD-NH2 | 0.0013 | 0.47 | 0.0028 | pH 7.5 | Open record: hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase) variant H347E, Ac-AKRHRKVLRD-NH2 |
| hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase)variant H347F | Homo sapiens | Ac-AKRHRKVLRD-NH2 | 0.0035 | 0.0074 | 0.47 | pH 7.5 | Open record: hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase) variant H347F, Ac-AKRHRKVLRD-NH2 |
| hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase)variant Y334A | Homo sapiens | Ac-AKRHRKVLRD-NH2 | — | — | 8.3 × 10⁻⁵ | pH 7.5 | Open record: hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase) variant Y334A, Ac-AKRHRKVLRD-NH2 |
| hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase)variant Y334F | Homo sapiens | Ac-AKRHRKVLRD-NH2 | 0.0075 | 0.52 | 0.015 | pH 7.5 | Open record: hSET8 (SET8/PR-SET7, histone H4 Lys-20 methyltransferase) variant Y334F, Ac-AKRHRKVLRD-NH2 |