Values CatLog read from this paper
Gut Bacterial 20-Hydroxysteroid Dehydrogenases Modify Endogenous Glucocorticoids and Corticosteroid Drugs
PMID 42338389doi:10.1021/acs.biochem.5c00661Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 15 records (43 values) from this paper: AdDesE (20β-hydroxysteroid dehydrogenase), BaDesE (20β-hydroxysteroid dehydrogenase), CsDesC (20α-hydroxysteroid dehydrogenase) from Agathobaculum desmolans, Bifidobacterium adolescentis, Clostridium scindens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| AdDesE (20β-hydroxysteroid dehydrogenase) | Agathobaculum desmolans | Cortisol | 2.1 | 0.065 | 33 | pH 5 | Open record: AdDesE (20β-hydroxysteroid dehydrogenase), Cortisol |
| AdDesE (20β-hydroxysteroid dehydrogenase) | Agathobaculum desmolans | Cortisol | 0.065 | 0.011 | 6 | pH 7.2 | Open record: AdDesE (20β-hydroxysteroid dehydrogenase), Cortisol |
| AdDesE (20β-hydroxysteroid dehydrogenase) | Agathobaculum desmolans | Prednisolone | — | — | 0.089 | pH 5 | Open record: AdDesE (20β-hydroxysteroid dehydrogenase), Prednisolone |
| AdDesE (20β-hydroxysteroid dehydrogenase) | Agathobaculum desmolans | Prednisolone | 0.052 | 0.011 | 4.8 | pH 7.2 | Open record: AdDesE (20β-hydroxysteroid dehydrogenase), Prednisolone |
| AdDesE (20β-hydroxysteroid dehydrogenase) | Agathobaculum desmolans | Prednisone | 0.129 | 0.012 | 11 | pH 5 | Open record: AdDesE (20β-hydroxysteroid dehydrogenase), Prednisone |
| AdDesE (20β-hydroxysteroid dehydrogenase) | Agathobaculum desmolans | Prednisone | 0.116 | 0.0025 | 50 | pH 7.2 | Open record: AdDesE (20β-hydroxysteroid dehydrogenase), Prednisone |
| AdDesE (20β-hydroxysteroid dehydrogenase) | Agathobaculum desmolans | Triamcinolone | 0.063 | 0.16 | 0.39 | pH 7.2 | Open record: AdDesE (20β-hydroxysteroid dehydrogenase), Triamcinolone |
| BaDesE (20β-hydroxysteroid dehydrogenase) | Bifidobacterium adolescentis | Cortisol | 1.8 | 0.013 | 140 | pH 5 | Open record: BaDesE (20β-hydroxysteroid dehydrogenase), Cortisol |
| BaDesE (20β-hydroxysteroid dehydrogenase) | Bifidobacterium adolescentis | Cortisol | 3.6 | 0.0011 | 3.2 × 10³ | pH 7.2 | Open record: BaDesE (20β-hydroxysteroid dehydrogenase), Cortisol |
| BaDesE (20β-hydroxysteroid dehydrogenase) | Bifidobacterium adolescentis | Prednisolone | 2.12 | 0.016 | 130 | pH 5 | Open record: BaDesE (20β-hydroxysteroid dehydrogenase), Prednisolone |
| BaDesE (20β-hydroxysteroid dehydrogenase) | Bifidobacterium adolescentis | Prednisolone | 9 | 0.004 | 2 × 10³ | pH 7.2 | Open record: BaDesE (20β-hydroxysteroid dehydrogenase), Prednisolone |
| BaDesE (20β-hydroxysteroid dehydrogenase) | Bifidobacterium adolescentis | Prednisone | 2.3 | 0.019 | 120 | pH 5 | Open record: BaDesE (20β-hydroxysteroid dehydrogenase), Prednisone |
| BaDesE (20β-hydroxysteroid dehydrogenase) | Bifidobacterium adolescentis | Prednisone | 10 | 0.007 | 1.4 × 10³ | pH 7.2 | Open record: BaDesE (20β-hydroxysteroid dehydrogenase), Prednisone |
| BaDesE (20β-hydroxysteroid dehydrogenase) | Bifidobacterium adolescentis | Triamcinolone | 0.58 | 0.65 | 0.89 | pH 7.2 | Open record: BaDesE (20β-hydroxysteroid dehydrogenase), Triamcinolone |
| CsDesC (20α-hydroxysteroid dehydrogenase) | Clostridium scindens | Prednisolone | 0.28 | 0.16 | 1.8 | pH 7.2 | Open record: CsDesC (20α-hydroxysteroid dehydrogenase), Prednisolone |