CatLogenzyme kinetics catalog

Values CatLog read from this paper

Effects of mutations of active site residues and amino acids interacting with the Omega loop on substrate activation of butyrylcholinesterase

PMID 11341926doi:10.1016/s0167-4838(00)00217-xOpen in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 27 records (73 values) from this paper: butyrylcholinesterase (BuChE) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.1.1.8

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
butyrylcholinesterase (BuChE)variant A328FHomo sapiensbutyrylthiocholinebuffer5330.0173.3 × 10⁴pH 7, 25 °COpen
butyrylcholinesterase (BuChE)variant A328FHomo sapiensbutyrylthiocholinebuffer with 24% (w/v) fructose4500.0133.7 × 10⁴pH 7, 25 °COpen
butyrylcholinesterase (BuChE)variant A328GHomo sapiensbutyrylthiocholinebuffer3330.0281.18 × 10⁴pH 7, 25 °COpen
butyrylcholinesterase (BuChE)variant A328GHomo sapiensbutyrylthiocholinebuffer with 24% (w/v) fructose—0.027—pH 7, 25 °COpen
butyrylcholinesterase (BuChE)variant A328YHomo sapiensbutyrylthiocholinebuffer6670.0116 × 10⁴pH 7, 25 °COpen
butyrylcholinesterase (BuChE)variant A328YHomo sapiensbutyrylthiocholinebuffer with 24% (w/v) fructose8330.0117 × 10⁴pH 7, 25 °COpen
butyrylcholinesterase (BuChE)variant E197DHomo sapiensbutyrylthiocholinebuffer66.70.1670pH 7, 25 °COpen
butyrylcholinesterase (BuChE)variant E197DHomo sapiensbutyrylthiocholinebuffer with 24% (w/v) fructose66.70.1670pH 7, 25 °COpen
butyrylcholinesterase (BuChE)variant E197GHomo sapiensbutyrylthiocholinebuffer—0.2—pH 7, 25 °COpen
butyrylcholinesterase (BuChE)variant E197GHomo sapiensbutyrylthiocholinebuffer with 24% (w/v) fructose—0.17—pH 7, 25 °COpen
butyrylcholinesterase (BuChE)variant E197QHomo sapiensbutyrylthiocholinebuffer1500.11.5 × 10³pH 7, 25 °COpen
butyrylcholinesterase (BuChE)variant E197QHomo sapiensbutyrylthiocholinebuffer with 24% (w/v) fructose2000.111.8 × 10³pH 7, 25 °COpen
butyrylcholinesterase (BuChE)variant K339MHomo sapiensbutyrylthiocholinebuffer2500.064.7 × 10³pH 7, 25 °COpen
butyrylcholinesterase (BuChE)variant K339MHomo sapiensbutyrylthiocholinebuffer with 24% (w/v) fructose3330.084.2 × 10³pH 7, 25 °COpen
butyrylcholinesterase (BuChE)variant K339MHomo sapienso-nitrophenyl butyrate2500.161.57 × 10³pH 7, 25 °COpen
butyrylcholinesterase (BuChE)variant K339MHomo sapienssuccinyldithiocholine3.30.019170pH 7, 25 °COpen
butyrylcholinesterase (BuChE)variant N83AHomo sapiensbutyrylthiocholinebuffer6170.051.23 × 10⁴pH 7, 25 °COpen
butyrylcholinesterase (BuChE)variant N83AHomo sapiensbutyrylthiocholinebuffer with 24% (w/v) fructose6670.061.1 × 10⁴pH 7, 25 °COpen
butyrylcholinesterase (BuChE)variant N83QHomo sapiensbutyrylthiocholinebuffer7670.061.28 × 10⁴pH 7, 25 °COpen
butyrylcholinesterase (BuChE)variant N83QHomo sapiensbutyrylthiocholinebuffer with 24% (w/v) fructose9170.061.52 × 10⁴pH 7, 25 °COpen
butyrylcholinesterase (BuChE)variant W430AHomo sapiensbutyrylthiocholinebuffer83.3613pH 7, 25 °COpen
butyrylcholinesterase (BuChE)variant W430AHomo sapiensbutyrylthiocholinebuffer with 24% (w/v) fructose100425pH 7, 25 °COpen
butyrylcholinesterase (BuChE)variant W430AHomo sapienso-nitrophenyl butyrate3331.9170pH 7, 25 °COpen
butyrylcholinesterase (BuChE)variant W430AHomo sapienssuccinyldithiocholine3.3110.33pH 7, 25 °COpen
butyrylcholinesterase (BuChE)variant W82AHomo sapiensbutyrylthiocholine0.1 M potassium phosphate buffer20.45pH 7, 25 °COpen
butyrylcholinesterase (BuChE)variant W82AHomo sapiensbutyrylthiocholine0.1 M potassium phosphate buffer with 24% (w/v) fructose6.71.74pH 7, 25 °COpen
butyrylcholinesterase (BuChE)variant W82AHomo sapiensbutyrylthiocholine0.1 M potassium phosphate buffer; the remaining 80% assayed—0.9—pH 7, 25 °COpen