Values CatLog read from this paper
Inhibition of the Escherichia coli pyruvate dehydrogenase complex E1 subunit and its tyrosine 177 variants by thiamin 2-thiazolone and thiamin 2-thiothiazolone diphosphates. Evidence for reversible…
PMID 11583990doi:10.1074/jbc.m104116200Open in Browse
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CatLog read 6 records (9 values) from this paper: pyruvate dehydrogenase (E1 subunit of the pyruvate dehydrogenase multienzyme complex) from Escherichia coli.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| pyruvate dehydrogenase (E1 subunit of the pyruvate dehydrogenase multienzyme complex) | Escherichia coli | pyruvateTable I | 28.89 | — | — | pH 8, 30 °C | Open record: pyruvate dehydrogenase (E1 subunit of the pyruvate dehydrogenase multienzyme complex), pyruvate |
| pyruvate dehydrogenase (E1 subunit of the pyruvate dehydrogenase multienzyme complex) | Escherichia coli | pyruvateTable II | — | 0.515 | 56 | pH 8, 30 °C | Open record: pyruvate dehydrogenase (E1 subunit of the pyruvate dehydrogenase multienzyme complex), pyruvate |
| pyruvate dehydrogenase (E1 subunit of the pyruvate dehydrogenase multienzyme complex)variant Y177A | Escherichia coli | pyruvateTable I | 3.31 | — | — | pH 8, 30 °C | Open record: pyruvate dehydrogenase (E1 subunit of the pyruvate dehydrogenase multienzyme complex) variant Y177A, pyruvate |
| pyruvate dehydrogenase (E1 subunit of the pyruvate dehydrogenase multienzyme complex)variant Y177A | Escherichia coli | pyruvateTable II | — | 0.28 | 12 | pH 8, 30 °C | Open record: pyruvate dehydrogenase (E1 subunit of the pyruvate dehydrogenase multienzyme complex) variant Y177A, pyruvate |
| pyruvate dehydrogenase (E1 subunit of the pyruvate dehydrogenase multienzyme complex)variant Y177A | Escherichia coli | thiamin diphosphate | — | 0.00665 | 498 | pH 8, 30 °C | Open record: pyruvate dehydrogenase (E1 subunit of the pyruvate dehydrogenase multienzyme complex) variant Y177A, thiamin diphosphate |
| pyruvate dehydrogenase (E1 subunit of the pyruvate dehydrogenase multienzyme complex)variant Y177F | Escherichia coli | pyruvate | — | 0.531 | — | pH 8, 30 °C | Open record: pyruvate dehydrogenase (E1 subunit of the pyruvate dehydrogenase multienzyme complex) variant Y177F, pyruvate |