Values CatLog read from this paper

Mutagenesis of residue 157 in the active site of human glyoxalase I

PMID 9359858doi:10.1042/bj3280231Open in Browse

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CatLog read 7 records (15 values) from this paper: glyoxalase I from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 4.4.1.5

Records read from this paper
EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsOpen record
glyoxalase IHomo sapienshemithioacetal of GSH and methylglyoxal1.5 × 10³0.0662.3 × 10⁴pH 7, 30 °COpen record: glyoxalase I, hemithioacetal of GSH and methylglyoxal
glyoxalase Ivariant M157AHomo sapienshemithioacetal of GSH and methylglyoxal2600.0744 × 10³pH 7, 30 °COpen record: glyoxalase I variant M157A, hemithioacetal of GSH and methylglyoxal
glyoxalase Ivariant M157AHomo sapienshemithioacetal of GSH and phenylglyoxal——1 × 10⁴pH 7, 30 °COpen record: glyoxalase I variant M157A, hemithioacetal of GSH and phenylglyoxal
glyoxalase Ivariant M157HHomo sapienshemithioacetal of GSH and methylglyoxal3000.0893 × 10³pH 7, 30 °COpen record: glyoxalase I variant M157H, hemithioacetal of GSH and methylglyoxal
glyoxalase Ivariant M157HHomo sapienshemithioacetal of GSH and phenylglyoxal——1 × 10⁴pH 7, 30 °COpen record: glyoxalase I variant M157H, hemithioacetal of GSH and phenylglyoxal
glyoxalase Ivariant M157QHomo sapienshemithioacetal of GSH and methylglyoxal1.65 × 10³0.1621 × 10⁴pH 7, 30 °COpen record: glyoxalase I variant M157Q, hemithioacetal of GSH and methylglyoxal
glyoxalase Ivariant M157QHomo sapienshemithioacetal of GSH and phenylglyoxal——4.4 × 10⁴pH 7, 30 °COpen record: glyoxalase I variant M157Q, hemithioacetal of GSH and phenylglyoxal