Values CatLog read from this paper
New insights from the structure-function analysis of the catalytic region of human platelet phosphodiesterase 3A: a role for the unique 44-amino acid insert
PMID 16873361doi:10.1074/jbc.m606558200Open in Browse
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CatLog read 14 records (42 values) from this paper: phosphodiesterase 3A (PDE3A), catalytic region from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| phosphodiesterase 3A (PDE3A), catalytic region | Homo sapiens | adenosine 3',5'-cyclic monophosphate | 1.78 | 2.3 × 10⁻⁴ | 7.78 × 10³ | pH 7.8, 30 °C | Open record: phosphodiesterase 3A (PDE3A), catalytic region, adenosine 3',5'-cyclic monophosphate |
| phosphodiesterase 3A (PDE3A), catalytic regionvariant C816S | Homo sapiens | adenosine 3',5'-cyclic monophosphate | 0.085 | 3.4 × 10⁻⁴ | 250 | pH 7.8, 30 °C | Open record: phosphodiesterase 3A (PDE3A), catalytic region variant C816S, adenosine 3',5'-cyclic monophosphate |
| phosphodiesterase 3A (PDE3A), catalytic regionvariant D811A | Homo sapiens | adenosine 3',5'-cyclic monophosphate | 1.36 | 1.7 × 10⁻⁴ | 8.02 × 10³ | pH 7.8, 30 °C | Open record: phosphodiesterase 3A (PDE3A), catalytic region variant D811A, adenosine 3',5'-cyclic monophosphate |
| phosphodiesterase 3A (PDE3A), catalytic regionvariant D812A | Homo sapiens | adenosine 3',5'-cyclic monophosphate | 0.5 | 2 × 10⁻⁴ | 2.5 × 10³ | pH 7.8, 30 °C | Open record: phosphodiesterase 3A (PDE3A), catalytic region variant D812A, adenosine 3',5'-cyclic monophosphate |
| phosphodiesterase 3A (PDE3A), catalytic regionvariant G815A | Homo sapiens | adenosine 3',5'-cyclic monophosphate | 0.867 | 2.6 × 10⁻⁴ | 3.4 × 10³ | pH 7.8, 30 °C | Open record: phosphodiesterase 3A (PDE3A), catalytic region variant G815A, adenosine 3',5'-cyclic monophosphate |
| phosphodiesterase 3A (PDE3A), catalytic regionvariant H782A | Homo sapiens | adenosine 3',5'-cyclic monophosphate | 0.223 | 4.5 × 10⁻⁴ | 500 | pH 7.8, 30 °C | Open record: phosphodiesterase 3A (PDE3A), catalytic region variant H782A, adenosine 3',5'-cyclic monophosphate |
| phosphodiesterase 3A (PDE3A), catalytic regionvariant H796A | Homo sapiens | adenosine 3',5'-cyclic monophosphate | 1.656 | 2 × 10⁻⁴ | 8.28 × 10³ | pH 7.8, 30 °C | Open record: phosphodiesterase 3A (PDE3A), catalytic region variant H796A, adenosine 3',5'-cyclic monophosphate |
| phosphodiesterase 3A (PDE3A), catalytic regionvariant H798A | Homo sapiens | adenosine 3',5'-cyclic monophosphate | 1.013 | 2.5 × 10⁻⁴ | 4.14 × 10³ | pH 7.8, 30 °C | Open record: phosphodiesterase 3A (PDE3A), catalytic region variant H798A, adenosine 3',5'-cyclic monophosphate |
| phosphodiesterase 3A (PDE3A), catalytic regionvariant K805A | Homo sapiens | adenosine 3',5'-cyclic monophosphate | 0.763 | 2.7 × 10⁻⁴ | 2.88 × 10³ | pH 7.8, 30 °C | Open record: phosphodiesterase 3A (PDE3A), catalytic region variant K805A, adenosine 3',5'-cyclic monophosphate |
| phosphodiesterase 3A (PDE3A), catalytic regionvariant S804A | Homo sapiens | adenosine 3',5'-cyclic monophosphate | 0.69 | 2.8 × 10⁻⁴ | 2.51 × 10³ | pH 7.8, 30 °C | Open record: phosphodiesterase 3A (PDE3A), catalytic region variant S804A, adenosine 3',5'-cyclic monophosphate |
| phosphodiesterase 3A (PDE3A), catalytic regionvariant T810A | Homo sapiens | adenosine 3',5'-cyclic monophosphate | 0.369 | 5.3 × 10⁻⁴ | 690 | pH 7.8, 30 °C | Open record: phosphodiesterase 3A (PDE3A), catalytic region variant T810A, adenosine 3',5'-cyclic monophosphate |
| phosphodiesterase 3A (PDE3A), catalytic regionvariant Y807A | Homo sapiens | adenosine 3',5'-cyclic monophosphate | 0.84 | 0.00679 | 120 | pH 7.8, 30 °C | Open record: phosphodiesterase 3A (PDE3A), catalytic region variant Y807A, adenosine 3',5'-cyclic monophosphate |
| phosphodiesterase 3A (PDE3A), catalytic regionvariant Y807C | Homo sapiens | adenosine 3',5'-cyclic monophosphate | 1.05 | 1.6 × 10⁻⁴ | 6.58 × 10³ | pH 7.8, 30 °C | Open record: phosphodiesterase 3A (PDE3A), catalytic region variant Y807C, adenosine 3',5'-cyclic monophosphate |
| phosphodiesterase 3A (PDE3A), catalytic regionvariant Y814A | Homo sapiens | adenosine 3',5'-cyclic monophosphate | 0.231 | 6.5 × 10⁻⁴ | 360 | pH 7.8, 30 °C | Open record: phosphodiesterase 3A (PDE3A), catalytic region variant Y814A, adenosine 3',5'-cyclic monophosphate |