Values CatLog read from this paper
Analysis of flavin oxidation and electron-transfer inhibition in Plasmodium falciparum dihydroorotate dehydrogenase
PMID 18225919doi:10.1021/bi702218cOpen in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 37 records (64 values) from this paper: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) from Plasmodium falciparum.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 27 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) | Plasmodium falciparum | decylubiquinone | 12 | 0.013 | 920 calc. | pH 8, 25 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase), decylubiquinone |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) | Plasmodium falciparum | dihydroorotate | 0.42 | — | — | pH 8, 25 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase), dihydroorotate |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) | Plasmodium falciparum | ubiquinone-1 | 7.8 | 0.011 | 710 calc. | pH 8, 25 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase), ubiquinone-1 |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) | Plasmodium falciparum | ubiquinone-1 | 6.3 | 0.016 | 390 calc. | pH 8, 4 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase), ubiquinone-1 |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant F188A | Plasmodium falciparum | decylubiquinone | 4.3 | 0.02 | 220 calc. | pH 8, 25 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant F188A, decylubiquinone |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant F188A | Plasmodium falciparum | dihydroorotate | 0.53 | — | — | pH 8, 25 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant F188A, dihydroorotate |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant F188A | Plasmodium falciparum | ubiquinone-1 | 2.6 | 0.015 | 170 calc. | pH 8, 25 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant F188A, ubiquinone-1 |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant F188A | Plasmodium falciparum | ubiquinone-1 | 2.8 | 0.026 | 110 calc. | pH 8, 4 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant F188A, ubiquinone-1 |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant F227A | Plasmodium falciparum | decylubiquinone | 3.5 | 0.02 | 180 calc. | pH 8, 25 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant F227A, decylubiquinone |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant F227A | Plasmodium falciparum | dihydroorotate | 0.43 | — | — | pH 8, 25 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant F227A, dihydroorotate |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant F227A | Plasmodium falciparum | ubiquinone-1 | 2.6 | 0.016 | 160 calc. | pH 8, 25 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant F227A, ubiquinone-1 |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant F227A | Plasmodium falciparum | ubiquinone-1 | 1.7 | 0.018 | 94 calc. | pH 8, 4 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant F227A, ubiquinone-1 |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant H185A | Plasmodium falciparum | decylubiquinone | 7.9 | 0.034 | 230 calc. | pH 8, 25 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant H185A, decylubiquinone |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant H185A | Plasmodium falciparum | dihydroorotate | 0.57 | — | — | pH 8, 25 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant H185A, dihydroorotate |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant H185A | Plasmodium falciparum | ubiquinone-1 | 7.3 | 0.022 | 330 calc. | pH 8, 25 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant H185A, ubiquinone-1 |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant H185A | Plasmodium falciparum | ubiquinone-1 | 2.3 | 0.041 | 56 calc. | pH 8, 4 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant H185A, ubiquinone-1 |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant I272A | Plasmodium falciparum | decylubiquinone | 1.8 | 0.012 | 150 calc. | pH 8, 25 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant I272A, decylubiquinone |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant I272A | Plasmodium falciparum | dihydroorotate | 0.083 | — | — | pH 8, 25 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant I272A, dihydroorotate |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant I272A | Plasmodium falciparum | ubiquinone-1 | 1.5 | 0.0078 | 190 calc. | pH 8, 25 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant I272A, ubiquinone-1 |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant I272A | Plasmodium falciparum | ubiquinone-1 | 1.1 | 0.015 | 73 calc. | pH 8, 4 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant I272A, ubiquinone-1 |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant L531A | Plasmodium falciparum | decylubiquinone | 8.6 | 0.016 | 540 calc. | pH 8, 25 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant L531A, decylubiquinone |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant L531A | Plasmodium falciparum | dihydroorotate | 0.25 | — | — | pH 8, 25 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant L531A, dihydroorotate |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant L531A | Plasmodium falciparum | ubiquinone-1 | 5.1 | 0.017 | 300 calc. | pH 8, 25 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant L531A, ubiquinone-1 |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant R265A | Plasmodium falciparum | decylubiquinone | 5 | 0.026 | 190 calc. | pH 8, 25 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant R265A, decylubiquinone |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant R265A | Plasmodium falciparum | dihydroorotate | 0.44 | — | — | pH 8, 25 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant R265A, dihydroorotate |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant R265A | Plasmodium falciparum | ubiquinone-1 | 3.1 | 0.038 | 82 calc. | pH 8, 25 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant R265A, ubiquinone-1 |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant R265A | Plasmodium falciparum | ubiquinone-1 | 1.7 | 0.021 | 81 calc. | pH 8, 4 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant R265A, ubiquinone-1 |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant Y528A | Plasmodium falciparum | decylubiquinone | 0.12 | 0.0088 | 14 calc. | pH 8, 25 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant Y528A, decylubiquinone |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant Y528A | Plasmodium falciparum | dihydroorotate | 0.1 | — | — | pH 8, 25 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant Y528A, dihydroorotate |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant Y528A | Plasmodium falciparum | ubiquinone-1 | 0.19 | 0.016 | 12 calc. | pH 8, 25 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant Y528A, ubiquinone-1 |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant Y528A | Plasmodium falciparum | ubiquinone-1 | 0.1 | 0.037 | 2.7 calc. | pH 8, 4 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant Y528A, ubiquinone-1 |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant Y528F | Plasmodium falciparum | decylubiquinone | 1.2 | 0.053 | 23 calc. | pH 8, 25 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant Y528F, decylubiquinone |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant Y528F | Plasmodium falciparum | dihydroorotate | 0.63 | — | — | pH 8, 25 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant Y528F, dihydroorotate |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant Y528F | Plasmodium falciparum | ubiquinone-1 | 1.9 | 0.02 | 95 calc. | pH 8, 25 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant Y528F, ubiquinone-1 |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant Y528W | Plasmodium falciparum | decylubiquinone | 6.8 | 0.045 | 150 calc. | pH 8, 25 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant Y528W, decylubiquinone |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant Y528W | Plasmodium falciparum | dihydroorotate | 0.18 | — | — | pH 8, 25 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant Y528W, dihydroorotate |
| pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase)variant Y528W | Plasmodium falciparum | ubiquinone-1 | 5.1 | 0.048 | 110 calc. | pH 8, 25 °C | Open record: pfDHODH (Plasmodium falciparum dihydroorotate dehydrogenase) variant Y528W, ubiquinone-1 |