Values CatLog read from this paper

The role of kinase domain dimerization in EGFR activation

PMID 41421344doi:10.1016/j.str.2025.11.017Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 9 records (18 values) from this paper: Epidermal growth factor receptor (EGFR) kinase from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 2.7.10.1

Records read from this paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Open record
Epidermal growth factor receptor (EGFR) kinasevariant K708C/C781S	Homo sapiens	AQT0001 peptide (AssayQuant PhosphoSens EGFR Sox-based peptide sensor)	0.19	—	—	pH 7.5, 30 °C	Open record: Epidermal growth factor receptor (EGFR) kinase variant K708C/C781S, AQT0001 peptide (AssayQuant PhosphoSens EGFR Sox-based peptide sensor)
Epidermal growth factor receptor (EGFR) kinasevariant K929C	Homo sapiens	AQT0001 peptide (AssayQuant PhosphoSens EGFR Sox-based peptide sensor)	0.3	—	—	pH 7.5, 30 °C	Open record: Epidermal growth factor receptor (EGFR) kinase variant K929C, AQT0001 peptide (AssayQuant PhosphoSens EGFR Sox-based peptide sensor)
Epidermal growth factor receptor (EGFR) kinasevariant K929C	Homo sapiens	AQT0001 peptide (AssayQuant PhosphoSens EGFR Sox-based peptide sensor)	0.18	—	—	pH 7.5, 30 °C	Open record: Epidermal growth factor receptor (EGFR) kinase variant K929C, AQT0001 peptide (AssayQuant PhosphoSens EGFR Sox-based peptide sensor)
Epidermal growth factor receptor (EGFR) kinasevariant KDD ICRΔC	Homo sapiens	adenosine 5'-triphosphate	—	0.023	987	pH 7.5, 30 °C	Open record: Epidermal growth factor receptor (EGFR) kinase variant KDD ICRΔC, adenosine 5'-triphosphate
Epidermal growth factor receptor (EGFR) kinasevariant KDD ICRΔC	Homo sapiens	AQT0001 peptide (AssayQuant PhosphoSens EGFR Sox-based peptide sensor)	22.7	0.03	757	pH 7.5, 30 °C	Open record: Epidermal growth factor receptor (EGFR) kinase variant KDD ICRΔC, AQT0001 peptide (AssayQuant PhosphoSens EGFR Sox-based peptide sensor)
Epidermal growth factor receptor (EGFR) kinasevariant KDD ICRΔC (L858’R)	Homo sapiens	adenosine 5'-triphosphate	—	0.084	498	pH 7.5, 30 °C	Open record: Epidermal growth factor receptor (EGFR) kinase variant KDD ICRΔC (L858’R), adenosine 5'-triphosphate
Epidermal growth factor receptor (EGFR) kinasevariant KDD ICRΔC (L858’R)	Homo sapiens	AQT0001 peptide (AssayQuant PhosphoSens EGFR Sox-based peptide sensor)	41.8	0.048	871	pH 7.5, 30 °C	Open record: Epidermal growth factor receptor (EGFR) kinase variant KDD ICRΔC (L858’R), AQT0001 peptide (AssayQuant PhosphoSens EGFR Sox-based peptide sensor)
Epidermal growth factor receptor (EGFR) kinasevariant S-S dimer	Homo sapiens	adenosine 5'-triphosphate	—	0.082	274	pH 7.5, 30 °C	Open record: Epidermal growth factor receptor (EGFR) kinase variant S-S dimer, adenosine 5'-triphosphate
Epidermal growth factor receptor (EGFR) kinasevariant S-S dimer	Homo sapiens	AQT0001 peptide (AssayQuant PhosphoSens EGFR Sox-based peptide sensor)	22.5	0.032	703	pH 7.5, 30 °C	Open record: Epidermal growth factor receptor (EGFR) kinase variant S-S dimer, AQT0001 peptide (AssayQuant PhosphoSens EGFR Sox-based peptide sensor)