Values CatLog read from this paper
The 5'-Isobutyryl Ester Prodrug of 4'-Thiouridine Inhibits SARS-CoV‑2 Replication in Culture and in a Syrian Hamster Infection Model
PMID 42540126doi:10.1021/acsomega.6c00102Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 3 records (5 values) from this paper: NSP10/14 exonuclease complex, RNA-dependent RNA polymerase (RdRp) NSP12/7/8 complex from SARS-CoV-2.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| NSP10/14 exonuclease complex | SARS-CoV-2 | 4'-thiouridine 5'-monophosphate at the 3'-terminus of the RNA primer strand | 18 | — | — | Open record: NSP10/14 exonuclease complex, 4'-thiouridine 5'-monophosphate at the 3'-terminus of the RNA primer strand | |
| NSP10/14 exonuclease complex | SARS-CoV-2 | dsRNA with 3'-terminal uridine monophosphate (uridine-MP21) | 21 | — | — | Open record: NSP10/14 exonuclease complex, dsRNA with 3'-terminal uridine monophosphate (uridine-MP21) | |
| RNA-dependent RNA polymerase (RdRp) NSP12/7/8 complex | SARS-CoV-2 | 4'-thiouridine 5'-triphosphate | 22 | 0.058 | 380 | Open record: RNA-dependent RNA polymerase (RdRp) NSP12/7/8 complex, 4'-thiouridine 5'-triphosphate |