Values CatLog read from this paper
Structure-function analysis of vitamin D 24-hydroxylase (CYP24A1) by site-directed mutagenesis: amino acid residues responsible for species-based difference of CYP24A1 between humans and rats
PMID 16617161doi:10.1124/mol.106.023275Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 9 records (27 values) from this paper: CYP24A1 from Rattus norvegicus, Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| CYP24A1 | Homo sapiens | 1α,25-dihydroxyvitamin D3 | 0.0072 | 3.5 × 10⁻⁴ | 20 | pH 7.4 | Open record: CYP24A1, 1α,25-dihydroxyvitamin D3 |
| CYP24A1 | Rattus norvegicus | 1α,25-dihydroxyvitamin D3 | 0.0043 | 1.9 × 10⁻⁴ | 23 | pH 7.4 | Open record: CYP24A1, 1α,25-dihydroxyvitamin D3 |
| CYP24A1variant I500F | Rattus norvegicus | 1α,25-dihydroxyvitamin D3 | 0.0018 | 0.00114 | 1.7 | pH 7.4 | Open record: CYP24A1 variant I500F, 1α,25-dihydroxyvitamin D3 |
| CYP24A1variant I500L | Rattus norvegicus | 1α,25-dihydroxyvitamin D3 | 8.3 × 10⁻⁴ | 3 × 10⁻⁴ | 2.8 | pH 7.4 | Open record: CYP24A1 variant I500L, 1α,25-dihydroxyvitamin D3 |
| CYP24A1variant I500T | Rattus norvegicus | 1α,25-dihydroxyvitamin D3 | 0.002 | 1.4 × 10⁻⁴ | 15.3 | pH 7.4 | Open record: CYP24A1 variant I500T, 1α,25-dihydroxyvitamin D3 |
| CYP24A1variant T416A | Rattus norvegicus | 1α,25-dihydroxyvitamin D3 | 0.0042 | 2.4 × 10⁻⁴ | 20 | pH 7.4 | Open record: CYP24A1 variant T416A, 1α,25-dihydroxyvitamin D3 |
| CYP24A1variant T416M | Rattus norvegicus | 1α,25-dihydroxyvitamin D3 | 0.0035 | 6.6 × 10⁻⁴ | 5.3 | pH 7.4 | Open record: CYP24A1 variant T416M, 1α,25-dihydroxyvitamin D3 |
| CYP24A1variant T416S | Rattus norvegicus | 1α,25-dihydroxyvitamin D3 | 0.005 | 2.2 × 10⁻⁴ | 23 | pH 7.4 | Open record: CYP24A1 variant T416S, 1α,25-dihydroxyvitamin D3 |
| CYP24A1variant T416V | Rattus norvegicus | 1α,25-dihydroxyvitamin D3 | 0.012 | 0.00104 | 11.8 | pH 7.4 | Open record: CYP24A1 variant T416V, 1α,25-dihydroxyvitamin D3 |