Values CatLog read from this paper
Structural and Kinetic Basis for the Rational Design of Next-Generation β-Lactamase Inhibitors
PMID 41838618doi:10.1021/acs.jmedchem.5c03315Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 8 records (24 values) from this paper: Pseudomonas-derived cephalosporinase-3 (PDC-3, class C β-lactamase AmpC) from Pseudomonas aeruginosa.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| Pseudomonas-derived cephalosporinase-3 (PDC-3, class C β-lactamase AmpC) | Pseudomonas aeruginosa | nitrocefin | 77 | 0.025 | 3.1 × 10³ | pH 5.2 | Open record: Pseudomonas-derived cephalosporinase-3 (PDC-3, class C β-lactamase AmpC), nitrocefin |
| Pseudomonas-derived cephalosporinase-3 (PDC-3, class C β-lactamase AmpC) | Pseudomonas aeruginosa | nitrocefin | 152 | 0.028 | 5.4 × 10³ | pH 7.2 | Open record: Pseudomonas-derived cephalosporinase-3 (PDC-3, class C β-lactamase AmpC), nitrocefin |
| Pseudomonas-derived cephalosporinase-3 (PDC-3, class C β-lactamase AmpC) | Pseudomonas aeruginosa | nitrocefin | 222 | 0.024 | 9.3 × 10³ | pH 8 | Open record: Pseudomonas-derived cephalosporinase-3 (PDC-3, class C β-lactamase AmpC), nitrocefin |
| Pseudomonas-derived cephalosporinase-3 (PDC-3, class C β-lactamase AmpC) | Pseudomonas aeruginosa | nitrocefin | 267 | 0.021 | 1.27 × 10⁴ | pH 9.5 | Open record: Pseudomonas-derived cephalosporinase-3 (PDC-3, class C β-lactamase AmpC), nitrocefin |
| Pseudomonas-derived cephalosporinase-3 (PDC-3, class C β-lactamase AmpC)variant R349A | Pseudomonas aeruginosa | nitrocefin | 21 | 0.004 | 5.3 × 10³ | pH 5.2 | Open record: Pseudomonas-derived cephalosporinase-3 (PDC-3, class C β-lactamase AmpC) variant R349A, nitrocefin |
| Pseudomonas-derived cephalosporinase-3 (PDC-3, class C β-lactamase AmpC)variant R349A | Pseudomonas aeruginosa | nitrocefin | 85 | 0.0101 | 8.4 × 10³ | pH 7.2 | Open record: Pseudomonas-derived cephalosporinase-3 (PDC-3, class C β-lactamase AmpC) variant R349A, nitrocefin |
| Pseudomonas-derived cephalosporinase-3 (PDC-3, class C β-lactamase AmpC)variant R349A | Pseudomonas aeruginosa | nitrocefin | 114 | 0.0126 | 9 × 10³ | pH 8 | Open record: Pseudomonas-derived cephalosporinase-3 (PDC-3, class C β-lactamase AmpC) variant R349A, nitrocefin |
| Pseudomonas-derived cephalosporinase-3 (PDC-3, class C β-lactamase AmpC)variant R349A | Pseudomonas aeruginosa | nitrocefin | 122 | 0.0108 | 1.13 × 10⁴ | pH 9.5 | Open record: Pseudomonas-derived cephalosporinase-3 (PDC-3, class C β-lactamase AmpC) variant R349A, nitrocefin |