Values CatLog read from this paper
The role of N286 and D320 in the reaction mechanism of human dihydrolipoamide dehydrogenase (E3) center domain
PMID 17171578doi:10.1007/s11373-006-9136-0Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 16 records (24 values) from this paper: dihydrolipoamide dehydrogenase (E3) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 8 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| dihydrolipoamide dehydrogenase (E3) | Homo sapiens | dihydrolipoamide | 505 | 0.38 | 1.3 × 10³ calc. | pH 7.4 | Open record: dihydrolipoamide dehydrogenase (E3), dihydrolipoamide |
| dihydrolipoamide dehydrogenase (E3) | Homo sapiens | lipoamide | — | 0.56 | — | pH 6.8 | Open record: dihydrolipoamide dehydrogenase (E3), lipoamide |
| dihydrolipoamide dehydrogenase (E3) | Homo sapiens | NAD+ | — | 0.22 | — | pH 7.4 | Open record: dihydrolipoamide dehydrogenase (E3), NAD+ |
| dihydrolipoamide dehydrogenase (E3) | Homo sapiens | NADH | 519 | 0.04 | 1.3 × 10⁴ calc. | pH 6.8 | Open record: dihydrolipoamide dehydrogenase (E3), NADH |
| dihydrolipoamide dehydrogenase (E3)variant D320N | Homo sapiens | dihydrolipoamide | 107 | 1.21 | 88.4 calc. | pH 7.4 | Open record: dihydrolipoamide dehydrogenase (E3) variant D320N, dihydrolipoamide |
| dihydrolipoamide dehydrogenase (E3)variant D320N | Homo sapiens | lipoamide | — | 0.46 | — | pH 6.8 | Open record: dihydrolipoamide dehydrogenase (E3) variant D320N, lipoamide |
| dihydrolipoamide dehydrogenase (E3)variant D320N | Homo sapiens | NAD+ | — | 0.34 | — | pH 7.4 | Open record: dihydrolipoamide dehydrogenase (E3) variant D320N, NAD+ |
| dihydrolipoamide dehydrogenase (E3)variant D320N | Homo sapiens | NADH | 67 | 0.24 | 280 calc. | pH 6.8 | Open record: dihydrolipoamide dehydrogenase (E3) variant D320N, NADH |
| dihydrolipoamide dehydrogenase (E3)variant N286D | Homo sapiens | dihydrolipoamide | 159 | 0.7 | 230 calc. | pH 7.4 | Open record: dihydrolipoamide dehydrogenase (E3) variant N286D, dihydrolipoamide |
| dihydrolipoamide dehydrogenase (E3)variant N286D | Homo sapiens | lipoamide | — | 0.07 | — | pH 6.8 | Open record: dihydrolipoamide dehydrogenase (E3) variant N286D, lipoamide |
| dihydrolipoamide dehydrogenase (E3)variant N286D | Homo sapiens | NAD+ | — | 0.3 | — | pH 7.4 | Open record: dihydrolipoamide dehydrogenase (E3) variant N286D, NAD+ |
| dihydrolipoamide dehydrogenase (E3)variant N286D | Homo sapiens | NADH | 134 | 0.13 | 1.0 × 10³ calc. | pH 6.8 | Open record: dihydrolipoamide dehydrogenase (E3) variant N286D, NADH |
| dihydrolipoamide dehydrogenase (E3)variant N286Q | Homo sapiens | dihydrolipoamide | 116 | 0.2 | 580 calc. | pH 7.4 | Open record: dihydrolipoamide dehydrogenase (E3) variant N286Q, dihydrolipoamide |
| dihydrolipoamide dehydrogenase (E3)variant N286Q | Homo sapiens | lipoamide | — | 0.05 | — | pH 6.8 | Open record: dihydrolipoamide dehydrogenase (E3) variant N286Q, lipoamide |
| dihydrolipoamide dehydrogenase (E3)variant N286Q | Homo sapiens | NAD+ | — | 0.16 | — | pH 7.4 | Open record: dihydrolipoamide dehydrogenase (E3) variant N286Q, NAD+ |
| dihydrolipoamide dehydrogenase (E3)variant N286Q | Homo sapiens | NADH | 148 | 0.14 | 1.1 × 10³ calc. | pH 6.8 | Open record: dihydrolipoamide dehydrogenase (E3) variant N286Q, NADH |