EC 1.8.1.4: dihydrolipoyl dehydrogenase
OxidoreductasesOpen in Browse
CatLog read 61 records for EC 1.8.1.4 from 5 papers, for 3 organisms. Names in these papers: dihydrolipoamide dehydrogenase (E3), dihydrolipoamide dehydrogenase, lipoamide dehydrogenase (L-protein).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 121 records for EC 1.8.1.4 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.8.1.4 in Browse.
Papers
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| dihydrolipoamide dehydrogenase | Haloferax volcanii | DL-dihydrolipoamide2 M KCl | — | 0.0269 | — | pH 7, 30 °C | PMID 9346289 | Open record: dihydrolipoamide dehydrogenase, DL-dihydrolipoamide |
| dihydrolipoamide dehydrogenase | Haloferax volcanii | DL-dihydrolipoamideno KCl | — | 0.0274 | — | pH 7, 30 °C | PMID 9346289 | Open record: dihydrolipoamide dehydrogenase, DL-dihydrolipoamide |
| dihydrolipoamide dehydrogenase | Haloferax volcanii | NAD+2 M KCl | — | 0.156 | — | pH 7, 30 °C | PMID 9346289 | Open record: dihydrolipoamide dehydrogenase, NAD+ |
| dihydrolipoamide dehydrogenase | Haloferax volcanii | NAD+no KCl | — | 0.186 | — | pH 7, 30 °C | PMID 9346289 | Open record: dihydrolipoamide dehydrogenase, NAD+ |
| dihydrolipoamide dehydrogenasevariant E423A | Haloferax volcanii | DL-dihydrolipoamide2 M KCl | — | 0.0107 | — | pH 7, 30 °C | PMID 9346289 | Open record: dihydrolipoamide dehydrogenase variant E423A, DL-dihydrolipoamide |
| dihydrolipoamide dehydrogenasevariant E423A | Haloferax volcanii | DL-dihydrolipoamideno KCl | — | 0.0243 | — | pH 7, 30 °C | PMID 9346289 | Open record: dihydrolipoamide dehydrogenase variant E423A, DL-dihydrolipoamide |
| dihydrolipoamide dehydrogenasevariant E423A | Haloferax volcanii | NAD+2 M KCl | — | 0.215 | — | pH 7, 30 °C | PMID 9346289 | Open record: dihydrolipoamide dehydrogenase variant E423A, NAD+ |
| dihydrolipoamide dehydrogenasevariant E423A | Haloferax volcanii | NAD+no KCl | — | 0.182 | — | pH 7, 30 °C | PMID 9346289 | Open record: dihydrolipoamide dehydrogenase variant E423A, NAD+ |
| dihydrolipoamide dehydrogenasevariant E423D | Haloferax volcanii | DL-dihydrolipoamide2 M KCl | — | 0.0266 | — | pH 7, 30 °C | PMID 9346289 | Open record: dihydrolipoamide dehydrogenase variant E423D, DL-dihydrolipoamide |
| dihydrolipoamide dehydrogenasevariant E423D | Haloferax volcanii | DL-dihydrolipoamideno KCl | — | 0.0157 | — | pH 7, 30 °C | PMID 9346289 | Open record: dihydrolipoamide dehydrogenase variant E423D, DL-dihydrolipoamide |
| dihydrolipoamide dehydrogenasevariant E423D | Haloferax volcanii | NAD+2 M KCl | — | 0.199 | — | pH 7, 30 °C | PMID 9346289 | Open record: dihydrolipoamide dehydrogenase variant E423D, NAD+ |
| dihydrolipoamide dehydrogenasevariant E423D | Haloferax volcanii | NAD+no KCl | — | 0.292 | — | pH 7, 30 °C | PMID 9346289 | Open record: dihydrolipoamide dehydrogenase variant E423D, NAD+ |
| dihydrolipoamide dehydrogenasevariant E423Q | Haloferax volcanii | DL-dihydrolipoamide2 M KCl | — | 0.0228 | — | pH 7, 30 °C | PMID 9346289 | Open record: dihydrolipoamide dehydrogenase variant E423Q, DL-dihydrolipoamide |
| dihydrolipoamide dehydrogenasevariant E423Q | Haloferax volcanii | DL-dihydrolipoamideno KCl | — | 0.0177 | — | pH 7, 30 °C | PMID 9346289 | Open record: dihydrolipoamide dehydrogenase variant E423Q, DL-dihydrolipoamide |
| dihydrolipoamide dehydrogenasevariant E423Q | Haloferax volcanii | NAD+2 M KCl | — | 0.203 | — | pH 7, 30 °C | PMID 9346289 | Open record: dihydrolipoamide dehydrogenase variant E423Q, NAD+ |
| dihydrolipoamide dehydrogenasevariant E423Q | Haloferax volcanii | NAD+no KCl | — | 0.288 | — | pH 7, 30 °C | PMID 9346289 | Open record: dihydrolipoamide dehydrogenase variant E423Q, NAD+ |
| dihydrolipoamide dehydrogenasevariant E423S | Haloferax volcanii | DL-dihydrolipoamide2 M KCl | — | 0.023 | — | pH 7, 30 °C | PMID 9346289 | Open record: dihydrolipoamide dehydrogenase variant E423S, DL-dihydrolipoamide |
| dihydrolipoamide dehydrogenasevariant E423S | Haloferax volcanii | DL-dihydrolipoamideno KCl | — | 0.0364 | — | pH 7, 30 °C | PMID 9346289 | Open record: dihydrolipoamide dehydrogenase variant E423S, DL-dihydrolipoamide |
| dihydrolipoamide dehydrogenasevariant E423S | Haloferax volcanii | NAD+2 M KCl | — | 0.211 | — | pH 7, 30 °C | PMID 9346289 | Open record: dihydrolipoamide dehydrogenase variant E423S, NAD+ |
| dihydrolipoamide dehydrogenasevariant E423S | Haloferax volcanii | NAD+no KCl | — | 0.312 | — | pH 7, 30 °C | PMID 9346289 | Open record: dihydrolipoamide dehydrogenase variant E423S, NAD+ |
| dihydrolipoamide dehydrogenase (E3) | Homo sapiens | 1,2-diselenolane-3-pentanoic acid | 4.7 | 0.71 | 6.6 | pH 6.3, 37 °C | PMID 10218658 | Open record: dihydrolipoamide dehydrogenase (E3), 1,2-diselenolane-3-pentanoic acid |
| dihydrolipoamide dehydrogenase (E3) | Homo sapiens | dihydrolipoamide | 505 | 0.38 | 1.3 × 10³ calc. | pH 7.4 | PMID 17171578 | Open record: dihydrolipoamide dehydrogenase (E3), dihydrolipoamide |
| dihydrolipoamide dehydrogenase (E3) | Homo sapiens | DL-dihydrolipoamide | 567 | 0.88 | 646 | PMID 10336857 | Open record: dihydrolipoamide dehydrogenase (E3), DL-dihydrolipoamide | |
| dihydrolipoamide dehydrogenase (E3) | Homo sapiens | DL-Lipoamide | 719.2 | 1.39 | 517.4 | pH 6.3, 37 °C | PMID 10218658 | Open record: dihydrolipoamide dehydrogenase (E3), DL-Lipoamide |
| dihydrolipoamide dehydrogenase (E3) | Homo sapiens | DL-lipoamide | 649 | 2.25 | 288 | PMID 10336857 | Open record: dihydrolipoamide dehydrogenase (E3), DL-lipoamide | |
| dihydrolipoamide dehydrogenase (E3) | Homo sapiens | lipoamide | — | 0.56 | — | pH 6.8 | PMID 17171578 | Open record: dihydrolipoamide dehydrogenase (E3), lipoamide |
| dihydrolipoamide dehydrogenase (E3) | Homo sapiens | NAD+ | 574 | 0.4 | 1436 | PMID 10336857 | Open record: dihydrolipoamide dehydrogenase (E3), NAD+ | |
| dihydrolipoamide dehydrogenase (E3) | Homo sapiens | NAD+ | — | 0.22 | — | pH 7.4 | PMID 17171578 | Open record: dihydrolipoamide dehydrogenase (E3), NAD+ |
| dihydrolipoamide dehydrogenase (E3) | Homo sapiens | NADH | 340 | 0.25 | 1.36 × 10³ | PMID 10336857 | Open record: dihydrolipoamide dehydrogenase (E3), NADH | |
| dihydrolipoamide dehydrogenase (E3) | Homo sapiens | NADH | 519 | 0.04 | 1.3 × 10⁴ calc. | pH 6.8 | PMID 17171578 | Open record: dihydrolipoamide dehydrogenase (E3), NADH |
| dihydrolipoamide dehydrogenase (E3) | Homo sapiens | R-Lipoic acid | 9.7 | 0.53 | 18.4 | pH 6.3, 37 °C | PMID 10218658 | Open record: dihydrolipoamide dehydrogenase (E3), R-Lipoic acid |
| dihydrolipoamide dehydrogenase (E3) | Homo sapiens | S-Lipoic acid | 7.1 | 9.1 | 0.12 | pH 6.3, 37 °C | PMID 10218658 | Open record: dihydrolipoamide dehydrogenase (E3), S-Lipoic acid |
| dihydrolipoamide dehydrogenase (E3)variant D320N | Homo sapiens | dihydrolipoamide | 107 | 1.21 | 88.4 calc. | pH 7.4 | PMID 17171578 | Open record: dihydrolipoamide dehydrogenase (E3) variant D320N, dihydrolipoamide |
| dihydrolipoamide dehydrogenase (E3)variant D320N | Homo sapiens | lipoamide | — | 0.46 | — | pH 6.8 | PMID 17171578 | Open record: dihydrolipoamide dehydrogenase (E3) variant D320N, lipoamide |
| dihydrolipoamide dehydrogenase (E3)variant D320N | Homo sapiens | NAD+ | — | 0.34 | — | pH 7.4 | PMID 17171578 | Open record: dihydrolipoamide dehydrogenase (E3) variant D320N, NAD+ |
| dihydrolipoamide dehydrogenase (E3)variant D320N | Homo sapiens | NADH | 67 | 0.24 | 280 calc. | pH 6.8 | PMID 17171578 | Open record: dihydrolipoamide dehydrogenase (E3) variant D320N, NADH |
| dihydrolipoamide dehydrogenase (E3)variant E192Q | Homo sapiens | DL-dihydrolipoamide | 29.7 | 0.12 | 244.4 | PMID 10336857 | Open record: dihydrolipoamide dehydrogenase (E3) variant E192Q, DL-dihydrolipoamide | |
| dihydrolipoamide dehydrogenase (E3)variant E192Q | Homo sapiens | DL-lipoamide | 81.3 | 0.31 | 261 | PMID 10336857 | Open record: dihydrolipoamide dehydrogenase (E3) variant E192Q, DL-lipoamide | |
| dihydrolipoamide dehydrogenase (E3)variant E192Q | Homo sapiens | NAD+ | 30 | 0.31 | 95.5 | PMID 10336857 | Open record: dihydrolipoamide dehydrogenase (E3) variant E192Q, NAD+ | |
| dihydrolipoamide dehydrogenase (E3)variant E192Q | Homo sapiens | NADH | 26.2 | 0.071 | 368 | PMID 10336857 | Open record: dihydrolipoamide dehydrogenase (E3) variant E192Q, NADH | |
| dihydrolipoamide dehydrogenase (E3)variant K54E | Homo sapiens | DL-lipoamide | 23 | 5 | 4.59 | PMID 10336857 | Open record: dihydrolipoamide dehydrogenase (E3) variant K54E, DL-lipoamide | |
| dihydrolipoamide dehydrogenase (E3)variant N286D | Homo sapiens | dihydrolipoamide | 159 | 0.7 | 230 calc. | pH 7.4 | PMID 17171578 | Open record: dihydrolipoamide dehydrogenase (E3) variant N286D, dihydrolipoamide |
| dihydrolipoamide dehydrogenase (E3)variant N286D | Homo sapiens | lipoamide | — | 0.07 | — | pH 6.8 | PMID 17171578 | Open record: dihydrolipoamide dehydrogenase (E3) variant N286D, lipoamide |
| dihydrolipoamide dehydrogenase (E3)variant N286D | Homo sapiens | NAD+ | — | 0.3 | — | pH 7.4 | PMID 17171578 | Open record: dihydrolipoamide dehydrogenase (E3) variant N286D, NAD+ |
| dihydrolipoamide dehydrogenase (E3)variant N286D | Homo sapiens | NADH | 134 | 0.13 | 1.0 × 10³ calc. | pH 6.8 | PMID 17171578 | Open record: dihydrolipoamide dehydrogenase (E3) variant N286D, NADH |
| dihydrolipoamide dehydrogenase (E3)variant N286Q | Homo sapiens | dihydrolipoamide | 116 | 0.2 | 580 calc. | pH 7.4 | PMID 17171578 | Open record: dihydrolipoamide dehydrogenase (E3) variant N286Q, dihydrolipoamide |
| dihydrolipoamide dehydrogenase (E3)variant N286Q | Homo sapiens | lipoamide | — | 0.05 | — | pH 6.8 | PMID 17171578 | Open record: dihydrolipoamide dehydrogenase (E3) variant N286Q, lipoamide |
| dihydrolipoamide dehydrogenase (E3)variant N286Q | Homo sapiens | NAD+ | — | 0.16 | — | pH 7.4 | PMID 17171578 | Open record: dihydrolipoamide dehydrogenase (E3) variant N286Q, NAD+ |
| dihydrolipoamide dehydrogenase (E3)variant N286Q | Homo sapiens | NADH | 148 | 0.14 | 1.1 × 10³ calc. | pH 6.8 | PMID 17171578 | Open record: dihydrolipoamide dehydrogenase (E3) variant N286Q, NADH |
| dihydrolipoamide dehydrogenase (E3)variant S53K/K54S | Homo sapiens | DL-dihydrolipoamide | 8.5 | 0.05 | 160 | PMID 10336857 | Open record: dihydrolipoamide dehydrogenase (E3) variant S53K/K54S, DL-dihydrolipoamide | |
| dihydrolipoamide dehydrogenase (E3)variant S53K/K54S | Homo sapiens | DL-lipoamide | 14.4 | 0.63 | 23 | PMID 10336857 | Open record: dihydrolipoamide dehydrogenase (E3) variant S53K/K54S, DL-lipoamide | |
| dihydrolipoamide dehydrogenase (E3)variant S53K/K54S | Homo sapiens | NAD+ | 6.75 | 0.55 | 12.2 | PMID 10336857 | Open record: dihydrolipoamide dehydrogenase (E3) variant S53K/K54S, NAD+ | |
| dihydrolipoamide dehydrogenase (E3)variant S53K/K54S | Homo sapiens | NADH | 19.8 | 0.13 | 158 | PMID 10336857 | Open record: dihydrolipoamide dehydrogenase (E3) variant S53K/K54S, NADH | |
| lipoamide dehydrogenase (L-protein) | pea | H-protein | 345 | 0.027 | 1.3 × 10⁴ | pH 7.5, 30 °C | PMID 10806385 | Open record: lipoamide dehydrogenase (L-protein), H-protein |
| lipoamide dehydrogenase (L-protein) | pea | H55-102 | 298 | 0.042 | 7 × 10³ | pH 7.5, 30 °C | PMID 10806385 | Open record: lipoamide dehydrogenase (L-protein), H55-102 |
| lipoamide dehydrogenase (L-protein) | pea | H55-66 | 319 | 0.062 | 5 × 10³ | pH 7.5, 30 °C | PMID 10806385 | Open record: lipoamide dehydrogenase (L-protein), H55-66 |
| lipoamide dehydrogenase (L-protein) | pea | N alpha-(benzyloxycarbonyl)-N omega-(d,l-1,2-dithiolane-3-pentanoyl)-L-lysine | 300 | 0.17 | 3.5 × 10³ | pH 7.5, 30 °C | PMID 10806385 | Open record: lipoamide dehydrogenase (L-protein), N alpha-(benzyloxycarbonyl)-N omega-(d,l-1,2-dithiolane-3-pentanoyl)-L-lysine |
| lipoamide dehydrogenase (L-protein) | pea | N alpha-(d,l-1,2-dithiolane-3-pentanoyl)-N-[Tris(hydroxymethyl)methyl]glycinamide | 350 | 0.13 | 4.6 × 10³ | pH 7.5, 30 °C | PMID 10806385 | Open record: lipoamide dehydrogenase (L-protein), N alpha-(d,l-1,2-dithiolane-3-pentanoyl)-N-[Tris(hydroxymethyl)methyl]glycinamide |
| lipoamide dehydrogenase (L-protein) | pea | N gamma-(d,l-1,2-dithiolane-3-pentanoyl)-N-[Tris(hydroxymethyl)methyl]butanamide | 380 | 0.155 | 4.8 × 10³ | pH 7.5, 30 °C | PMID 10806385 | Open record: lipoamide dehydrogenase (L-protein), N gamma-(d,l-1,2-dithiolane-3-pentanoyl)-N-[Tris(hydroxymethyl)methyl]butanamide |
| lipoamide dehydrogenase (L-protein) | pea | N gamma-[(R)-1,2-dithiolane-3-pentanoyl]-N-[Tris(hydroxymethyl)methyl]butanamide | 383 | 0.086 | 4.4 × 10³ | pH 7.5, 30 °C | PMID 10806385 | Open record: lipoamide dehydrogenase (L-protein), N gamma-[(R)-1,2-dithiolane-3-pentanoyl]-N-[Tris(hydroxymethyl)methyl]butanamide |
| lipoamide dehydrogenase (L-protein) | pea | R,S-lipoamide | 190 | 0.5 | 760 | pH 7.5, 30 °C | PMID 10806385 | Open record: lipoamide dehydrogenase (L-protein), R,S-lipoamide |