Values CatLog read from this paper
Human Cytosolic and Mitochondrial Serine Hydroxymethyltransferase Isoforms in Comparison: Full Kinetic Characterization and Substrate Inhibition Properties
PMID 30500180doi:10.1021/acs.biochem.8b01074Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 45 records (45 values) from this paper: SHMT2 (mitochondrial serine hydroxymethyltransferase), SHMT1 (cytosolic serine hydroxymethyltransferase) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| SHMT1 (cytosolic serine hydroxymethyltransferase) | Homo sapiens | 5,10-methylenetetrahydrofolate | — | 0.291 | — | pH 8.8, 30 °C | Open record: SHMT1 (cytosolic serine hydroxymethyltransferase), 5,10-methylenetetrahydrofolate |
| SHMT1 (cytosolic serine hydroxymethyltransferase) | Homo sapiens | 5,10-methylenetetrahydrofolate | — | 0.159 | — | pH 8.8, 30 °C | Open record: SHMT1 (cytosolic serine hydroxymethyltransferase), 5,10-methylenetetrahydrofolate |
| SHMT1 (cytosolic serine hydroxymethyltransferase) | Homo sapiens | 5,10-methylenetetrahydrofolate | — | — | 0.65 | pH 8.8, 30 °C | Open record: SHMT1 (cytosolic serine hydroxymethyltransferase), 5,10-methylenetetrahydrofolate |
| SHMT1 (cytosolic serine hydroxymethyltransferase) | Homo sapiens | 5,10-methylenetetrahydrofolate | — | — | 1.18 | pH 8.8, 30 °C | Open record: SHMT1 (cytosolic serine hydroxymethyltransferase), 5,10-methylenetetrahydrofolate |
| SHMT1 (cytosolic serine hydroxymethyltransferase) | Homo sapiens | glycine | 0.188 | — | — | pH 8.8, 30 °C | Open record: SHMT1 (cytosolic serine hydroxymethyltransferase), glycine |
| SHMT1 (cytosolic serine hydroxymethyltransferase) | Homo sapiens | glycine | — | 0.556 | — | pH 8.8, 30 °C | Open record: SHMT1 (cytosolic serine hydroxymethyltransferase), glycine |
| SHMT1 (cytosolic serine hydroxymethyltransferase) | Homo sapiens | glycine | — | 0.514 | — | pH 8.8, 30 °C | Open record: SHMT1 (cytosolic serine hydroxymethyltransferase), glycine |
| SHMT1 (cytosolic serine hydroxymethyltransferase) | Homo sapiens | glycine | — | — | 0.33 | pH 8.8, 30 °C | Open record: SHMT1 (cytosolic serine hydroxymethyltransferase), glycine |
| SHMT1 (cytosolic serine hydroxymethyltransferase) | Homo sapiens | glycine | — | — | 0.37 | pH 8.8, 30 °C | Open record: SHMT1 (cytosolic serine hydroxymethyltransferase), glycine |
| SHMT1 (cytosolic serine hydroxymethyltransferase) | Homo sapiens | L-serine | 6.23 | — | — | pH 7.2, 30 °C | Open record: SHMT1 (cytosolic serine hydroxymethyltransferase), L-serine |
| SHMT1 (cytosolic serine hydroxymethyltransferase) | Homo sapiens | L-serine | — | 4.8 | — | pH 7.2, 30 °C | Open record: SHMT1 (cytosolic serine hydroxymethyltransferase), L-serine |
| SHMT1 (cytosolic serine hydroxymethyltransferase) | Homo sapiens | L-serine | — | 0.131 | — | pH 7.2, 30 °C | Open record: SHMT1 (cytosolic serine hydroxymethyltransferase), L-serine |
| SHMT1 (cytosolic serine hydroxymethyltransferase) | Homo sapiens | L-serine | — | — | 1.3 | pH 7.2, 30 °C | Open record: SHMT1 (cytosolic serine hydroxymethyltransferase), L-serine |
| SHMT1 (cytosolic serine hydroxymethyltransferase) | Homo sapiens | L-serine | — | — | 47.5 | pH 7.2, 30 °C | Open record: SHMT1 (cytosolic serine hydroxymethyltransferase), L-serine |
| SHMT1 (cytosolic serine hydroxymethyltransferase) | Homo sapiens | tetrahydrofolate | — | 0.033 | — | pH 7.2, 30 °C | Open record: SHMT1 (cytosolic serine hydroxymethyltransferase), tetrahydrofolate |
| SHMT1 (cytosolic serine hydroxymethyltransferase) | Homo sapiens | tetrahydrofolate | — | 0.007 | — | pH 7.2, 30 °C | Open record: SHMT1 (cytosolic serine hydroxymethyltransferase), tetrahydrofolate |
| SHMT1 (cytosolic serine hydroxymethyltransferase) | Homo sapiens | tetrahydrofolate | — | — | 188.8 | pH 7.2, 30 °C | Open record: SHMT1 (cytosolic serine hydroxymethyltransferase), tetrahydrofolate |
| SHMT1 (cytosolic serine hydroxymethyltransferase) | Homo sapiens | tetrahydrofolate | — | — | 890.5 | pH 7.2, 30 °C | Open record: SHMT1 (cytosolic serine hydroxymethyltransferase), tetrahydrofolate |
| SHMT2 (mitochondrial serine hydroxymethyltransferase) | Homo sapiens | 5,10-methylenetetrahydrofolatelike another record | — | 0.98 | — | pH 8.8, 30 °C | Open record: SHMT2 (mitochondrial serine hydroxymethyltransferase), 5,10-methylenetetrahydrofolate |
| SHMT2 (mitochondrial serine hydroxymethyltransferase) | Homo sapiens | 5,10-methylenetetrahydrofolatelike another record | — | 0.98 | — | pH 8.8, 30 °C | Open record: SHMT2 (mitochondrial serine hydroxymethyltransferase), 5,10-methylenetetrahydrofolate |
| SHMT2 (mitochondrial serine hydroxymethyltransferase) | Homo sapiens | 5,10-methylenetetrahydrofolatelike another record | — | — | 0.52 | pH 8.8, 30 °C | Open record: SHMT2 (mitochondrial serine hydroxymethyltransferase), 5,10-methylenetetrahydrofolate |
| SHMT2 (mitochondrial serine hydroxymethyltransferase) | Homo sapiens | 5,10-methylenetetrahydrofolatelike another record | — | — | 0.52 | pH 8.8, 30 °C | Open record: SHMT2 (mitochondrial serine hydroxymethyltransferase), 5,10-methylenetetrahydrofolate |
| SHMT2 (mitochondrial serine hydroxymethyltransferase) | Homo sapiens | glycine | 0.5012 | — | — | pH 8.8, 30 °C | Open record: SHMT2 (mitochondrial serine hydroxymethyltransferase), glycine |
| SHMT2 (mitochondrial serine hydroxymethyltransferase) | Homo sapiens | glycine | — | 0.66 | — | pH 8.8, 30 °C | Open record: SHMT2 (mitochondrial serine hydroxymethyltransferase), glycine |
| SHMT2 (mitochondrial serine hydroxymethyltransferase) | Homo sapiens | glycine | — | 0.47 | — | pH 8.8, 30 °C | Open record: SHMT2 (mitochondrial serine hydroxymethyltransferase), glycine |
| SHMT2 (mitochondrial serine hydroxymethyltransferase) | Homo sapiens | glycine | — | — | 0.77 | pH 8.8, 30 °C | Open record: SHMT2 (mitochondrial serine hydroxymethyltransferase), glycine |
| SHMT2 (mitochondrial serine hydroxymethyltransferase) | Homo sapiens | glycine | — | — | 1.07 | pH 8.8, 30 °C | Open record: SHMT2 (mitochondrial serine hydroxymethyltransferase), glycine |
| SHMT2 (mitochondrial serine hydroxymethyltransferase) | Homo sapiens | L-serine | 14.17 | — | — | pH 7.2, 30 °C | Open record: SHMT2 (mitochondrial serine hydroxymethyltransferase), L-serine |
| SHMT2 (mitochondrial serine hydroxymethyltransferase) | Homo sapiens | L-serine | — | 2.2 | — | pH 7.2, 30 °C | Open record: SHMT2 (mitochondrial serine hydroxymethyltransferase), L-serine |
| SHMT2 (mitochondrial serine hydroxymethyltransferase) | Homo sapiens | L-serine | — | 0.396 | — | pH 7.2, 30 °C | Open record: SHMT2 (mitochondrial serine hydroxymethyltransferase), L-serine |
| SHMT2 (mitochondrial serine hydroxymethyltransferase) | Homo sapiens | L-serine | — | — | 6.5 | pH 7.2, 30 °C | Open record: SHMT2 (mitochondrial serine hydroxymethyltransferase), L-serine |
| SHMT2 (mitochondrial serine hydroxymethyltransferase) | Homo sapiens | L-serine | — | — | 35.8 | pH 7.2, 30 °C | Open record: SHMT2 (mitochondrial serine hydroxymethyltransferase), L-serine |
| SHMT2 (mitochondrial serine hydroxymethyltransferase) | Homo sapiens | L-serine | 13.55 | — | — | pH 7.8, 30 °C | Open record: SHMT2 (mitochondrial serine hydroxymethyltransferase), L-serine |
| SHMT2 (mitochondrial serine hydroxymethyltransferase) | Homo sapiens | L-serine | — | 0.45 | — | pH 7.8, 30 °C | Open record: SHMT2 (mitochondrial serine hydroxymethyltransferase), L-serine |
| SHMT2 (mitochondrial serine hydroxymethyltransferase) | Homo sapiens | L-serine | — | 0.158 | — | pH 7.8, 30 °C | Open record: SHMT2 (mitochondrial serine hydroxymethyltransferase), L-serine |
| SHMT2 (mitochondrial serine hydroxymethyltransferase) | Homo sapiens | L-serine | — | — | 30.2 | pH 7.8, 30 °C | Open record: SHMT2 (mitochondrial serine hydroxymethyltransferase), L-serine |
| SHMT2 (mitochondrial serine hydroxymethyltransferase) | Homo sapiens | L-serine | — | — | 85.8 | pH 7.8, 30 °C | Open record: SHMT2 (mitochondrial serine hydroxymethyltransferase), L-serine |
| SHMT2 (mitochondrial serine hydroxymethyltransferase) | Homo sapiens | tetrahydrofolate | — | 0.223 | — | pH 7.2, 30 °C | Open record: SHMT2 (mitochondrial serine hydroxymethyltransferase), tetrahydrofolate |
| SHMT2 (mitochondrial serine hydroxymethyltransferase) | Homo sapiens | tetrahydrofolate | — | 0.053 | — | pH 7.2, 30 °C | Open record: SHMT2 (mitochondrial serine hydroxymethyltransferase), tetrahydrofolate |
| SHMT2 (mitochondrial serine hydroxymethyltransferase) | Homo sapiens | tetrahydrofolate | — | — | 63.5 | pH 7.2, 30 °C | Open record: SHMT2 (mitochondrial serine hydroxymethyltransferase), tetrahydrofolate |
| SHMT2 (mitochondrial serine hydroxymethyltransferase) | Homo sapiens | tetrahydrofolate | — | — | 267.3 | pH 7.2, 30 °C | Open record: SHMT2 (mitochondrial serine hydroxymethyltransferase), tetrahydrofolate |
| SHMT2 (mitochondrial serine hydroxymethyltransferase) | Homo sapiens | tetrahydrofolate | — | 0.032 | — | pH 7.8, 30 °C | Open record: SHMT2 (mitochondrial serine hydroxymethyltransferase), tetrahydrofolate |
| SHMT2 (mitochondrial serine hydroxymethyltransferase) | Homo sapiens | tetrahydrofolate | — | 0.02 | — | pH 7.8, 30 °C | Open record: SHMT2 (mitochondrial serine hydroxymethyltransferase), tetrahydrofolate |
| SHMT2 (mitochondrial serine hydroxymethyltransferase) | Homo sapiens | tetrahydrofolate | — | — | 423 | pH 7.8, 30 °C | Open record: SHMT2 (mitochondrial serine hydroxymethyltransferase), tetrahydrofolate |
| SHMT2 (mitochondrial serine hydroxymethyltransferase) | Homo sapiens | tetrahydrofolate | — | — | 677.5 | pH 7.8, 30 °C | Open record: SHMT2 (mitochondrial serine hydroxymethyltransferase), tetrahydrofolate |