Values CatLog read from this paper
Kinetic, Thermodynamic, and Structural Analysis of Drug Resistance Mutations in Neuraminidase from the 2009 Pandemic Influenza Virus
PMID 29933553doi:10.3390/v10070339Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 6 records (18 values) from this paper: neuraminidase (NA2009) from Influenza A virus.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| neuraminidase (NA2009) | Influenza A virus | 2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid | 0.9 | 1.1 | 0.82 | 37 °C | Open record: neuraminidase (NA2009), 2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid |
| neuraminidase (NA2009)variant H275Y | Influenza A virus | 2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid | 0.054 | 1.1 | 0.048 | 37 °C | Open record: neuraminidase (NA2009) variant H275Y, 2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid |
| neuraminidase (NA2009)variant H275Y/I223V | Influenza A virus | 2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid | 0.045 | 1.3 | 0.035 | 37 °C | Open record: neuraminidase (NA2009) variant H275Y/I223V, 2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid |
| neuraminidase (NA2009)variant H275Y/S247N | Influenza A virus | 2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid | 0.1 | 3.3 | 0.031 | 37 °C | Open record: neuraminidase (NA2009) variant H275Y/S247N, 2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid |
| neuraminidase (NA2009)variant I223V | Influenza A virus | 2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid | 0.6 | 1.2 | 0.51 | 37 °C | Open record: neuraminidase (NA2009) variant I223V, 2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid |
| neuraminidase (NA2009)variant S247N | Influenza A virus | 2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid | 0.17 | 1.1 | 0.16 | 37 °C | Open record: neuraminidase (NA2009) variant S247N, 2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid |