CatLogenzyme kinetics catalog

Values CatLog read from this paper

Mimicking phosphorylation of Ser-74 on human deoxycytidine kinase selectively increases catalytic activity for dC and dC analogues

PMID 18258203doi:10.1016/j.febslet.2008.01.048Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 25 records (45 values) from this paper: deoxycytidine kinase from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 2.7.1.74, EC 2.7.1.76, EC 2.7.1.113

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
deoxycytidine kinaseHomo sapienscytarabine0.320.005954.2pH 7.5, 25 °COpen
deoxycytidine kinaseHomo sapiensdeoxyadenosine0.770.11696.6pH 7.5, 25 °COpen
deoxycytidine kinaseHomo sapiensdeoxycytidine0.040.001723.1pH 7.5, 25 °COpen
deoxycytidine kinaseHomo sapiensdeoxyguanosine0.730.24582.9pH 7.5, 25 °COpen
deoxycytidine kinaseHomo sapiensgemcitabine0.440.006271pH 7.5, 25 °COpen
deoxycytidine kinasevariant S74AHomo sapienscytarabine0.33——pH 7.5, 25 °COpen
deoxycytidine kinasevariant S74AHomo sapiensdeoxyadenosine1.12——pH 7.5, 25 °COpen
deoxycytidine kinasevariant S74AHomo sapiensdeoxycytidine0.04——pH 7.5, 25 °COpen
deoxycytidine kinasevariant S74AHomo sapiensdeoxyguanosine0.68——pH 7.5, 25 °COpen
deoxycytidine kinasevariant S74AHomo sapiensgemcitabine0.5——pH 7.5, 25 °COpen
deoxycytidine kinasevariant S74DHomo sapienscytarabine0.57——pH 7.5, 25 °COpen
deoxycytidine kinasevariant S74DHomo sapiensdeoxyadenosine1——pH 7.5, 25 °COpen
deoxycytidine kinasevariant S74DHomo sapiensdeoxycytidine0.16——pH 7.5, 25 °COpen
deoxycytidine kinasevariant S74DHomo sapiensdeoxyguanosine0.57——pH 7.5, 25 °COpen
deoxycytidine kinasevariant S74DHomo sapiensgemcitabine0.9——pH 7.5, 25 °COpen
deoxycytidine kinasevariant S74EHomo sapienscytarabine1.060.024144pH 7.5, 25 °COpen
deoxycytidine kinasevariant S74EHomo sapiensdeoxyadenosine0.690.51791.3pH 7.5, 25 °COpen
deoxycytidine kinasevariant S74EHomo sapiensdeoxycytidine0.450.008950.6pH 7.5, 25 °COpen
deoxycytidine kinasevariant S74EHomo sapiensdeoxyguanosine0.360.60180.6pH 7.5, 25 °COpen
deoxycytidine kinasevariant S74EHomo sapiensgemcitabine1.210.01580.7pH 7.5, 25 °COpen
deoxycytidine kinasevariant S74QHomo sapienscytarabine0.3——pH 7.5, 25 °COpen
deoxycytidine kinasevariant S74QHomo sapiensdeoxyadenosine0.9——pH 7.5, 25 °COpen
deoxycytidine kinasevariant S74QHomo sapiensdeoxycytidine0.04——pH 7.5, 25 °COpen
deoxycytidine kinasevariant S74QHomo sapiensdeoxyguanosine0.65——pH 7.5, 25 °COpen
deoxycytidine kinasevariant S74QHomo sapiensgemcitabine0.45——pH 7.5, 25 °COpen