Values CatLog read from this paper
Purification and kinetic characterization of recombinant human mitogen-activated protein kinase kinase kinase COT and the complexes with its cellular partner NF-kappa B1 p105
PMID 16087150doi:10.1016/j.abb.2005.06.020Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 12 records (24 values) from this paper: COT kinase (cancer osaka thyroid, MAP3K) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| COT kinase (cancer osaka thyroid, MAP3K) | Homo sapiens | adenosine 5'-triphosphate5 mM MnCl2 (5 mM Mn2+) | — | 0.02 | — | pH 7.5 | Open record: COT kinase (cancer osaka thyroid, MAP3K), adenosine 5'-triphosphate |
| COT kinase (cancer osaka thyroid, MAP3K) | Homo sapiens | adenosine 5'-triphosphate10 mM MgCl2 (10 mM Mg2+) | — | 0.39 | — | pH 7.5 | Open record: COT kinase (cancer osaka thyroid, MAP3K), adenosine 5'-triphosphate |
| COT kinase (cancer osaka thyroid, MAP3K) | Homo sapiens | adenosine 5'-triphosphate5 mM MnCl2 (5 mM Mn2+); baculovirus/Sf9 | — | 0.0301 | — | pH 7.5 | Open record: COT kinase (cancer osaka thyroid, MAP3K), adenosine 5'-triphosphate |
| COT kinase (cancer osaka thyroid, MAP3K) | Homo sapiens | adenosine 5'-triphosphate10 mM MgCl2 (10 mM Mg2+); baculovirus/Sf9 | — | 0.31 | — | pH 7.5 | Open record: COT kinase (cancer osaka thyroid, MAP3K), adenosine 5'-triphosphate |
| COT kinase (cancer osaka thyroid, MAP3K) | Homo sapiens | adenosine 5'-triphosphate5 mM MnCl2 (5 mM Mn2+); baculovirus/Sf9 | — | 0.0297 | — | pH 7.5 | Open record: COT kinase (cancer osaka thyroid, MAP3K), adenosine 5'-triphosphate |
| COT kinase (cancer osaka thyroid, MAP3K) | Homo sapiens | adenosine 5'-triphosphate10 mM MgCl2 (10 mM Mg2+); baculovirus/Sf9 | — | 0.394 | — | pH 7.5 | Open record: COT kinase (cancer osaka thyroid, MAP3K), adenosine 5'-triphosphate |
| COT kinase (cancer osaka thyroid, MAP3K) | Homo sapiens | MAP/Erk kinase (unactive GST-MEK protein, MAP2K)5 mM MnCl2 (5 mM Mn2+) | 0.257 | 1.9 × 10⁻⁴ | 1.35 × 10³ | pH 7.5 | Open record: COT kinase (cancer osaka thyroid, MAP3K), MAP/Erk kinase (unactive GST-MEK protein, MAP2K) |
| COT kinase (cancer osaka thyroid, MAP3K) | Homo sapiens | MAP/Erk kinase (unactive GST-MEK protein, MAP2K)10 mM MgCl2 (10 mM Mg2+) | 0.245 | 3.6 × 10⁻⁴ | 680 | pH 7.5 | Open record: COT kinase (cancer osaka thyroid, MAP3K), MAP/Erk kinase (unactive GST-MEK protein, MAP2K) |
| COT kinase (cancer osaka thyroid, MAP3K) | Homo sapiens | MAP/Erk kinase (unactive GST-MEK protein, MAP2K)5 mM MnCl2 (5 mM Mn2+); baculovirus/Sf9 | 0.0325 | 3 × 10⁻⁴ | 108 | pH 7.5 | Open record: COT kinase (cancer osaka thyroid, MAP3K), MAP/Erk kinase (unactive GST-MEK protein, MAP2K) |
| COT kinase (cancer osaka thyroid, MAP3K) | Homo sapiens | MAP/Erk kinase (unactive GST-MEK protein, MAP2K)10 mM MgCl2 (10 mM Mg2+); baculovirus/Sf9 | 0.0328 | 3 × 10⁻⁴ | 110 | pH 7.5 | Open record: COT kinase (cancer osaka thyroid, MAP3K), MAP/Erk kinase (unactive GST-MEK protein, MAP2K) |
| COT kinase (cancer osaka thyroid, MAP3K) | Homo sapiens | MAP/Erk kinase (unactive GST-MEK protein, MAP2K)5 mM MnCl2 (5 mM Mn2+); baculovirus/Sf9 | 0.0055 | 1.6 × 10⁻⁴ | 35 | pH 7.5 | Open record: COT kinase (cancer osaka thyroid, MAP3K), MAP/Erk kinase (unactive GST-MEK protein, MAP2K) |
| COT kinase (cancer osaka thyroid, MAP3K) | Homo sapiens | MAP/Erk kinase (unactive GST-MEK protein, MAP2K)10 mM MgCl2 (10 mM Mg2+); baculovirus/Sf9 | 0.005 | 3.1 × 10⁻⁴ | 17 | pH 7.5 | Open record: COT kinase (cancer osaka thyroid, MAP3K), MAP/Erk kinase (unactive GST-MEK protein, MAP2K) |