Values CatLog read from this paper
Functional characterization of four allelic variants of human cytochrome P450 1A2
PMID 14725854doi:10.1016/j.abb.2003.11.019Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 24 records (48 values) from this paper: cytochrome P450 1A2 from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 24 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| cytochrome P450 1A2 | Homo sapiens | 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine | 0.18 | 0.071 | 2.6 calc. | pH 7.4, 37 °C | Open record: cytochrome P450 1A2, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine |
| cytochrome P450 1A2 | Homo sapiens | 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline | 0.09 | 0.027 | 3.3 calc. | pH 7.4, 37 °C | Open record: cytochrome P450 1A2, 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline |
| cytochrome P450 1A2 | Homo sapiens | 2-amino-3-methylimidazo[4,5-f]quinoline | 0.097 | 0.021 | 4.6 calc. | pH 7.4, 37 °C | Open record: cytochrome P450 1A2, 2-amino-3-methylimidazo[4,5-f]quinoline |
| cytochrome P450 1A2 | Homo sapiens | 2-amino-6-methyldipyrido[1,2-a :3^′,2^′-d]imidazole | 0.083 | 0.004 | 21 calc. | pH 7.4, 37 °C | Open record: cytochrome P450 1A2, 2-amino-6-methyldipyrido[1,2-a :3^′,2^′-d]imidazole |
| cytochrome P450 1A2 | Homo sapiens | MeIQ | 0.05 | 0.026 | 1.9 calc. | pH 7.4, 37 °C | Open record: cytochrome P450 1A2, MeIQ |
| cytochrome P450 1A2 | Homo sapiens | phenacetin | 0.025 | 0.025 | 1.0 calc. | pH 7.4 | Open record: cytochrome P450 1A2, phenacetin |
| cytochrome P450 1A2variant C406Y | Homo sapiens | 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine | 0.43 | 0.066 | 6.6 calc. | pH 7.4, 37 °C | Open record: cytochrome P450 1A2 variant C406Y, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine |
| cytochrome P450 1A2variant C406Y | Homo sapiens | 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline | 0.127 | 0.02 | 6.3 calc. | pH 7.4, 37 °C | Open record: cytochrome P450 1A2 variant C406Y, 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline |
| cytochrome P450 1A2variant C406Y | Homo sapiens | 2-amino-3-methylimidazo[4,5-f]quinoline | 0.138 | 0.022 | 6.3 calc. | pH 7.4, 37 °C | Open record: cytochrome P450 1A2 variant C406Y, 2-amino-3-methylimidazo[4,5-f]quinoline |
| cytochrome P450 1A2variant C406Y | Homo sapiens | 2-amino-6-methyldipyrido[1,2-a :3^′,2^′-d]imidazole | 0.22 | 0.011 | 20 calc. | pH 7.4, 37 °C | Open record: cytochrome P450 1A2 variant C406Y, 2-amino-6-methyldipyrido[1,2-a :3^′,2^′-d]imidazole |
| cytochrome P450 1A2variant C406Y | Homo sapiens | MeIQ | 0.075 | 0.014 | 5.4 calc. | pH 7.4, 37 °C | Open record: cytochrome P450 1A2 variant C406Y, MeIQ |
| cytochrome P450 1A2variant C406Y | Homo sapiens | phenacetin | 0.02 | 0.062 | 0.32 calc. | pH 7.4 | Open record: cytochrome P450 1A2 variant C406Y, phenacetin |
| cytochrome P450 1A2variant D348N | Homo sapiens | 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine | 0.48 | 0.062 | 7.8 calc. | pH 7.4, 37 °C | Open record: cytochrome P450 1A2 variant D348N, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine |
| cytochrome P450 1A2variant D348N | Homo sapiens | 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline | 0.15 | 0.033 | 4.5 calc. | pH 7.4, 37 °C | Open record: cytochrome P450 1A2 variant D348N, 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline |
| cytochrome P450 1A2variant D348N | Homo sapiens | 2-amino-3-methylimidazo[4,5-f]quinoline | 0.193 | 0.027 | 7.2 calc. | pH 7.4, 37 °C | Open record: cytochrome P450 1A2 variant D348N, 2-amino-3-methylimidazo[4,5-f]quinoline |
| cytochrome P450 1A2variant D348N | Homo sapiens | 2-amino-6-methyldipyrido[1,2-a :3^′,2^′-d]imidazole | 0.22 | 0.013 | 17 calc. | pH 7.4, 37 °C | Open record: cytochrome P450 1A2 variant D348N, 2-amino-6-methyldipyrido[1,2-a :3^′,2^′-d]imidazole |
| cytochrome P450 1A2variant D348N | Homo sapiens | MeIQ | 0.068 | 0.017 | 4.0 calc. | pH 7.4, 37 °C | Open record: cytochrome P450 1A2 variant D348N, MeIQ |
| cytochrome P450 1A2variant D348N | Homo sapiens | phenacetin | 0.015 | 0.018 | 0.83 calc. | pH 7.4 | Open record: cytochrome P450 1A2 variant D348N, phenacetin |
| cytochrome P450 1A2variant I386F | Homo sapiens | 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine | 0.33 | 0.341 | 0.98 calc. | pH 7.4, 37 °C | Open record: cytochrome P450 1A2 variant I386F, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine |
| cytochrome P450 1A2variant I386F | Homo sapiens | 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline | 0.3 | 0.046 | 6.5 calc. | pH 7.4, 37 °C | Open record: cytochrome P450 1A2 variant I386F, 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline |
| cytochrome P450 1A2variant I386F | Homo sapiens | 2-amino-3-methylimidazo[4,5-f]quinoline | 0.048 | 0.037 | 1.3 calc. | pH 7.4, 37 °C | Open record: cytochrome P450 1A2 variant I386F, 2-amino-3-methylimidazo[4,5-f]quinoline |
| cytochrome P450 1A2variant I386F | Homo sapiens | 2-amino-6-methyldipyrido[1,2-a :3^′,2^′-d]imidazole | 0.23 | 0.016 | 15 calc. | pH 7.4, 37 °C | Open record: cytochrome P450 1A2 variant I386F, 2-amino-6-methyldipyrido[1,2-a :3^′,2^′-d]imidazole |
| cytochrome P450 1A2variant I386F | Homo sapiens | MeIQ | 0.013 | 0.0045 | 3.0 calc. | pH 7.4, 37 °C | Open record: cytochrome P450 1A2 variant I386F, MeIQ |
| cytochrome P450 1A2variant I386F | Homo sapiens | phenacetin | 0.043 | 0.32 | 0.14 calc. | pH 7.4 | Open record: cytochrome P450 1A2 variant I386F, phenacetin |