Values CatLog read from this paper

Critical Sites of DNA Backbone Integrity for Damaged Base Removal by Formamidopyrimidine-DNA Glycosylase

PMID 31120733doi:10.1021/acs.biochem.9b00134Open in Browse

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CatLog read 22 records (66 values) from this paper: formamidopyrimidine-DNA glycosylase (Fpg, MutM) from Escherichia coli.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.2.2.23

Records read from this paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Open record
formamidopyrimidine-DNA glycosylase (Fpg, MutM)	Escherichia coli	8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the A(+2)−p(+2) phosphoester link of the complementary (nondamaged) strand	0.025	2.1 × 10⁻⁵	1.18 × 10³	pH 7.5, 30 °C	Open record: formamidopyrimidine-DNA glycosylase (Fpg, MutM), 8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the A(+2)−p(+2) phosphoester link of the complementary (nondamaged) strand
formamidopyrimidine-DNA glycosylase (Fpg, MutM)	Escherichia coli	8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the A(−2)−p(−2) phosphoester link of the complementary (nondamaged) strand	0.0138	2.7 × 10⁻⁵	520	pH 7.5, 30 °C	Open record: formamidopyrimidine-DNA glycosylase (Fpg, MutM), 8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the A(−2)−p(−2) phosphoester link of the complementary (nondamaged) strand
formamidopyrimidine-DNA glycosylase (Fpg, MutM)	Escherichia coli	8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the C(0)−p(0) phosphoester link of the complementary (nondamaged) strand	0.0108	3 × 10⁻⁵	370	pH 7.5, 30 °C	Open record: formamidopyrimidine-DNA glycosylase (Fpg, MutM), 8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the C(0)−p(0) phosphoester link of the complementary (nondamaged) strand
formamidopyrimidine-DNA glycosylase (Fpg, MutM)	Escherichia coli	8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the C+1−p0 phosphoester link of the oxoG-containing (damaged) strand	0.045	1.4 × 10⁻⁵	3.2 × 10³	pH 7.5, 30 °C	Open record: formamidopyrimidine-DNA glycosylase (Fpg, MutM), 8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the C+1−p0 phosphoester link of the oxoG-containing (damaged) strand
formamidopyrimidine-DNA glycosylase (Fpg, MutM)	Escherichia coli	8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the C−1−p−2 phosphoester link of the oxoG-containing (damaged) strand	0.0037	8.2 × 10⁻⁶	450	pH 7.5, 30 °C	Open record: formamidopyrimidine-DNA glycosylase (Fpg, MutM), 8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the C−1−p−2 phosphoester link of the oxoG-containing (damaged) strand
formamidopyrimidine-DNA glycosylase (Fpg, MutM)	Escherichia coli	8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the G(+1)−p(+1) phosphoester link of the complementary (nondamaged) strand	0.014	2.7 × 10⁻⁵	520	pH 7.5, 30 °C	Open record: formamidopyrimidine-DNA glycosylase (Fpg, MutM), 8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the G(+1)−p(+1) phosphoester link of the complementary (nondamaged) strand
formamidopyrimidine-DNA glycosylase (Fpg, MutM)	Escherichia coli	8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the G(−1)−p(−1) phosphoester link of the complementary (nondamaged) strand	0.028	2.8 × 10⁻⁵	1.02 × 10³	pH 7.5, 30 °C	Open record: formamidopyrimidine-DNA glycosylase (Fpg, MutM), 8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the G(−1)−p(−1) phosphoester link of the complementary (nondamaged) strand
formamidopyrimidine-DNA glycosylase (Fpg, MutM)	Escherichia coli	8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the G(−3)−p(−3) phosphoester link of the complementary (nondamaged) strand	0.018	1.7 × 10⁻⁵	1.08 × 10³	pH 7.5, 30 °C	Open record: formamidopyrimidine-DNA glycosylase (Fpg, MutM), 8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the G(−3)−p(−3) phosphoester link of the complementary (nondamaged) strand
formamidopyrimidine-DNA glycosylase (Fpg, MutM)	Escherichia coli	8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the p(+1)−A(+2) phosphoester link of the complementary (nondamaged) strand	0.0113	1.4 × 10⁻⁵	820	pH 7.5, 30 °C	Open record: formamidopyrimidine-DNA glycosylase (Fpg, MutM), 8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the p(+1)−A(+2) phosphoester link of the complementary (nondamaged) strand
formamidopyrimidine-DNA glycosylase (Fpg, MutM)	Escherichia coli	8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the p(+2)−A(+3) phosphoester link of the complementary (nondamaged) strand	0.022	1.8 × 10⁻⁵	1.2 × 10³	pH 7.5, 30 °C	Open record: formamidopyrimidine-DNA glycosylase (Fpg, MutM), 8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the p(+2)−A(+3) phosphoester link of the complementary (nondamaged) strand
formamidopyrimidine-DNA glycosylase (Fpg, MutM)	Escherichia coli	8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the p(0)−G(+1) phosphoester link of the complementary (nondamaged) strand	0.017	3.6 × 10⁻⁵	470	pH 7.5, 30 °C	Open record: formamidopyrimidine-DNA glycosylase (Fpg, MutM), 8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the p(0)−G(+1) phosphoester link of the complementary (nondamaged) strand
formamidopyrimidine-DNA glycosylase (Fpg, MutM)	Escherichia coli	8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the p(−1)−C(0) phosphoester link of the complementary (nondamaged) strand	0.0133	2.8 × 10⁻⁵	480	pH 7.5, 30 °C	Open record: formamidopyrimidine-DNA glycosylase (Fpg, MutM), 8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the p(−1)−C(0) phosphoester link of the complementary (nondamaged) strand
formamidopyrimidine-DNA glycosylase (Fpg, MutM)	Escherichia coli	8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the p(−2)−G(−1) phosphoester link of the complementary (nondamaged) strand	0.01	1.2 × 10⁻⁵	830	pH 7.5, 30 °C	Open record: formamidopyrimidine-DNA glycosylase (Fpg, MutM), 8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the p(−2)−G(−1) phosphoester link of the complementary (nondamaged) strand
formamidopyrimidine-DNA glycosylase (Fpg, MutM)	Escherichia coli	8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the p(−3)−A(−2) phosphoester link of the complementary (nondamaged) strand	0.015	2.3 × 10⁻⁵	650	pH 7.5, 30 °C	Open record: formamidopyrimidine-DNA glycosylase (Fpg, MutM), 8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the p(−3)−A(−2) phosphoester link of the complementary (nondamaged) strand
formamidopyrimidine-DNA glycosylase (Fpg, MutM)	Escherichia coli	8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the p+1−C+1 phosphoester link of the oxoG-containing (damaged) strand	0.047	2.3 × 10⁻⁵	2 × 10³	pH 7.5, 30 °C	Open record: formamidopyrimidine-DNA glycosylase (Fpg, MutM), 8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the p+1−C+1 phosphoester link of the oxoG-containing (damaged) strand
formamidopyrimidine-DNA glycosylase (Fpg, MutM)	Escherichia coli	8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the p+2−T+2 phosphoester link of the oxoG-containing (damaged) strand	0.023	7.5 × 10⁻⁶	3.2 × 10³	pH 7.5, 30 °C	Open record: formamidopyrimidine-DNA glycosylase (Fpg, MutM), 8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the p+2−T+2 phosphoester link of the oxoG-containing (damaged) strand
formamidopyrimidine-DNA glycosylase (Fpg, MutM)	Escherichia coli	8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the p−3−C−3 phosphoester link of the oxoG-containing (damaged) strand	0.0138	1.2 × 10⁻⁵	1.15 × 10³	pH 7.5, 30 °C	Open record: formamidopyrimidine-DNA glycosylase (Fpg, MutM), 8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the p−3−C−3 phosphoester link of the oxoG-containing (damaged) strand
formamidopyrimidine-DNA glycosylase (Fpg, MutM)	Escherichia coli	8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the T+2−p+1 phosphoester link of the oxoG-containing (damaged) strand	0.02	4.8 × 10⁻⁵	420	pH 7.5, 30 °C	Open record: formamidopyrimidine-DNA glycosylase (Fpg, MutM), 8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the T+2−p+1 phosphoester link of the oxoG-containing (damaged) strand
formamidopyrimidine-DNA glycosylase (Fpg, MutM)	Escherichia coli	8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the T+3−p+2 phosphoester link of the oxoG-containing (damaged) strand	0.022	7 × 10⁻⁶	3.2 × 10³	pH 7.5, 30 °C	Open record: formamidopyrimidine-DNA glycosylase (Fpg, MutM), 8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the T+3−p+2 phosphoester link of the oxoG-containing (damaged) strand
formamidopyrimidine-DNA glycosylase (Fpg, MutM)	Escherichia coli	8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the T−2−p−3 phosphoester link of the oxoG-containing (damaged) strand	0.0147	1.1 × 10⁻⁵	1.33 × 10³	pH 7.5, 30 °C	Open record: formamidopyrimidine-DNA glycosylase (Fpg, MutM), 8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept) disrupting the T−2−p−3 phosphoester link of the oxoG-containing (damaged) strand
formamidopyrimidine-DNA glycosylase (Fpg, MutM)	Escherichia coli	8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept; 3′-terminal 2′,3′-dideoxynucleotide at the break) disrupting the ddT−2−p−3 phosphoester link of the oxoG-containing (damaged) strand	0.0092	4 × 10⁻⁶	2.3 × 10³	pH 7.5, 30 °C	Open record: formamidopyrimidine-DNA glycosylase (Fpg, MutM), 8-oxoguanine (oxoG):C DNA duplex with a single-strand break (all phosphates kept; 3′-terminal 2′,3′-dideoxynucleotide at the break) disrupting the ddT−2−p−3 phosphoester link of the oxoG-containing (damaged) strand
formamidopyrimidine-DNA glycosylase (Fpg, MutM)	Escherichia coli	8-oxoguanine (oxoG):C-containing DNA duplex without a break (40-mer)	0.0055	9.7 × 10⁻⁶	570	pH 7.5, 30 °C	Open record: formamidopyrimidine-DNA glycosylase (Fpg, MutM), 8-oxoguanine (oxoG):C-containing DNA duplex without a break (40-mer)