Values CatLog read from this paper
Characterization of two novel aldo-keto reductases from Arabidopsis: expression patterns, broad substrate specificity, and an open active-site structure suggest a role in toxicant metabolism…
PMID 19616008doi:10.1016/j.jmb.2009.07.023Open in Browse
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CatLog read 39 records (109 values) from this paper: aldo-keto reductase AKR4C9, aldo-keto reductase AKR4C8 from Arabidopsis thaliana.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| aldo-keto reductase AKR4C8 | Arabidopsis thaliana | 17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)reduction; 150 µM NADPH; reduction at C3; cosubstrate NADPH | 0.13 | 0.147 | 0.97 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C8, 17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone) |
| aldo-keto reductase AKR4C8 | Arabidopsis thaliana | 17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)oxidation; 1 mM NADP+; oxidation at C17; cosubstrate NADP+ | 0.7 | 0.064 | 10.9 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C8, 17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone) |
| aldo-keto reductase AKR4C8 | Arabidopsis thaliana | 3α-hydroxy-5α-androstan-17-one (androsterone) | 0.37 | 0.05 | 4.15 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C8, 3α-hydroxy-5α-androstan-17-one (androsterone) |
| aldo-keto reductase AKR4C8 | Arabidopsis thaliana | 3β-hydroxy-5α-androstan-17-one (epiandrosterone) | 0.32 | 0.055 | 5.58 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C8, 3β-hydroxy-5α-androstan-17-one (epiandrosterone) |
| aldo-keto reductase AKR4C8 | Arabidopsis thaliana | 4-hydroxy-2-nonenal | — | — | 0.0675 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C8, 4-hydroxy-2-nonenal |
| aldo-keto reductase AKR4C8 | Arabidopsis thaliana | 5α-androstane-3,17-dione | 0.42 | 0.053 | 7.45 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C8, 5α-androstane-3,17-dione |
| aldo-keto reductase AKR4C8 | Arabidopsis thaliana | 5α-androstane-3α,17β-diol | 0.107 | 0.019 | 5.52 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C8, 5α-androstane-3α,17β-diol |
| aldo-keto reductase AKR4C8 | Arabidopsis thaliana | Glyceraldehyde | 1.12 | 22.4 | 0.05 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C8, Glyceraldehyde |
| aldo-keto reductase AKR4C8 | Arabidopsis thaliana | Glyoxal | 2.07 | 1.6 | 1.3 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C8, Glyoxal |
| aldo-keto reductase AKR4C8 | Arabidopsis thaliana | Isatin | 3.03 | 0.035 | 85.97 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C8, Isatin |
| aldo-keto reductase AKR4C8 | Arabidopsis thaliana | Methylglyoxal | 3.2 | 3.3 | 0.97 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C8, Methylglyoxal |
| aldo-keto reductase AKR4C8 | Arabidopsis thaliana | phenanthrene-9,10-dione | 6.35 | 0.0044 | 1442 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C8, phenanthrene-9,10-dione |
| aldo-keto reductase AKR4C9 | Arabidopsis thaliana | (E)-hex-2-enal | 3.53 | 5.49 | 0.65 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C9, (E)-hex-2-enal |
| aldo-keto reductase AKR4C9 | Arabidopsis thaliana | 17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)reduction; 150 µM NADPH; reduction at C3; cosubstrate NADPH | 0.0025 | 0.06 | 0.0427 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C9, 17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone) |
| aldo-keto reductase AKR4C9 | Arabidopsis thaliana | 17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)oxidation; 1 mM NADP+; oxidation at C17; cosubstrate NADP+ | 0.0022 | 0.0278 | 0.0882 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C9, 17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone) |
| aldo-keto reductase AKR4C9 | Arabidopsis thaliana | 2-Hydroxybenzaldehyde | — | — | 2.58 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C9, 2-Hydroxybenzaldehyde |
| aldo-keto reductase AKR4C9 | Arabidopsis thaliana | 3-Fluorobenzaldehyde | 5.73 | 0.102 | 56.2 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C9, 3-Fluorobenzaldehyde |
| aldo-keto reductase AKR4C9 | Arabidopsis thaliana | 3-Hydroxybenzaldehyde | 1.1 | 0.261 | 4.22 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C9, 3-Hydroxybenzaldehyde |
| aldo-keto reductase AKR4C9 | Arabidopsis thaliana | 3α-hydroxy-5α-androstan-17-one (androsterone) | 0.006 | 0.262 | 0.0223 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C9, 3α-hydroxy-5α-androstan-17-one (androsterone) |
| aldo-keto reductase AKR4C9 | Arabidopsis thaliana | 3β-hydroxy-5α-androstan-17-one (epiandrosterone) | 0.0017 | 0.226 | 0.007 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C9, 3β-hydroxy-5α-androstan-17-one (epiandrosterone) |
| aldo-keto reductase AKR4C9 | Arabidopsis thaliana | 4-hydroxy-2-nonenal | 3.6 | 4 | 0.9 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C9, 4-hydroxy-2-nonenal |
| aldo-keto reductase AKR4C9 | Arabidopsis thaliana | 5α-androstane-3,17-dione | 0.0077 | 0.051 | 0.1495 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C9, 5α-androstane-3,17-dione |
| aldo-keto reductase AKR4C9 | Arabidopsis thaliana | 5α-androstane-3α,17β-diol | 0.001 | 0.0236 | 0.0418 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C9, 5α-androstane-3α,17β-diol |
| aldo-keto reductase AKR4C9 | Arabidopsis thaliana | Arabinose | 5.85 | 240 | 0.0243 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C9, Arabinose |
| aldo-keto reductase AKR4C9 | Arabidopsis thaliana | Benzaldehyde | 6.25 | 1.445 | 4.3 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C9, Benzaldehyde |
| aldo-keto reductase AKR4C9 | Arabidopsis thaliana | Cinnamylaldehyde | 1.37 | 0.27 | 5.08 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C9, Cinnamylaldehyde |
| aldo-keto reductase AKR4C9 | Arabidopsis thaliana | Decanal | — | — | 50.37 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C9, Decanal |
| aldo-keto reductase AKR4C9 | Arabidopsis thaliana | Erythrose | 3.67 | 2.8 | 1.32 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C9, Erythrose |
| aldo-keto reductase AKR4C9 | Arabidopsis thaliana | Galactose | 0.5 | 121 | 0.0042 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C9, Galactose |
| aldo-keto reductase AKR4C9 | Arabidopsis thaliana | Glucose | 1.47 | 760 | 0.002 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C9, Glucose |
| aldo-keto reductase AKR4C9 | Arabidopsis thaliana | Glyceraldehyde | 9.67 | 2.2 | 4.4 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C9, Glyceraldehyde |
| aldo-keto reductase AKR4C9 | Arabidopsis thaliana | Glyoxal | 9.68 | 10.2 | 0.95 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C9, Glyoxal |
| aldo-keto reductase AKR4C9 | Arabidopsis thaliana | Isatin | — | — | 1.52 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C9, Isatin |
| aldo-keto reductase AKR4C9 | Arabidopsis thaliana | Isopropylbenzaldehyde | 1.9 | 0.082 | 23.2 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C9, Isopropylbenzaldehyde |
| aldo-keto reductase AKR4C9 | Arabidopsis thaliana | Malondialdehyde | 0.25 | 51 | 0.0048 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C9, Malondialdehyde |
| aldo-keto reductase AKR4C9 | Arabidopsis thaliana | Methylglyoxal | 15.05 | 0.46 | 32.72 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C9, Methylglyoxal |
| aldo-keto reductase AKR4C9 | Arabidopsis thaliana | phenanthrene-9,10-dione | 9.97 | 0.0044 | 2269 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C9, phenanthrene-9,10-dione |
| aldo-keto reductase AKR4C9 | Arabidopsis thaliana | pregn-4-ene-3,20-dione | 0.0018 | 0.0085 | 0.238 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C9, pregn-4-ene-3,20-dione |
| aldo-keto reductase AKR4C9 | Arabidopsis thaliana | Xylose | 4.45 | 238 | 0.0187 | pH 7, 25 °C | Open record: aldo-keto reductase AKR4C9, Xylose |