Values CatLog read from this paper
Molecular basis for vancomycin resistance in Enterococcus faecium BM4147: biosynthesis of a depsipeptide peptidoglycan precursor by vancomycin resistance proteins VanH and VanA
PMID 1931965doi:10.1021/bi00107a007Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 39 records (79 values) from this paper: VanA, D-lactate dehydrogenase, VanH and 1 more from Enterococcus faecium, Escherichia coli, Lactobacillus leichmanii and 1 more.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
EC 1.1.1.28, EC 1.1.1.272, EC 1.1.1.345, EC 6.1.2.1, EC 6.3.2.10
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| D-Ala-D-Ala adding enzyme | Escherichia coli | D-alanyl-D-2-hydroxybutyrate | 9.2 | 2.6 | 3.5 | pH 8.6, 37 °C | Open record: D-Ala-D-Ala adding enzyme, D-alanyl-D-2-hydroxybutyrate |
| D-Ala-D-Ala adding enzyme | Escherichia coli | D-alanyl-D-alanine | 18 | 0.054 | 330 | pH 8.6, 37 °C | Open record: D-Ala-D-Ala adding enzyme, D-alanyl-D-alanine |
| D-Ala-D-Ala adding enzyme | Escherichia coli | D-alanyl-D-lactate | 13.8 | 0.095 | 150 | pH 8.6, 37 °C | Open record: D-Ala-D-Ala adding enzyme, D-alanyl-D-lactate |
| D-Ala-D-Ala adding enzyme | Escherichia coli | D-alanyl-D-methionine | 0.57 | 21 | 0.027 | pH 8.6, 37 °C | Open record: D-Ala-D-Ala adding enzyme, D-alanyl-D-methionine |
| D-Ala-D-Ala adding enzyme | Escherichia coli | D-alanyl-D-phenylalanine | 0.92 | 32 | 0.029 | pH 8.6, 37 °C | Open record: D-Ala-D-Ala adding enzyme, D-alanyl-D-phenylalanine |
| D-lactate dehydrogenase | Lactobacillus leichmanii | NADH | — | 0.01 | — | pH 5.6 | Open record: D-lactate dehydrogenase, NADH |
| D-lactate dehydrogenase | Lactobacillus leichmanii | NADPH | — | 0.19 | — | pH 5.6 | Open record: D-lactate dehydrogenase, NADPH |
| D-lactate dehydrogenase | Lactobacillus leichmanii | phenylpyruvate | 55 | 11.7 | 2.9 | pH 5.6 | Open record: D-lactate dehydrogenase, phenylpyruvate |
| D-lactate dehydrogenase | Lactobacillus leichmanii | pyruvate | 290 | 0.14 | 1.3 × 10³ | pH 5.6 | Open record: D-lactate dehydrogenase, pyruvate |
| D-lactate dehydrogenase | Lactobacillus leichmanii | α-ketobutyrate | 252 | 34 | 4.6 | pH 5.6 | Open record: D-lactate dehydrogenase, α-ketobutyrate |
| D-lactate dehydrogenase | Leuconostoc mesenteroides | NADH | — | 0.008 | — | pH 5.6 | Open record: D-lactate dehydrogenase, NADH |
| D-lactate dehydrogenase | Leuconostoc mesenteroides | NADPH | — | 0.096 | — | pH 5.6 | Open record: D-lactate dehydrogenase, NADPH |
| D-lactate dehydrogenase | Leuconostoc mesenteroides | phenylpyruvate | 1.15 × 10³ | 6.7 | 100 | pH 5.6 | Open record: D-lactate dehydrogenase, phenylpyruvate |
| D-lactate dehydrogenase | Leuconostoc mesenteroides | pyruvate | 2.68 × 10³ | 0.075 | 2.2 × 10⁴ | pH 5.6 | Open record: D-lactate dehydrogenase, pyruvate |
| D-lactate dehydrogenase | Leuconostoc mesenteroides | α-ketobutyrate | 1.9 × 10³ | 12.5 | 92 | pH 5.6 | Open record: D-lactate dehydrogenase, α-ketobutyrate |
| VanA | Enterococcus faecium | D-2-hydroxybutyrate | — | 0.6 | — | pH 8.6, 25 °C | Open record: VanA, D-2-hydroxybutyrate |
| VanA | Enterococcus faecium | D-2-hydroxybutyrate | 1.8 | — | 3 | pH 8.6 | Open record: VanA, D-2-hydroxybutyrate |
| VanA | Enterococcus faecium | D-2-hydroxycaproate | — | 11 | — | pH 8.6, 25 °C | Open record: VanA, D-2-hydroxycaproate |
| VanA | Enterococcus faecium | D-2-hydroxycaproate | 1.1 | — | 0.1 | pH 8.6 | Open record: VanA, D-2-hydroxycaproate |
| VanA | Enterococcus faecium | D-2-hydroxyvalerate | — | 3.2 | — | pH 8.6, 25 °C | Open record: VanA, D-2-hydroxyvalerate |
| VanA | Enterococcus faecium | D-2-hydroxyvalerate | 2.6 | — | 0.81 | pH 8.6 | Open record: VanA, D-2-hydroxyvalerate |
| VanA | Enterococcus faecium | D-alaninecosubstrate D-alanine | — | 3.8 | — | pH 8.6, 25 °C | Open record: VanA, D-alanine |
| VanA | Enterococcus faecium | D-alaninecosubstrate D-alanine | — | 38 | — | pH 8.6, 25 °C | Open record: VanA, D-alanine |
| VanA | Enterococcus faecium | D-alanine | 4.92 | — | 0.13 | pH 8.6 | Open record: VanA, D-alanine |
| VanA | Enterococcus faecium | D-alaninecosubstrate D-lactate | — | 3.2 | — | pH 8.6, 25 °C | Open record: VanA, D-alanine |
| VanA | Enterococcus faecium | D-alaninecosubstrate D-2-hydroxybutyrate | — | 4.1 | — | pH 8.6, 25 °C | Open record: VanA, D-alanine |
| VanA | Enterococcus faecium | D-aminobutyrate | — | 0.77 | — | pH 8.6, 25 °C | Open record: VanA, D-aminobutyrate |
| VanA | Enterococcus faecium | D-lactate | — | 7.1 | — | pH 8.6, 25 °C | Open record: VanA, D-lactate |
| VanA | Enterococcus faecium | D-lactate | 1.57 | — | 0.22 | pH 8.6 | Open record: VanA, D-lactate |
| VanA | Enterococcus faecium | D-phenyllactate | — | 60 | — | pH 8.6, 25 °C | Open record: VanA, D-phenyllactate |
| VanA | Enterococcus faecium | D-phenyllactate | 1.25 | — | 0.02 | pH 8.6 | Open record: VanA, D-phenyllactate |
| VanH | Enterococcus faecium | NADH | — | 0.021 | — | pH 5.6 | Open record: VanH, NADH |
| VanH | Enterococcus faecium | NADPH | — | 0.002 | — | pH 5.6 | Open record: VanH, NADPH |
| VanH | Enterococcus faecium | pyruvate | 40 | 1.45 | 28 | pH 5.6 | Open record: VanH, pyruvate |
| VanH | Enterococcus faecium | α-ketobutyrate | 35 | 2.6 | 14 | pH 5.6 | Open record: VanH, α-ketobutyrate |
| VanH | Enterococcus faecium | α-ketocaproate | 2.4 | 20 | 0.12 | pH 5.6 | Open record: VanH, α-ketocaproate |
| VanH | Enterococcus faecium | α-ketoisocaproate | 5.2 | 31 | 0.168 | pH 5.6 | Open record: VanH, α-ketoisocaproate |
| VanH | Enterococcus faecium | α-ketoisovalerate | 5.2 | 150 | 0.035 | pH 5.6 | Open record: VanH, α-ketoisovalerate |
| VanH | Enterococcus faecium | α-ketovalerate | 35 | 40 | 0.88 | pH 5.6 | Open record: VanH, α-ketovalerate |