EC 1.1.1.345: D-2-hydroxyacid dehydrogenase (NAD+)
OxidoreductasesOpen in Browse
CatLog read 25 records for EC 1.1.1.345 from 2 papers, for 2 organisms. Names in these papers: R-2-hydroxyisocaproate dehydrogenase (R-HicDH), VanH.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 16 records for EC 1.1.1.345 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.1.1.345 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| doi:10.1016/0141-0229(92)90022-g | Lactobacillus casei | 17 |
| Molecular basis for vancomycin resistance in Enterococcus faecium BM4147: biosynthesis of a depsipeptide peptidoglycan precursor by vancomycin resistance proteins VanH and VanA | Enterococcus faecium | 8 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| R-2-hydroxyisocaproate dehydrogenase (R-HicDH) | Lactobacillus casei | (2R)-2-hydroxy-4-methylpentanoate | 43 | 2.3 | 18 | pH 7 | doi:10.1016/0141-0229(92)90022-g | Open record: R-2-hydroxyisocaproate dehydrogenase (R-HicDH), (2R)-2-hydroxy-4-methylpentanoate |
| R-2-hydroxyisocaproate dehydrogenase (R-HicDH) | Lactobacillus casei | 2-hydroxy-3-(1H-indol-3-yl)propanoate | 43 | 3 | 14 | pH 7 | doi:10.1016/0141-0229(92)90022-g | Open record: R-2-hydroxyisocaproate dehydrogenase (R-HicDH), 2-hydroxy-3-(1H-indol-3-yl)propanoate |
| R-2-hydroxyisocaproate dehydrogenase (R-HicDH) | Lactobacillus casei | 2-hydroxy-4-(methylsulfanyl)butanoate | 6 | 11 | 0.55 | pH 7 | doi:10.1016/0141-0229(92)90022-g | Open record: R-2-hydroxyisocaproate dehydrogenase (R-HicDH), 2-hydroxy-4-(methylsulfanyl)butanoate |
| R-2-hydroxyisocaproate dehydrogenase (R-HicDH) | Lactobacillus casei | 2-hydroxy-4-methylpentanoate | 43 | 3.9 | 11 | pH 7 | doi:10.1016/0141-0229(92)90022-g | Open record: R-2-hydroxyisocaproate dehydrogenase (R-HicDH), 2-hydroxy-4-methylpentanoate |
| R-2-hydroxyisocaproate dehydrogenase (R-HicDH) | Lactobacillus casei | 2-hydroxyoctanoate | 25 | 1.6 | 16 calc. | pH 7 | doi:10.1016/0141-0229(92)90022-g | Open record: R-2-hydroxyisocaproate dehydrogenase (R-HicDH), 2-hydroxyoctanoate |
| R-2-hydroxyisocaproate dehydrogenase (R-HicDH) | Lactobacillus casei | 2-oxo-3-phenylpropanoate | 968 | 0.2 | 4.8 × 10³ | pH 7 | doi:10.1016/0141-0229(92)90022-g | Open record: R-2-hydroxyisocaproate dehydrogenase (R-HicDH), 2-oxo-3-phenylpropanoate |
| R-2-hydroxyisocaproate dehydrogenase (R-HicDH) | Lactobacillus casei | 2-oxobutanoate | 171 | 2.1 | 81 | pH 7 | doi:10.1016/0141-0229(92)90022-g | Open record: R-2-hydroxyisocaproate dehydrogenase (R-HicDH), 2-oxobutanoate |
| R-2-hydroxyisocaproate dehydrogenase (R-HicDH) | Lactobacillus casei | 2-oxohexanoate | 139 | 0.13 | 1.1 × 10³ calc. | pH 7 | doi:10.1016/0141-0229(92)90022-g | Open record: R-2-hydroxyisocaproate dehydrogenase (R-HicDH), 2-oxohexanoate |
| R-2-hydroxyisocaproate dehydrogenase (R-HicDH) | Lactobacillus casei | 2-oxooctanoate | 139 | 0.12 | 1.2 × 10³ | pH 7 | doi:10.1016/0141-0229(92)90022-g | Open record: R-2-hydroxyisocaproate dehydrogenase (R-HicDH), 2-oxooctanoate |
| R-2-hydroxyisocaproate dehydrogenase (R-HicDH) | Lactobacillus casei | 2-oxopentanoate | 197 | 0.12 | 1.6 × 10³ | pH 7 | doi:10.1016/0141-0229(92)90022-g | Open record: R-2-hydroxyisocaproate dehydrogenase (R-HicDH), 2-oxopentanoate |
| R-2-hydroxyisocaproate dehydrogenase (R-HicDH) | Lactobacillus casei | 2-oxopropanoate | 125 | 86 | 1.5 | pH 7 | doi:10.1016/0141-0229(92)90022-g | Open record: R-2-hydroxyisocaproate dehydrogenase (R-HicDH), 2-oxopropanoate |
| R-2-hydroxyisocaproate dehydrogenase (R-HicDH) | Lactobacillus casei | 3-(1H-indol-3-yl)-2-oxopropanoate | 843 | 0.25 | 3.4 × 10³ calc. | pH 7 | doi:10.1016/0141-0229(92)90022-g | Open record: R-2-hydroxyisocaproate dehydrogenase (R-HicDH), 3-(1H-indol-3-yl)-2-oxopropanoate |
| R-2-hydroxyisocaproate dehydrogenase (R-HicDH) | Lactobacillus casei | 3-bromo-2-oxopropanoate | 1.29 × 10³ | 0.48 | 2.7 × 10³ | pH 7 | doi:10.1016/0141-0229(92)90022-g | Open record: R-2-hydroxyisocaproate dehydrogenase (R-HicDH), 3-bromo-2-oxopropanoate |
| R-2-hydroxyisocaproate dehydrogenase (R-HicDH) | Lactobacillus casei | 3-methyl-2-oxopentanoate | 34 | 1.6 | 21 | pH 7 | doi:10.1016/0141-0229(92)90022-g | Open record: R-2-hydroxyisocaproate dehydrogenase (R-HicDH), 3-methyl-2-oxopentanoate |
| R-2-hydroxyisocaproate dehydrogenase (R-HicDH) | Lactobacillus casei | 4-(methylsulfanyl)-2-oxobutanoate | 196 | 0.96 | 200 | pH 7 | doi:10.1016/0141-0229(92)90022-g | Open record: R-2-hydroxyisocaproate dehydrogenase (R-HicDH), 4-(methylsulfanyl)-2-oxobutanoate |
| R-2-hydroxyisocaproate dehydrogenase (R-HicDH) | Lactobacillus casei | 4-methyl-2-oxopentanoate | 84 | 0.4 | 210 | pH 7 | doi:10.1016/0141-0229(92)90022-g | Open record: R-2-hydroxyisocaproate dehydrogenase (R-HicDH), 4-methyl-2-oxopentanoate |
| R-2-hydroxyisocaproate dehydrogenase (R-HicDH) | Lactobacillus casei | hydroxyphenylpyruvate | 788 | 0.6 | 1.3 × 10³ | pH 7 | doi:10.1016/0141-0229(92)90022-g | Open record: R-2-hydroxyisocaproate dehydrogenase (R-HicDH), hydroxyphenylpyruvate |
| VanH | Enterococcus faecium | NADH | — | 0.021 | — | pH 5.6 | PMID 1931965 | Open record: VanH, NADH |
| VanH | Enterococcus faecium | NADPH | — | 0.002 | — | pH 5.6 | PMID 1931965 | Open record: VanH, NADPH |
| VanH | Enterococcus faecium | pyruvate | 40 | 1.45 | 28 | pH 5.6 | PMID 1931965 | Open record: VanH, pyruvate |
| VanH | Enterococcus faecium | α-ketobutyrate | 35 | 2.6 | 14 | pH 5.6 | PMID 1931965 | Open record: VanH, α-ketobutyrate |
| VanH | Enterococcus faecium | α-ketocaproate | 2.4 | 20 | 0.12 | pH 5.6 | PMID 1931965 | Open record: VanH, α-ketocaproate |
| VanH | Enterococcus faecium | α-ketoisocaproate | 5.2 | 31 | 0.168 | pH 5.6 | PMID 1931965 | Open record: VanH, α-ketoisocaproate |
| VanH | Enterococcus faecium | α-ketoisovalerate | 5.2 | 150 | 0.035 | pH 5.6 | PMID 1931965 | Open record: VanH, α-ketoisovalerate |
| VanH | Enterococcus faecium | α-ketovalerate | 35 | 40 | 0.88 | pH 5.6 | PMID 1931965 | Open record: VanH, α-ketovalerate |