EC 1.1.1.28: D-lactate dehydrogenase

OxidoreductasesOpen in Browse

CatLog read 228 records for EC 1.1.1.28 from 17 papers, for 16 organisms. Names in these papers: D-lactate dehydrogenase, D-lactate dehydrogenase (FNLDH, FN0511 protein), D-lactate dehydrogenase (PALDH, PA0927 protein), D-lactate dehydrogenase (paLDH) and 12 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 189 records for EC 1.1.1.28 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.1.1.28 in Browse.

Papers

Papers with records for EC 1.1.1.28
Paper	Organisms	Records
Diverse allosteric and catalytic functions of tetrameric d-lactate dehydrogenases from three Gram-negative bacteria	Escherichia coli, Fusobacterium nucleatum subsp. nucleatum and 1 more	48
Recognition site for the side chain of 2-ketoacid substrate in d-lactate dehydrogenase	Lactobacillus pentosus	42
Glutamate 264 modulates the pH dependence of the NAD(+)-dependent D-lactate dehydrogenase	Lactobacillus delbrueckii subsp. bulgaricus	24
Molecular basis for vancomycin resistance in Enterococcus faecium BM4147: biosynthesis of a depsipeptide peptidoglycan precursor by vancomycin resistance proteins VanH and VanA	Enterococcus faecium, Lactobacillus leichmanii and 1 more	18
Engineering D-Lactate Dehydrogenase from Pediococcus acidilactici for Improved Activity on 2-Hydroxy Acids with Bulky C₃ Functional Group	Pediococcus acidilactici	14
Engineering d-Lactate Dehydrogenase to Favor an Non-natural Cofactor Nicotinamide Cytosine Dinucleotide	Lactobacillus helveticus	10
Essential role of arginine 235 in the substrate-binding of Lactobacillus plantarum D-lactate dehydrogenase	Lactobacillus plantarum	10
Cloning and overexpression of Lactobacillus helveticus D-lactate dehydrogenase gene in Escherichia coli	Lactobacillus helveticus	9
Primary structure, physicochemical properties, and chemical modification of NAD(+)-dependent D-lactate dehydrogenase. Evidence for the presence of Arg-235, His-303, Tyr-101, and Trp-19 at or near…	Lactobacillus delbrueckii subsp. bulgaricus	8
Distinct conformation-mediated functions of an active site loop in the catalytic reactions of NAD-dependent D-lactate dehydrogenase and formate dehydrogenase	Lactobacillus pentosus	8
Structural Insights into Malic Enzyme Variants Favoring an Unnatural Redox Cofactor	Lactobacillus helveticus	8
An aldo-keto reductase with 2-keto-l-gulonate reductase activity functions in l-tartaric acid biosynthesis from vitamin C in Vitis vinifera	Vitis vinifera	7
Histidine 296 is essential for the catalysis in Lactobacillus plantarum D-lactate dehydrogenase	Lactobacillus plantarum	7
doi:10.1016/j.procbio.2012.11.013	Lactobacillus jensenii	6
Highly stereoselective biosynthesis of (R)-α-hydroxy carboxylic acids through rationally re-designed mutation of D-lactate dehydrogenase	Lactobacillus bulgaricus	4
Relative catalytic efficiencies and transcript levels of three d- and two l-lactate dehydrogenases for optically pure d-lactate production in Sporolactobacillus inulinus	Sporolactobacillus inulinus	3
Control of glucose utilization in working perfused rat heart	Rattus norvegicus	2

Records

Records for EC 1.1.1.28 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
2-keto-L-gulonate reductase (Vv2KGR)	Vitis vinifera	2-keto-L-gulonic acid1 mM NADH; cosubstrate NADH	9.52	1.561	6.10 calc.	pH 7.5, 37 °C	PMID 31488549	Open record: 2-keto-L-gulonate reductase (Vv2KGR), 2-keto-L-gulonic acid
2-keto-L-gulonate reductase (Vv2KGR)	Vitis vinifera	2-keto-L-gulonic acid1 mM NADPH; cosubstrate NADPH	4.178	0.7	6.0 calc.	pH 7.5, 37 °C	PMID 31488549	Open record: 2-keto-L-gulonate reductase (Vv2KGR), 2-keto-L-gulonic acid
2-keto-L-gulonate reductase (Vv2KGR)	Vitis vinifera	3-hydroxypyruvate	6.973	0.096	73 calc.	pH 7.5, 37 °C	PMID 31488549	Open record: 2-keto-L-gulonate reductase (Vv2KGR), 3-hydroxypyruvate
2-keto-L-gulonate reductase (Vv2KGR)	Vitis vinifera	glyoxylate1 mM NADH; cosubstrate NADH	192.1	0.248	775 calc.	pH 7.5, 37 °C	PMID 31488549	Open record: 2-keto-L-gulonate reductase (Vv2KGR), glyoxylate
2-keto-L-gulonate reductase (Vv2KGR)	Vitis vinifera	glyoxylate1 mM NADPH; cosubstrate NADPH	38.26	0.044	870 calc.	pH 7.5, 37 °C	PMID 31488549	Open record: 2-keto-L-gulonate reductase (Vv2KGR), glyoxylate
2-keto-L-gulonate reductase (Vv2KGR)	Vitis vinifera	pyruvate1 mM NADH; cosubstrate NADH	0.01517	3.453	0.004393 calc.	pH 7.5, 37 °C	PMID 31488549	Open record: 2-keto-L-gulonate reductase (Vv2KGR), pyruvate
2-keto-L-gulonate reductase (Vv2KGR)	Vitis vinifera	pyruvate1 mM NADPH; cosubstrate NADPH	0.01223	1.371	0.008920 calc.	pH 7.5, 37 °C	PMID 31488549	Open record: 2-keto-L-gulonate reductase (Vv2KGR), pyruvate
D-lactate dehydrogenase	Lactobacillus delbrueckii subsp. bulgaricus	2-oxobutanoate	100	12.5	8	pH 7.5, 25 °C	PMID 1569100	Open record: D-lactate dehydrogenase, 2-oxobutanoate
D-lactate dehydrogenase	Lactobacillus delbrueckii subsp. bulgaricus	Bromopyruvate	540	10	54	pH 7.5, 25 °C	PMID 1356978	Open record: D-lactate dehydrogenase, Bromopyruvate
D-lactate dehydrogenase	Lactobacillus delbrueckii subsp. bulgaricus	Bromopyruvate50 mM MES	885	7.2	123	pH 5.5, 25 °C	PMID 1356978	Open record: D-lactate dehydrogenase, Bromopyruvate
D-lactate dehydrogenase	Lactobacillus delbrueckii subsp. bulgaricus	Bromopyruvate50 mM MES with 100 mM sodium acetate	1115	—	—	pH 5.5, 25 °C	PMID 1356978	Open record: D-lactate dehydrogenase, Bromopyruvate
D-lactate dehydrogenase	Lactobacillus delbrueckii subsp. bulgaricus	bromopyruvate	546	6	91	pH 7.5, 25 °C	PMID 1569100	Open record: D-lactate dehydrogenase, bromopyruvate
D-lactate dehydrogenase	Lactobacillus delbrueckii subsp. bulgaricus	D-lactate	150	133	1.13	pH 7.5, 25 °C	PMID 1569100	Open record: D-lactate dehydrogenase, D-lactate
D-lactate dehydrogenase	Lactobacillus delbrueckii subsp. bulgaricus	Glyoxylate	864	100	8.6	pH 7.5, 25 °C	PMID 1356978	Open record: D-lactate dehydrogenase, Glyoxylate
D-lactate dehydrogenase	Lactobacillus delbrueckii subsp. bulgaricus	Glyoxylate50 mM MES	292	2.8	104	pH 5.5, 25 °C	PMID 1356978	Open record: D-lactate dehydrogenase, Glyoxylate
D-lactate dehydrogenase	Lactobacillus delbrueckii subsp. bulgaricus	Glyoxylate50 mM MES with 100 mM sodium acetate	584	—	—	pH 5.5, 25 °C	PMID 1356978	Open record: D-lactate dehydrogenase, Glyoxylate
D-lactate dehydrogenase	Lactobacillus delbrueckii subsp. bulgaricus	glyoxylate	864	10	86.4	pH 7.5, 25 °C	PMID 1569100	Open record: D-lactate dehydrogenase, glyoxylate
D-lactate dehydrogenase	Lactobacillus delbrueckii subsp. bulgaricus	Oxalacetate	1.2 × 10³	7	170	pH 7.5, 25 °C	PMID 1356978	Open record: D-lactate dehydrogenase, Oxalacetate
D-lactate dehydrogenase	Lactobacillus delbrueckii subsp. bulgaricus	Oxalacetate50 mM MES	221	2.5	88	pH 5.5, 25 °C	PMID 1356978	Open record: D-lactate dehydrogenase, Oxalacetate
D-lactate dehydrogenase	Lactobacillus delbrueckii subsp. bulgaricus	Oxalacetate50 mM MES with 100 mM sodium acetate	720	—	—	pH 5.5, 25 °C	PMID 1356978	Open record: D-lactate dehydrogenase, Oxalacetate
D-lactate dehydrogenase	Lactobacillus delbrueckii subsp. bulgaricus	oxaloacetate	1.2 × 10³	9	133	pH 7.5, 25 °C	PMID 1569100	Open record: D-lactate dehydrogenase, oxaloacetate
D-lactate dehydrogenase	Lactobacillus delbrueckii subsp. bulgaricus	phenylpyruvate	15	—	—	pH 7.5, 25 °C	PMID 1569100	Open record: D-lactate dehydrogenase, phenylpyruvate
D-lactate dehydrogenase	Lactobacillus delbrueckii subsp. bulgaricus	Pyruvate	1.68 × 10³	1.5	1.05 × 10³	pH 7.5, 25 °C	PMID 1356978	Open record: D-lactate dehydrogenase, Pyruvate
D-lactate dehydrogenase	Lactobacillus delbrueckii subsp. bulgaricus	Pyruvate50 mM MES	674	0.2	3.37 × 10³	pH 5.5, 25 °C	PMID 1356978	Open record: D-lactate dehydrogenase, Pyruvate
D-lactate dehydrogenase	Lactobacillus delbrueckii subsp. bulgaricus	Pyruvate50 mM MES with 100 mM sodium acetate	1.34 × 10³	—	—	pH 5.5, 25 °C	PMID 1356978	Open record: D-lactate dehydrogenase, Pyruvate
D-lactate dehydrogenase	Lactobacillus delbrueckii subsp. bulgaricus	pyruvatenative enzyme purified from L. bulgaricus cells	1.68 × 10³	1.6	1.05 × 10³	pH 7.5, 25 °C	PMID 1569100	Open record: D-lactate dehydrogenase, pyruvate
D-lactate dehydrogenase	Lactobacillus delbrueckii subsp. bulgaricus	pyruvatepH 7.5	—	1.6	—	pH 7.5, 25 °C	PMID 1569100	Open record: D-lactate dehydrogenase, pyruvate
D-lactate dehydrogenasevariant E264G	Lactobacillus delbrueckii subsp. bulgaricus	Bromopyruvate	16	—	—	pH 7.5, 25 °C	PMID 1356978	Open record: D-lactate dehydrogenase variant E264G, Bromopyruvate
D-lactate dehydrogenasevariant E264G	Lactobacillus delbrueckii subsp. bulgaricus	Bromopyruvate50 mM MES	604	12	50	pH 5.5, 25 °C	PMID 1356978	Open record: D-lactate dehydrogenase variant E264G, Bromopyruvate
D-lactate dehydrogenasevariant E264G	Lactobacillus delbrueckii subsp. bulgaricus	Bromopyruvate50 mM MES with 100 mM sodium acetate	477	—	—	pH 5.5, 25 °C	PMID 1356978	Open record: D-lactate dehydrogenase variant E264G, Bromopyruvate
D-lactate dehydrogenasevariant E264G	Lactobacillus delbrueckii subsp. bulgaricus	Glyoxylate	850	100	8.5	pH 7.5, 25 °C	PMID 1356978	Open record: D-lactate dehydrogenase variant E264G, Glyoxylate
D-lactate dehydrogenasevariant E264G	Lactobacillus delbrueckii subsp. bulgaricus	Glyoxylate50 mM MES	620	20	31	pH 5.5, 25 °C	PMID 1356978	Open record: D-lactate dehydrogenase variant E264G, Glyoxylate
D-lactate dehydrogenasevariant E264G	Lactobacillus delbrueckii subsp. bulgaricus	Glyoxylate50 mM MES with 100 mM sodium acetate	492	—	—	pH 5.5, 25 °C	PMID 1356978	Open record: D-lactate dehydrogenase variant E264G, Glyoxylate
D-lactate dehydrogenasevariant E264G	Lactobacillus delbrueckii subsp. bulgaricus	Oxalacetate	9	—	—	pH 7.5, 25 °C	PMID 1356978	Open record: D-lactate dehydrogenase variant E264G, Oxalacetate
D-lactate dehydrogenasevariant E264G	Lactobacillus delbrueckii subsp. bulgaricus	Oxalacetate50 mM MES	980	2.4	408	pH 5.5, 25 °C	PMID 1356978	Open record: D-lactate dehydrogenase variant E264G, Oxalacetate
D-lactate dehydrogenasevariant E264G	Lactobacillus delbrueckii subsp. bulgaricus	Oxalacetate50 mM MES with 100 mM sodium acetate	464	—	—	pH 5.5, 25 °C	PMID 1356978	Open record: D-lactate dehydrogenase variant E264G, Oxalacetate
D-lactate dehydrogenasevariant E264G	Lactobacillus delbrueckii subsp. bulgaricus	Pyruvate	260	15	17	pH 7.5, 25 °C	PMID 1356978	Open record: D-lactate dehydrogenase variant E264G, Pyruvate
D-lactate dehydrogenasevariant E264G	Lactobacillus delbrueckii subsp. bulgaricus	Pyruvate50 mM MES	1.42 × 10³	2.5	568	pH 5.5, 25 °C	PMID 1356978	Open record: D-lactate dehydrogenase variant E264G, Pyruvate
D-lactate dehydrogenasevariant E264G	Lactobacillus delbrueckii subsp. bulgaricus	Pyruvate50 mM MES with 100 mM sodium acetate	2.5 × 10³	—	—	pH 5.5, 25 °C	PMID 1356978	Open record: D-lactate dehydrogenase variant E264G, Pyruvate
D-lactate dehydrogenase	Lactobacillus helveticus	2-oxobutyrate	126	30	4.2	pH 7.5, 25 °C	PMID 1396685	Open record: D-lactate dehydrogenase, 2-oxobutyrate
D-lactate dehydrogenase	Lactobacillus helveticus	bromopyruvate	830	13	64	pH 7.5, 25 °C	PMID 1396685	Open record: D-lactate dehydrogenase, bromopyruvate
D-lactate dehydrogenase	Lactobacillus helveticus	D-lactate	100	66	1.5	pH 7.5, 25 °C	PMID 1396685	Open record: D-lactate dehydrogenase, D-lactate
D-lactate dehydrogenase	Lactobacillus helveticus	glyoxylate	351	67	5.2	pH 7.5, 25 °C	PMID 1396685	Open record: D-lactate dehydrogenase, glyoxylate
D-lactate dehydrogenase	Lactobacillus helveticus	NADH	100	0.01	1 × 10⁴	pH 7.5, 25 °C	PMID 1396685	Open record: D-lactate dehydrogenase, NADH
D-lactate dehydrogenase	Lactobacillus helveticus	oxalacetatenative enzyme purified from L. helveticus ATCC 15009	295	3.6	82	pH 7.5, 25 °C	PMID 1396685	Open record: D-lactate dehydrogenase, oxalacetate
D-lactate dehydrogenase	Lactobacillus helveticus	oxalacetaterecombinant; purified	250	4.2	60 calc.	pH 7.5, 25 °C	PMID 1396685	Open record: D-lactate dehydrogenase, oxalacetate
D-lactate dehydrogenase	Lactobacillus helveticus	pyruvatenative enzyme purified from L. helveticus ATCC 15009	1392	1.25	1.1 × 10³	pH 7.5, 25 °C	PMID 1396685	Open record: D-lactate dehydrogenase, pyruvate
D-lactate dehydrogenase	Lactobacillus helveticus	pyruvaterecombinant; purified	1.33 × 10³	1.5	890 calc.	pH 7.5, 25 °C	PMID 1396685	Open record: D-lactate dehydrogenase, pyruvate
D-lactate dehydrogenasevariant V152R/I177D/N213I	Lactobacillus helveticus	nicotinamide adenine dinucleotide	0.1	1.63	0.06		PMID 33523590	Open record: D-lactate dehydrogenase variant V152R/I177D/N213I, nicotinamide adenine dinucleotide
D-lactate dehydrogenasevariant V152R/I177D/N213I	Lactobacillus helveticus	nicotinamide cytosine dinucleotide	1.3	1.41	0.92		PMID 33523590	Open record: D-lactate dehydrogenase variant V152R/I177D/N213I, nicotinamide cytosine dinucleotide
D-lactate dehydrogenasevariant V152R/I177F/N213I	Lactobacillus helveticus	nicotinamide adenine dinucleotide	0.03	2.11	0.01		PMID 33523590	Open record: D-lactate dehydrogenase variant V152R/I177F/N213I, nicotinamide adenine dinucleotide
D-lactate dehydrogenasevariant V152R/I177F/N213I	Lactobacillus helveticus	nicotinamide cytosine dinucleotide	1.45	1.37	1.06		PMID 33523590	Open record: D-lactate dehydrogenase variant V152R/I177F/N213I, nicotinamide cytosine dinucleotide
D-lactate dehydrogenasevariant V152R/I177R/N213I	Lactobacillus helveticus	nicotinamide adenine dinucleotide	0.05	5.2	0.01		PMID 33523590	Open record: D-lactate dehydrogenase variant V152R/I177R/N213I, nicotinamide adenine dinucleotide
D-lactate dehydrogenasevariant V152R/I177R/N213I	Lactobacillus helveticus	nicotinamide cytosine dinucleotide	1.05	0.66	1.59		PMID 33523590	Open record: D-lactate dehydrogenase variant V152R/I177R/N213I, nicotinamide cytosine dinucleotide
D-lactate dehydrogenasevariant V152R/I177Y/N213I	Lactobacillus helveticus	nicotinamide adenine dinucleotide	0.07	0.62	0.11		PMID 33523590	Open record: D-lactate dehydrogenase variant V152R/I177Y/N213I, nicotinamide adenine dinucleotide
D-lactate dehydrogenasevariant V152R/I177Y/N213I	Lactobacillus helveticus	nicotinamide cytosine dinucleotide	2.78	1.14	2.44		PMID 33523590	Open record: D-lactate dehydrogenase variant V152R/I177Y/N213I, nicotinamide cytosine dinucleotide
D-lactate dehydrogenase	Lactobacillus leichmanii	NADH	—	0.01	—	pH 5.6	PMID 1931965	Open record: D-lactate dehydrogenase, NADH
D-lactate dehydrogenase	Lactobacillus leichmanii	NADPH	—	0.19	—	pH 5.6	PMID 1931965	Open record: D-lactate dehydrogenase, NADPH
D-lactate dehydrogenase	Lactobacillus leichmanii	phenylpyruvate	55	11.7	2.9	pH 5.6	PMID 1931965	Open record: D-lactate dehydrogenase, phenylpyruvate
D-lactate dehydrogenase	Lactobacillus leichmanii	pyruvate	290	0.14	1.3 × 10³	pH 5.6	PMID 1931965	Open record: D-lactate dehydrogenase, pyruvate
D-lactate dehydrogenase	Lactobacillus leichmanii	α-ketobutyrate	252	34	4.6	pH 5.6	PMID 1931965	Open record: D-lactate dehydrogenase, α-ketobutyrate
D-lactate dehydrogenase	Lactobacillus pentosus	2-ketobutyrate	120	8.1	15	pH 5.5, 30 °C	PMID 15734738	Open record: D-lactate dehydrogenase, 2-ketobutyrate
D-lactate dehydrogenase	Lactobacillus pentosus	2-Ketobutyrate	118	8.1	15	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase, 2-Ketobutyrate
D-lactate dehydrogenase	Lactobacillus pentosus	2-Ketocaproate	13.3	21	0.63	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase, 2-Ketocaproate
D-lactate dehydrogenase	Lactobacillus pentosus	2-Ketoglutarate	0.51	15.5	0.03	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase, 2-Ketoglutarate
D-lactate dehydrogenase	Lactobacillus pentosus	2-Ketoisocaproate	11.1	31	0.36	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase, 2-Ketoisocaproate
D-lactate dehydrogenase	Lactobacillus pentosus	2-Ketoisovalerate	5.5	27	0.2	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase, 2-Ketoisovalerate
D-lactate dehydrogenase	Lactobacillus pentosus	2-Ketovalerate	5.7	17	0.34	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase, 2-Ketovalerate
D-lactate dehydrogenase	Lactobacillus pentosus	Glyoxylate	270	5.4	49	pH 5.5, 30 °C	PMID 15734738	Open record: D-lactate dehydrogenase, Glyoxylate
D-lactate dehydrogenase	Lactobacillus pentosus	Hydroxypyruvate	260	0.28	920	pH 5.5, 30 °C	PMID 15734738	Open record: D-lactate dehydrogenase, Hydroxypyruvate
D-lactate dehydrogenase	Lactobacillus pentosus	Hydroxypyruvate	257	0.28	920	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase, Hydroxypyruvate
D-lactate dehydrogenase	Lactobacillus pentosus	Oxaloacetate	280	2.2	127	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase, Oxaloacetate
D-lactate dehydrogenase	Lactobacillus pentosus	Phenylpyruvate	40	0.8	50	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase, Phenylpyruvate
D-lactate dehydrogenase	Lactobacillus pentosus	Pyruvate	320	0.12	2.7 × 10³	pH 5.5, 30 °C	PMID 15734738	Open record: D-lactate dehydrogenase, Pyruvate
D-lactate dehydrogenase	Lactobacillus pentosus	Pyruvate	321	0.12	2.7 × 10³	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase, Pyruvate
D-lactate dehydrogenasevariant F299G	Lactobacillus pentosus	Hydroxypyruvate	8.1	53	0.15	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant F299G, Hydroxypyruvate
D-lactate dehydrogenasevariant F299G	Lactobacillus pentosus	Phenylpyruvate	3.4	22	0.15	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant F299G, Phenylpyruvate
D-lactate dehydrogenasevariant F299G	Lactobacillus pentosus	Pyruvate	22	31	0.71	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant F299G, Pyruvate
D-lactate dehydrogenasevariant F299S	Lactobacillus pentosus	Hydroxypyruvate	35.8	18.6	1.9	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant F299S, Hydroxypyruvate
D-lactate dehydrogenasevariant F299S	Lactobacillus pentosus	Oxaloacetate	6.5	43.1	0.15	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant F299S, Oxaloacetate
D-lactate dehydrogenasevariant F299S	Lactobacillus pentosus	Phenylpyruvate	2.1	7.2	0.29	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant F299S, Phenylpyruvate
D-lactate dehydrogenasevariant F299S	Lactobacillus pentosus	Pyruvate	—	—	0.49	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant F299S, Pyruvate
D-lactate dehydrogenasevariant N97D	Lactobacillus pentosus	2-ketobutyrate	4.5	58	0.08	pH 5.5, 30 °C	PMID 15734738	Open record: D-lactate dehydrogenase variant N97D, 2-ketobutyrate
D-lactate dehydrogenasevariant N97D	Lactobacillus pentosus	Glyoxylate	50	72	0.7	pH 5.5, 30 °C	PMID 15734738	Open record: D-lactate dehydrogenase variant N97D, Glyoxylate
D-lactate dehydrogenasevariant N97D	Lactobacillus pentosus	Hydroxypyruvate	38	29	1.3	pH 5.5, 30 °C	PMID 15734738	Open record: D-lactate dehydrogenase variant N97D, Hydroxypyruvate
D-lactate dehydrogenasevariant N97D	Lactobacillus pentosus	Pyruvate	270	8.2	33	pH 5.5, 30 °C	PMID 15734738	Open record: D-lactate dehydrogenase variant N97D, Pyruvate
D-lactate dehydrogenasevariant Y52A	Lactobacillus pentosus	2-Ketobutyrate	41.5	20.8	2	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant Y52A, 2-Ketobutyrate
D-lactate dehydrogenasevariant Y52A	Lactobacillus pentosus	2-Ketocaproate	102	0.7	146	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant Y52A, 2-Ketocaproate
D-lactate dehydrogenasevariant Y52A	Lactobacillus pentosus	2-Ketoisocaproate	15.8	12.1	1.3	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant Y52A, 2-Ketoisocaproate
D-lactate dehydrogenasevariant Y52A	Lactobacillus pentosus	2-Ketovalerate	55.7	11.7	4.8	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant Y52A, 2-Ketovalerate
D-lactate dehydrogenasevariant Y52A	Lactobacillus pentosus	Hydroxypyruvate	104	17	6.1	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant Y52A, Hydroxypyruvate
D-lactate dehydrogenasevariant Y52A	Lactobacillus pentosus	Phenylpyruvate	232	0.03	7.73 × 10³	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant Y52A, Phenylpyruvate
D-lactate dehydrogenasevariant Y52A	Lactobacillus pentosus	Pyruvate	25.5	12.6	2	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant Y52A, Pyruvate
D-lactate dehydrogenasevariant Y52R	Lactobacillus pentosus	2-Ketocaproate	1.18	15.9	0.074	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant Y52R, 2-Ketocaproate
D-lactate dehydrogenasevariant Y52R	Lactobacillus pentosus	2-Ketovalerate	—	—	0.02	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant Y52R, 2-Ketovalerate
D-lactate dehydrogenasevariant Y52R	Lactobacillus pentosus	Hydroxypyruvate	13.8	20.2	0.68	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant Y52R, Hydroxypyruvate
D-lactate dehydrogenasevariant Y52R	Lactobacillus pentosus	Oxaloacetate	0.48	3.8	0.13	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant Y52R, Oxaloacetate
D-lactate dehydrogenasevariant Y52R	Lactobacillus pentosus	Phenylpyruvate	0.31	2.1	0.15	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant Y52R, Phenylpyruvate
D-lactate dehydrogenasevariant Y52R/F299G	Lactobacillus pentosus	2-Ketocaproate	0.36	14.1	0.026	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant Y52R/F299G, 2-Ketocaproate
D-lactate dehydrogenasevariant Y52R/F299G	Lactobacillus pentosus	2-Ketoglutarate	0.89	8.7	0.1	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant Y52R/F299G, 2-Ketoglutarate
D-lactate dehydrogenasevariant Y52R/F299G	Lactobacillus pentosus	Hydroxypyruvate	—	—	0.012	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant Y52R/F299G, Hydroxypyruvate
D-lactate dehydrogenasevariant Y52R/F299G	Lactobacillus pentosus	Phenylpyruvate	2.8	6.9	0.41	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant Y52R/F299G, Phenylpyruvate
D-lactate dehydrogenasevariant Y52T/F299S	Lactobacillus pentosus	Hydroxypyruvate	2.1	19	0.11	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant Y52T/F299S, Hydroxypyruvate
D-lactate dehydrogenasevariant Y52T/F299S	Lactobacillus pentosus	Phenylpyruvate	5.2	8.7	0.6	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant Y52T/F299S, Phenylpyruvate
D-lactate dehydrogenasevariant Y52V	Lactobacillus pentosus	2-Ketobutyrate	41	3.5	12	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant Y52V, 2-Ketobutyrate
D-lactate dehydrogenasevariant Y52V	Lactobacillus pentosus	2-Ketocaproate	51	0.3	170	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant Y52V, 2-Ketocaproate
D-lactate dehydrogenasevariant Y52V	Lactobacillus pentosus	2-Ketoisocaproate	17	0.7	24	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant Y52V, 2-Ketoisocaproate
D-lactate dehydrogenasevariant Y52V	Lactobacillus pentosus	2-Ketovalerate	102	0.8	128	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant Y52V, 2-Ketovalerate
D-lactate dehydrogenasevariant Y52V	Lactobacillus pentosus	Hydroxypyruvate	50	8.7	5.7	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant Y52V, Hydroxypyruvate
D-lactate dehydrogenasevariant Y52V	Lactobacillus pentosus	Phenylpyruvate	171	0.14	1.22 × 10³	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant Y52V, Phenylpyruvate
D-lactate dehydrogenasevariant Y52V	Lactobacillus pentosus	Pyruvate	37	13.1	2.8	pH 5.5, 30 °C	PMID 16428303	Open record: D-lactate dehydrogenase variant Y52V, Pyruvate
D-lactate dehydrogenase	Lactobacillus plantarum	2-ketobutyrate	700	25	28	30 °C	PMID 7961609	Open record: D-lactate dehydrogenase, 2-ketobutyrate
D-lactate dehydrogenase	Lactobacillus plantarum	D-lactate	260	7.7	34	pH 7.5, 30 °C	PMID 8349682	Open record: D-lactate dehydrogenase, D-lactate
D-lactate dehydrogenase	Lactobacillus plantarum	hydroxypyruvate	5 × 10³	2.5	2 × 10³	30 °C	PMID 7961609	Open record: D-lactate dehydrogenase, hydroxypyruvate
D-lactate dehydrogenase	Lactobacillus plantarum	phenylpyruvate	750	12	63	30 °C	PMID 7961609	Open record: D-lactate dehydrogenase, phenylpyruvate
D-lactate dehydrogenase	Lactobacillus plantarum	pyruvate	2.3 × 10³	0.5	4.6 × 10³	30 °C	PMID 7961609	Open record: D-lactate dehydrogenase, pyruvate
D-lactate dehydrogenase	Lactobacillus plantarum	pyruvate	1.5 × 10³	1	1.5 × 10³	pH 7, 30 °C	PMID 8349682	Open record: D-lactate dehydrogenase, pyruvate
D-lactate dehydrogenasevariant H205Y	Lactobacillus plantarum	D-lactate	120	4.3	28	pH 7.5, 30 °C	PMID 8349682	Open record: D-lactate dehydrogenase variant H205Y, D-lactate
D-lactate dehydrogenasevariant H205Y	Lactobacillus plantarum	pyruvate	1 × 10³	0.9	1.1 × 10³	pH 7, 30 °C	PMID 8349682	Open record: D-lactate dehydrogenase variant H205Y, pyruvate
D-lactate dehydrogenasevariant H296Q	Lactobacillus plantarum	pyruvate	—	—	2 × 10⁻⁴	pH 7, 30 °C	PMID 8349682	Open record: D-lactate dehydrogenase variant H296Q, pyruvate
D-lactate dehydrogenasevariant H296Y	Lactobacillus plantarum	D-lactate	—	—	2.4 × 10⁻⁵	pH 7.5, 30 °C	PMID 8349682	Open record: D-lactate dehydrogenase variant H296Y, D-lactate
D-lactate dehydrogenasevariant H296Y	Lactobacillus plantarum	pyruvate	0.074	0.7	0.1	pH 7, 30 °C	PMID 8349682	Open record: D-lactate dehydrogenase variant H296Y, pyruvate
D-lactate dehydrogenasevariant R235K	Lactobacillus plantarum	2-ketobutyrate	0.1	40	0.0025	30 °C	PMID 7961609	Open record: D-lactate dehydrogenase variant R235K, 2-ketobutyrate
D-lactate dehydrogenasevariant R235K	Lactobacillus plantarum	hydroxypyruvate	10	80	0.13	30 °C	PMID 7961609	Open record: D-lactate dehydrogenase variant R235K, hydroxypyruvate
D-lactate dehydrogenasevariant R235K	Lactobacillus plantarum	phenylpyruvate	0.24	20	0.012	30 °C	PMID 7961609	Open record: D-lactate dehydrogenase variant R235K, phenylpyruvate
D-lactate dehydrogenasevariant R235K	Lactobacillus plantarum	pyruvate	12	50	0.24	30 °C	PMID 7961609	Open record: D-lactate dehydrogenase variant R235K, pyruvate
D-lactate dehydrogenasevariant R235Q	Lactobacillus plantarum	hydroxypyruvate	0.6	120	0.005	30 °C	PMID 7961609	Open record: D-lactate dehydrogenase variant R235Q, hydroxypyruvate
D-lactate dehydrogenasevariant R235Q	Lactobacillus plantarum	pyruvate	12	500	0.024	30 °C	PMID 7961609	Open record: D-lactate dehydrogenase variant R235Q, pyruvate
D-lactate dehydrogenase	Leuconostoc mesenteroides	NADH	—	0.008	—	pH 5.6	PMID 1931965	Open record: D-lactate dehydrogenase, NADH
D-lactate dehydrogenase	Leuconostoc mesenteroides	NADPH	—	0.096	—	pH 5.6	PMID 1931965	Open record: D-lactate dehydrogenase, NADPH
D-lactate dehydrogenase	Leuconostoc mesenteroides	phenylpyruvate	1.15 × 10³	6.7	100	pH 5.6	PMID 1931965	Open record: D-lactate dehydrogenase, phenylpyruvate
D-lactate dehydrogenase	Leuconostoc mesenteroides	pyruvate	2.68 × 10³	0.075	2.2 × 10⁴	pH 5.6	PMID 1931965	Open record: D-lactate dehydrogenase, pyruvate
D-lactate dehydrogenase	Leuconostoc mesenteroides	α-ketobutyrate	1.9 × 10³	12.5	92	pH 5.6	PMID 1931965	Open record: D-lactate dehydrogenase, α-ketobutyrate
D-lactate dehydrogenase (ECLDH, ECD_01352 protein)	Escherichia coli	2-oxobutanoate	31	—	—	pH 7, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (ECLDH, ECD_01352 protein), 2-oxobutanoate
D-lactate dehydrogenase (ECLDH, ECD_01352 protein)	Escherichia coli	Glyoxylate	100	—	—	pH 7, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (ECLDH, ECD_01352 protein), Glyoxylate
D-lactate dehydrogenase (ECLDH, ECD_01352 protein)	Escherichia coli	Hydroxypyruvate	50	12	4.2	pH 7, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (ECLDH, ECD_01352 protein), Hydroxypyruvate
D-lactate dehydrogenase (ECLDH, ECD_01352 protein)	Escherichia coli	NADH	640	0.055	1.2 × 10⁴	pH 7, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (ECLDH, ECD_01352 protein), NADH
D-lactate dehydrogenase (ECLDH, ECD_01352 protein)	Escherichia coli	NADHno effector	710	0.088	8.1 × 10³	pH 8, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (ECLDH, ECD_01352 protein), NADH
D-lactate dehydrogenase (ECLDH, ECD_01352 protein)	Escherichia coli	NADHwith 5 mM FBP	730	0.092	8 × 10³	pH 8, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (ECLDH, ECD_01352 protein), NADH
D-lactate dehydrogenase (ECLDH, ECD_01352 protein)	Escherichia coli	NADHwith 2.4 mM MgCl2	690	0.09	7.7 × 10³	pH 8, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (ECLDH, ECD_01352 protein), NADH
D-lactate dehydrogenase (ECLDH, ECD_01352 protein)	Escherichia coli	Oxaloacetate	1.1 × 10³	54	21	pH 7, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (ECLDH, ECD_01352 protein), Oxaloacetate
D-lactate dehydrogenase (ECLDH, ECD_01352 protein)	Escherichia coli	Pyruvate	410	—	—	pH 7, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (ECLDH, ECD_01352 protein), Pyruvate
D-lactate dehydrogenase (ECLDH, ECD_01352 protein)	Escherichia coli	Pyruvateno effector	380	—	—	pH 8, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (ECLDH, ECD_01352 protein), Pyruvate
D-lactate dehydrogenase (ECLDH, ECD_01352 protein)	Escherichia coli	Pyruvatewith 5 mM FBP	400	—	—	pH 8, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (ECLDH, ECD_01352 protein), Pyruvate
D-lactate dehydrogenase (ECLDH, ECD_01352 protein)	Escherichia coli	Pyruvatewith 2.4 mM MgCl2	370	—	—	pH 8, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (ECLDH, ECD_01352 protein), Pyruvate
D-lactate dehydrogenase (ECLDH, ECD_01352 protein)	Escherichia coli	pyruvate	670	5.6	120 calc.	pH 7, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (ECLDH, ECD_01352 protein), pyruvate
D-lactate dehydrogenase (FNLDH, FN0511 protein)	Fusobacterium nucleatum subsp. nucleatum	2-oxobutanoate	140	0.31	440	pH 7, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (FNLDH, FN0511 protein), 2-oxobutanoate
D-lactate dehydrogenase (FNLDH, FN0511 protein)	Fusobacterium nucleatum subsp. nucleatum	2-oxohexanoate	230	2.6	87	pH 7, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (FNLDH, FN0511 protein), 2-oxohexanoate
D-lactate dehydrogenase (FNLDH, FN0511 protein)	Fusobacterium nucleatum subsp. nucleatum	2-oxopentanoate	140	0.68	200	pH 7, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (FNLDH, FN0511 protein), 2-oxopentanoate
D-lactate dehydrogenase (FNLDH, FN0511 protein)	Fusobacterium nucleatum subsp. nucleatum	3-methyl-2-oxobutanoate	120	3.5	35	pH 7, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (FNLDH, FN0511 protein), 3-methyl-2-oxobutanoate
D-lactate dehydrogenase (FNLDH, FN0511 protein)	Fusobacterium nucleatum subsp. nucleatum	4-methyl-2-oxopentanoate	200	3.8	53	pH 7, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (FNLDH, FN0511 protein), 4-methyl-2-oxopentanoate
D-lactate dehydrogenase (FNLDH, FN0511 protein)	Fusobacterium nucleatum subsp. nucleatum	Glyoxylate	11	18	0.7	pH 7, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (FNLDH, FN0511 protein), Glyoxylate
D-lactate dehydrogenase (FNLDH, FN0511 protein)	Fusobacterium nucleatum subsp. nucleatum	Hydroxypyruvate	160	18	8.7	pH 7, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (FNLDH, FN0511 protein), Hydroxypyruvate
D-lactate dehydrogenase (FNLDH, FN0511 protein)	Fusobacterium nucleatum subsp. nucleatum	NADH	98	0.022	4.4 × 10³	pH 7, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (FNLDH, FN0511 protein), NADH
D-lactate dehydrogenase (FNLDH, FN0511 protein)	Fusobacterium nucleatum subsp. nucleatum	NADHno effector	90	—	—	pH 8, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (FNLDH, FN0511 protein), NADH
D-lactate dehydrogenase (FNLDH, FN0511 protein)	Fusobacterium nucleatum subsp. nucleatum	NADHwith 10 mM FBP	80	—	—	pH 8, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (FNLDH, FN0511 protein), NADH
D-lactate dehydrogenase (FNLDH, FN0511 protein)	Fusobacterium nucleatum subsp. nucleatum	NADHwith 5 mM MgCl2	110	—	—	pH 8, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (FNLDH, FN0511 protein), NADH
D-lactate dehydrogenase (FNLDH, FN0511 protein)	Fusobacterium nucleatum subsp. nucleatum	Oxaloacetate	80	2.5	31	pH 7, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (FNLDH, FN0511 protein), Oxaloacetate
D-lactate dehydrogenase (FNLDH, FN0511 protein)	Fusobacterium nucleatum subsp. nucleatum	Phenylpyruvate	120	11	11	pH 7, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (FNLDH, FN0511 protein), Phenylpyruvate
D-lactate dehydrogenase (FNLDH, FN0511 protein)	Fusobacterium nucleatum subsp. nucleatum	Pyruvate	80	0.34	230	pH 7, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (FNLDH, FN0511 protein), Pyruvate
D-lactate dehydrogenase (FNLDH, FN0511 protein)	Fusobacterium nucleatum subsp. nucleatum	Pyruvateno effector	87	—	—	pH 8, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (FNLDH, FN0511 protein), Pyruvate
D-lactate dehydrogenase (FNLDH, FN0511 protein)	Fusobacterium nucleatum subsp. nucleatum	Pyruvatewith 10 mM FBP	100	—	—	pH 8, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (FNLDH, FN0511 protein), Pyruvate
D-lactate dehydrogenase (FNLDH, FN0511 protein)	Fusobacterium nucleatum subsp. nucleatum	Pyruvatewith 5 mM MgCl2	80	—	—	pH 8, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (FNLDH, FN0511 protein), Pyruvate
D-lactate dehydrogenase (FNLDH, FN0511 protein)	Fusobacterium nucleatum subsp. nucleatum	pyruvate	79	0.39	200 calc.	pH 7, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (FNLDH, FN0511 protein), pyruvate
D-lactate dehydrogenase (LhDLDH)	Lactobacillus helveticus	nicotinamide adenine dinucleotide	2.84	0.28	10.1		PMID 32175634	Open record: D-lactate dehydrogenase (LhDLDH), nicotinamide adenine dinucleotide
D-lactate dehydrogenase (LhDLDH)	Lactobacillus helveticus	nicotinamide cytosine dinucleotide	0.66	1.39	0.48		PMID 32175634	Open record: D-lactate dehydrogenase (LhDLDH), nicotinamide cytosine dinucleotide
D-lactate dehydrogenase (LhDLDH)variant V152R	Lactobacillus helveticus	nicotinamide adenine dinucleotide	2.14	0.92	2.3		PMID 32175634	Open record: D-lactate dehydrogenase (LhDLDH) variant V152R, nicotinamide adenine dinucleotide
D-lactate dehydrogenase (LhDLDH)variant V152R	Lactobacillus helveticus	nicotinamide cytosine dinucleotide	3.61	0.65	5.6		PMID 32175634	Open record: D-lactate dehydrogenase (LhDLDH) variant V152R, nicotinamide cytosine dinucleotide
D-lactate dehydrogenase (LhDLDH)variant V152R/I177K	Lactobacillus helveticus	nicotinamide adenine dinucleotide	0.62	0.87	0.71		PMID 32175634	Open record: D-lactate dehydrogenase (LhDLDH) variant V152R/I177K, nicotinamide adenine dinucleotide
D-lactate dehydrogenase (LhDLDH)variant V152R/I177K	Lactobacillus helveticus	nicotinamide cytosine dinucleotide	4.51	1.38	3.3		PMID 32175634	Open record: D-lactate dehydrogenase (LhDLDH) variant V152R/I177K, nicotinamide cytosine dinucleotide
D-lactate dehydrogenase (LhDLDH)variant V152R/I177K/N213I	Lactobacillus helveticus	nicotinamide adenine dinucleotide	0.08	1.05	0.074		PMID 32175634	Open record: D-lactate dehydrogenase (LhDLDH) variant V152R/I177K/N213I, nicotinamide adenine dinucleotide
D-lactate dehydrogenase (LhDLDH)variant V152R/I177K/N213I	Lactobacillus helveticus	nicotinamide cytosine dinucleotide	2.02	0.66	3.1		PMID 32175634	Open record: D-lactate dehydrogenase (LhDLDH) variant V152R/I177K/N213I, nicotinamide cytosine dinucleotide
D-lactate dehydrogenase (LhDLDH)variant V152R/N213E	Lactobacillus helveticus	nicotinamide adenine dinucleotide	0.08	1.6	0.049		PMID 32175634	Open record: D-lactate dehydrogenase (LhDLDH) variant V152R/N213E, nicotinamide adenine dinucleotide
D-lactate dehydrogenase (LhDLDH)variant V152R/N213E	Lactobacillus helveticus	nicotinamide cytosine dinucleotide	2.95	1.38	2.1		PMID 32175634	Open record: D-lactate dehydrogenase (LhDLDH) variant V152R/N213E, nicotinamide cytosine dinucleotide
D-lactate dehydrogenase (paLDH)	Pediococcus acidilactici	2-oxobutanoate	50.7	11	4.4	pH 5.5, 30 °C	PMID 31190286	Open record: D-lactate dehydrogenase (paLDH), 2-oxobutanoate
D-lactate dehydrogenase (paLDH)	Pediococcus acidilactici	3-methyl-2-oxobutanoate	33.9	38	0.892	pH 5.5, 30 °C	PMID 31190286	Open record: D-lactate dehydrogenase (paLDH), 3-methyl-2-oxobutanoate
D-lactate dehydrogenase (paLDH)	Pediococcus acidilactici	phenylpyruvate	41.3	2.6	15.9	pH 5.5, 30 °C	PMID 31190286	Open record: D-lactate dehydrogenase (paLDH), phenylpyruvate
D-lactate dehydrogenase (paLDH)variant Y51A	Pediococcus acidilactici	phenylpyruvate	269	0.16	1.72 × 10³	pH 5.5, 30 °C	PMID 31190286	Open record: D-lactate dehydrogenase (paLDH) variant Y51A, phenylpyruvate
D-lactate dehydrogenase (paLDH)variant Y51F	Pediococcus acidilactici	2-oxobutanoate	99.4	2.7	37.2	pH 5.5, 30 °C	PMID 31190286	Open record: D-lactate dehydrogenase (paLDH) variant Y51F, 2-oxobutanoate
D-lactate dehydrogenase (paLDH)variant Y51F	Pediococcus acidilactici	3-methyl-2-oxobutanoate	179	7.7	23.2	pH 5.5, 30 °C	PMID 31190286	Open record: D-lactate dehydrogenase (paLDH) variant Y51F, 3-methyl-2-oxobutanoate
D-lactate dehydrogenase (paLDH)variant Y51F	Pediococcus acidilactici	phenylpyruvate	391	0.22	1.88 × 10³	pH 5.5, 30 °C	PMID 31190286	Open record: D-lactate dehydrogenase (paLDH) variant Y51F, phenylpyruvate
D-lactate dehydrogenase (paLDH)variant Y51L	Pediococcus acidilactici	2-oxobutanoate	199	12	16.8	pH 5.5, 30 °C	PMID 31190286	Open record: D-lactate dehydrogenase (paLDH) variant Y51L, 2-oxobutanoate
D-lactate dehydrogenase (paLDH)variant Y51L	Pediococcus acidilactici	3-methyl-2-oxobutanoate	90.2	12	7.41	pH 5.5, 30 °C	PMID 31190286	Open record: D-lactate dehydrogenase (paLDH) variant Y51L, 3-methyl-2-oxobutanoate
D-lactate dehydrogenase (paLDH)variant Y51L	Pediococcus acidilactici	phenylpyruvate	376	0.17	2.2 × 10³	pH 5.5, 30 °C	PMID 31190286	Open record: D-lactate dehydrogenase (paLDH) variant Y51L, phenylpyruvate
D-lactate dehydrogenase (paLDH)variant Y51M	Pediococcus acidilactici	2-oxobutanoate	152	7.5	20.7	pH 5.5, 30 °C	PMID 31190286	Open record: D-lactate dehydrogenase (paLDH) variant Y51M, 2-oxobutanoate
D-lactate dehydrogenase (paLDH)variant Y51M	Pediococcus acidilactici	3-methyl-2-oxobutanoate	76.2	8.6	8.85	pH 5.5, 30 °C	PMID 31190286	Open record: D-lactate dehydrogenase (paLDH) variant Y51M, 3-methyl-2-oxobutanoate
D-lactate dehydrogenase (paLDH)variant Y51M	Pediococcus acidilactici	phenylpyruvate	462	0.22	2.13 × 10³	pH 5.5, 30 °C	PMID 31190286	Open record: D-lactate dehydrogenase (paLDH) variant Y51M, phenylpyruvate
D-lactate dehydrogenase (paLDH)variant Y51S	Pediococcus acidilactici	phenylpyruvate	239	0.4	612	pH 5.5, 30 °C	PMID 31190286	Open record: D-lactate dehydrogenase (paLDH) variant Y51S, phenylpyruvate
D-lactate dehydrogenase (PALDH, PA0927 protein)	Pseudomonas aeruginosa	2-oxobutanoate	100	0.64	150	pH 7, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (PALDH, PA0927 protein), 2-oxobutanoate
D-lactate dehydrogenase (PALDH, PA0927 protein)	Pseudomonas aeruginosa	2-oxohexanoate	160	5.8	27	pH 7, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (PALDH, PA0927 protein), 2-oxohexanoate
D-lactate dehydrogenase (PALDH, PA0927 protein)	Pseudomonas aeruginosa	2-oxopentanoate	69	4	18	pH 7, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (PALDH, PA0927 protein), 2-oxopentanoate
D-lactate dehydrogenase (PALDH, PA0927 protein)	Pseudomonas aeruginosa	4-methyl-2-oxopentanoate	39	12	3.2	pH 7, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (PALDH, PA0927 protein), 4-methyl-2-oxopentanoate
D-lactate dehydrogenase (PALDH, PA0927 protein)	Pseudomonas aeruginosa	Glyoxylate	880	6.8	130	pH 7, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (PALDH, PA0927 protein), Glyoxylate
D-lactate dehydrogenase (PALDH, PA0927 protein)	Pseudomonas aeruginosa	Hydroxypyruvate	420	3	140	pH 7, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (PALDH, PA0927 protein), Hydroxypyruvate
D-lactate dehydrogenase (PALDH, PA0927 protein)	Pseudomonas aeruginosa	NADH	310	0.019	1.7 × 10⁴	pH 7, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (PALDH, PA0927 protein), NADH
D-lactate dehydrogenase (PALDH, PA0927 protein)	Pseudomonas aeruginosa	NADHno effector	270	0.035	7.7 × 10³	pH 8, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (PALDH, PA0927 protein), NADH
D-lactate dehydrogenase (PALDH, PA0927 protein)	Pseudomonas aeruginosa	NADHwith 10 mM FBP	270	0.035	7.8 × 10³	pH 8, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (PALDH, PA0927 protein), NADH
D-lactate dehydrogenase (PALDH, PA0927 protein)	Pseudomonas aeruginosa	NADHwith 5 mM MgCl2	270	0.035	7.7 × 10³	pH 8, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (PALDH, PA0927 protein), NADH
D-lactate dehydrogenase (PALDH, PA0927 protein)	Pseudomonas aeruginosa	Oxaloacetate	410	1.7	230	pH 7, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (PALDH, PA0927 protein), Oxaloacetate
D-lactate dehydrogenase (PALDH, PA0927 protein)	Pseudomonas aeruginosa	Phenylpyruvate	18	7.1	2.6	pH 7, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (PALDH, PA0927 protein), Phenylpyruvate
D-lactate dehydrogenase (PALDH, PA0927 protein)	Pseudomonas aeruginosa	Pyruvate	400	0.1	4 × 10³	pH 7, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (PALDH, PA0927 protein), Pyruvate
D-lactate dehydrogenase (PALDH, PA0927 protein)	Pseudomonas aeruginosa	Pyruvateno effector	240	—	—	pH 8, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (PALDH, PA0927 protein), Pyruvate
D-lactate dehydrogenase (PALDH, PA0927 protein)	Pseudomonas aeruginosa	Pyruvatewith 10 mM FBP	240	—	—	pH 8, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (PALDH, PA0927 protein), Pyruvate
D-lactate dehydrogenase (PALDH, PA0927 protein)	Pseudomonas aeruginosa	Pyruvatewith 5 mM MgCl2	290	0.36	820	pH 8, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (PALDH, PA0927 protein), Pyruvate
D-lactate dehydrogenase (PALDH, PA0927 protein)	Pseudomonas aeruginosa	pyruvate	410	0.074	5.5 × 10³ calc.	pH 7, 30 °C	PMID 25401076	Open record: D-lactate dehydrogenase (PALDH, PA0927 protein), pyruvate
D-lactate dehydrogenase d-LDH1	Lactobacillus jensenii	NAD+	4.42	2.75	1.61	pH 8, 25 °C	doi:10.1016/j.procbio.2012.11.013	Open record: D-lactate dehydrogenase d-LDH1, NAD+
D-lactate dehydrogenase d-LDH1	Lactobacillus jensenii	NADH	144.4	0.7	206.3	pH 8, 25 °C	doi:10.1016/j.procbio.2012.11.013	Open record: D-lactate dehydrogenase d-LDH1, NADH
D-lactate dehydrogenase D-LDH1	Sporolactobacillus inulinus	pyruvate	75.8	0.47	161	pH 6, 35 °C	PMID 30066438	Open record: D-lactate dehydrogenase D-LDH1, pyruvate
D-lactate dehydrogenase d-LDH2	Lactobacillus jensenii	NAD+	3.65	2.58	1.41	pH 8, 25 °C	doi:10.1016/j.procbio.2012.11.013	Open record: D-lactate dehydrogenase d-LDH2, NAD+
D-lactate dehydrogenase d-LDH2	Lactobacillus jensenii	NADH	516.4	2.83	182.6	pH 8, 25 °C	doi:10.1016/j.procbio.2012.11.013	Open record: D-lactate dehydrogenase d-LDH2, NADH
D-lactate dehydrogenase D-LDH2	Sporolactobacillus inulinus	pyruvate	44.7	1.4	32	pH 7.5, 30 °C	PMID 30066438	Open record: D-lactate dehydrogenase D-LDH2, pyruvate
D-lactate dehydrogenase d-LDH3	Lactobacillus jensenii	NAD+	0.64	0.41	1.56	pH 8, 25 °C	doi:10.1016/j.procbio.2012.11.013	Open record: D-lactate dehydrogenase d-LDH3, NAD+
D-lactate dehydrogenase d-LDH3	Lactobacillus jensenii	NADH	8.28	0.04	232.6	pH 8, 25 °C	doi:10.1016/j.procbio.2012.11.013	Open record: D-lactate dehydrogenase d-LDH3, NADH
D-lactate dehydrogenase D-LDH3	Sporolactobacillus inulinus	pyruvate	10.7	3.1	3.5	pH 5.5, 30 °C	PMID 30066438	Open record: D-lactate dehydrogenase D-LDH3, pyruvate
lactate dehydrogenase	Rattus norvegicus	NADH	—	0.001	—	pH 7.2, 38 °C	PMID 7929251	Open record: lactate dehydrogenase, NADH
lactate dehydrogenase	Rattus norvegicus	pyruvate	—	0.125	—	pH 7.2, 38 °C	PMID 7929251	Open record: lactate dehydrogenase, pyruvate
NAD-dependent D-lactate dehydrogenase (D-nLDH)	Lactobacillus bulgaricus	phenylpyruvic acid	11.3	11.4	1	pH 7.5, 37 °C	PMID 24292439	Open record: NAD-dependent D-lactate dehydrogenase (D-nLDH), phenylpyruvic acid
NAD-dependent D-lactate dehydrogenase (D-nLDH)variant F299Y	Lactobacillus bulgaricus	phenylpyruvic acid	1.8	0.32	5.7	pH 7.5, 37 °C	PMID 24292439	Open record: NAD-dependent D-lactate dehydrogenase (D-nLDH) variant F299Y, phenylpyruvic acid
NAD-dependent D-lactate dehydrogenase (D-nLDH)variant Y52L	Lactobacillus bulgaricus	phenylpyruvic acid	2013	0.27	7.5 × 10³	pH 7.5, 37 °C	PMID 24292439	Open record: NAD-dependent D-lactate dehydrogenase (D-nLDH) variant Y52L, phenylpyruvic acid
NAD-dependent D-lactate dehydrogenase (D-nLDH)variant Y52L/F299Y	Lactobacillus bulgaricus	phenylpyruvic acid	1447	1.4	1 × 10³	pH 7.5, 37 °C	PMID 24292439	Open record: NAD-dependent D-lactate dehydrogenase (D-nLDH) variant Y52L/F299Y, phenylpyruvic acid
VanH	Enterococcus faecium	NADH	—	0.021	—	pH 5.6	PMID 1931965	Open record: VanH, NADH
VanH	Enterococcus faecium	NADPH	—	0.002	—	pH 5.6	PMID 1931965	Open record: VanH, NADPH
VanH	Enterococcus faecium	pyruvate	40	1.45	28	pH 5.6	PMID 1931965	Open record: VanH, pyruvate
VanH	Enterococcus faecium	α-ketobutyrate	35	2.6	14	pH 5.6	PMID 1931965	Open record: VanH, α-ketobutyrate
VanH	Enterococcus faecium	α-ketocaproate	2.4	20	0.12	pH 5.6	PMID 1931965	Open record: VanH, α-ketocaproate
VanH	Enterococcus faecium	α-ketoisocaproate	5.2	31	0.168	pH 5.6	PMID 1931965	Open record: VanH, α-ketoisocaproate
VanH	Enterococcus faecium	α-ketoisovalerate	5.2	150	0.035	pH 5.6	PMID 1931965	Open record: VanH, α-ketoisovalerate
VanH	Enterococcus faecium	α-ketovalerate	35	40	0.88	pH 5.6	PMID 1931965	Open record: VanH, α-ketovalerate