EC 6.3.2.10: UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
LigasesOpen in Browse
CatLog read 8 records for EC 6.3.2.10 from 2 papers, for 2 organisms. Names in these papers: D-Ala-D-Ala adding enzyme, MurF ligase (UDP-MurNAc-tripeptide:D-Ala-D-Ala ligase).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 1 record for EC 6.3.2.10 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 6.3.2.10 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Molecular basis for vancomycin resistance in Enterococcus faecium BM4147: biosynthesis of a depsipeptide peptidoglycan precursor by vancomycin resistance proteins VanH and VanA | Escherichia coli | 5 |
| Purification and biochemical characterization of Mur ligases from Staphylococcus aureus | Staphylococcus aureus | 3 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| D-Ala-D-Ala adding enzyme | Escherichia coli | D-alanyl-D-2-hydroxybutyrate | 9.2 | 2.6 | 3.5 | pH 8.6, 37 °C | PMID 1931965 | Open record: D-Ala-D-Ala adding enzyme, D-alanyl-D-2-hydroxybutyrate |
| D-Ala-D-Ala adding enzyme | Escherichia coli | D-alanyl-D-alanine | 18 | 0.054 | 330 | pH 8.6, 37 °C | PMID 1931965 | Open record: D-Ala-D-Ala adding enzyme, D-alanyl-D-alanine |
| D-Ala-D-Ala adding enzyme | Escherichia coli | D-alanyl-D-lactate | 13.8 | 0.095 | 150 | pH 8.6, 37 °C | PMID 1931965 | Open record: D-Ala-D-Ala adding enzyme, D-alanyl-D-lactate |
| D-Ala-D-Ala adding enzyme | Escherichia coli | D-alanyl-D-methionine | 0.57 | 21 | 0.027 | pH 8.6, 37 °C | PMID 1931965 | Open record: D-Ala-D-Ala adding enzyme, D-alanyl-D-methionine |
| D-Ala-D-Ala adding enzyme | Escherichia coli | D-alanyl-D-phenylalanine | 0.92 | 32 | 0.029 | pH 8.6, 37 °C | PMID 1931965 | Open record: D-Ala-D-Ala adding enzyme, D-alanyl-D-phenylalanine |
| MurF ligase (UDP-MurNAc-tripeptide:D-Ala-D-Ala ligase) | Staphylococcus aureus | adenosine 5'-triphosphate | — | 0.11 | — | pH 8.6, 37 °C | PMID 20659527 | Open record: MurF ligase (UDP-MurNAc-tripeptide:D-Ala-D-Ala ligase), adenosine 5'-triphosphate |
| MurF ligase (UDP-MurNAc-tripeptide:D-Ala-D-Ala ligase) | Staphylococcus aureus | D-alanyl-D-alanine | — | 0.24 | — | pH 8.6, 37 °C | PMID 20659527 | Open record: MurF ligase (UDP-MurNAc-tripeptide:D-Ala-D-Ala ligase), D-alanyl-D-alanine |
| MurF ligase (UDP-MurNAc-tripeptide:D-Ala-D-Ala ligase) | Staphylococcus aureus | UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine | — | 0.046 | — | pH 8.6, 37 °C | PMID 20659527 | Open record: MurF ligase (UDP-MurNAc-tripeptide:D-Ala-D-Ala ligase), UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine |